Effect of plasma protein adsorption on protein excretion in kidney-transplant recipients with recurrent nephrotic syndrome

1994 ◽  
Vol 8 (3) ◽  
pp. 279-279
Author(s):  
Jacques Dantal ◽  
Edith Bigot ◽  
Willy Bogers ◽  
Angelo Testa ◽  
Faiçal Kriaa ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Protein Adsorption ◽  
Kidney Transplant ◽  
Plasma Protein ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Protein Excretion ◽  
Plasma Protein Adsorption

scholarly journals First and second morning spot urine protein measurements for the assessment of proteinuria: a diagnostic accuracy study in kidney transplant recipients

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Maja Mrevlje ◽  
Manca Oblak ◽  
Gregor Mlinšek ◽  
Jelka Lindič ◽  
Jadranka-Buturović-Ponikvar ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Cross Sectional Study ◽  
Low Grade ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Urine Protein ◽  
Cross Sectional ◽  
Spot Urine ◽  
Protein Excretion ◽  
Measures Of Agreement

Abstract Background Quantification of proteinuria in kidney transplant recipients is important for diagnostic and prognostic purposes. Apart from correlation tests, there have been few evaluations of spot urine protein measurements in kidney transplantation. Methods In this cross-sectional study involving 151 transplanted patients, we investigated measures of agreement (bias and accuracy) between the estimated protein excretion rate (ePER), determined from the protein-to-creatinine ratio in the first and second morning urine, and 24-h proteinuria and studied their performance at different levels of proteinuria. Measures of agreement were reanalyzed in relation to allograft histology in 76 patients with kidney biopsies performed for cause before enrolment in the study. Results For ePER in the first morning urine, percent bias ranged from 1 to 28% and accuracy (within 30% of 24-h collection) ranged from 56 to 73%. For the second morning urine, percent bias ranged from 2 to 11%, and accuracy ranged from 71 to 78%. The accuracy of ePER (within 30%) in first and second morning urine progressively increased from 56 and 71% for low-grade proteinuria (150–299 mg/day) to 60 and 74% for moderate proteinuria (300–999 mg/day), and to 73 and 78% for high-grade proteinuria (≥1000 mg/day). Measures of agreement were similar across histologic phenotypes of allograft injury. Conclusions The ability of ePER to accurately predict 24-h proteinuria in kidney transplant recipients is modest. However, accuracy improves with an increase in proteinuria. Given the similar accuracy of ePER measurements in first and second morning urine, second morning urine can be used to monitor protein excretion.

scholarly journals Ramadan Fasting in Kidney Transplant Recipients: A Single-Centre Retrospective Study

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Ihab A. Ibrahim ◽  
Ehab A. Hassan ◽  
Abdelrahman M. Alkhan ◽  
Mohamed A. Hussein ◽  
Ahmed F. Alhabashi ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Kidney Transplant ◽  
Graft Function ◽  
Urinary Protein Excretion ◽  
Urinary Protein ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Protein Excretion ◽  
The Impact

Background. Fasting during the lunar month of Ramadan is mandatory to all healthy adult Muslims. Renal transplant recipients are often worried about the impact of fluid and electrolyte deprivation during fasting on the function of their allograft. We aimed to examine the effect of fasting Ramadan on the graft function in renal transplant recipients. Methods. This retrospective cohort study included patients who underwent kidney transplantation in our tertiary referral center. Baseline pre-Ramadan estimated glomerular filtration rate (eGFR), mean arterial pressure (MAP), and urinary protein excretion were compared to those during and after Ramadan within and between the fasting and non-fasting groups. Results. The study population included 280 kidney transplant recipients who chose to fast during the Ramadan month (June-July 2014) and 285 recipients who did not fast. In the fasting group, baseline eGFR did not change from that during or post-Ramadan (72.6±23.7 versus 72.3±24.5 mL/min/1.73 m2, P=0.53; and 72.6±23.7 versus 72±23.2 mL/min/1.73 m2, P=0.14, respectively). Compared to baseline, there were no significant differences between the fasting and the non-fasting groups in terms of mean percent changes in eGFR, MAP, and urinary protein excretion. Conclusion. Fasting during the month of Ramadan did not have significant adverse effects on renal allograft function.

scholarly journals Prevalence and Causes of Proteinuria in Kidney Transplant Recipients: Data from a Single Center

2016 ◽  
Vol 14 (1) ◽  
pp. 20-22
Author(s):  
Sibel Ersan ◽  
Senem Ertilav ◽  
Ali Celik ◽  
Aykut Sifil ◽  
Caner Cavdar ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Graft Failure ◽  
First Year ◽  
Study Group ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Protein Excretion ◽  
New Onset Diabetes Mellitus ◽  
New Onset

AbstractIntroduction. Proteinuria after renal transplantation increases the risk of graft failure and mortality. The aim of the study was to determine the prevalence and causes of proteinuria in kidney transplant recipients. Methods. All kidney transplant recipients followed up in our clinic were included in the study. As a center protocol 24-hour urine collections were used to quantify protein excretion with 3-month intervals posttransplantation during the first year, and yearly thereafter. The etiology of chronic kidney disease and demographic characteristics of the study group were obtained from outpatient records. Data regarding the immunosuppressive regimens used, 24-hour proteinuria levels and creatinine clearences, new-onset hypertension, new-onset diabetes mellitus, rejection episodes, infections like cytomegalovirus (CMV) and polyoma (BK), and biopsy findings were noted. Results. A total of 260 kidney transplant recipients (97 females, mean age 42.3±12.3 years) were evaluated. Median follow-up period was 36 months; 137 of all transplantations were from living donors. Mean age of donors was 42.7±15 years and 133 were female. Proteinuria with protein excretion ≥300 mg/d was present in 35.4% of patients. The most common cause of biopsy-proven proteinuria was transplant-specific conditions (acute rejection, and borderline changes). Conclusion. The prevalence of proteinuria was 35.4%. The transplant-specific diagnoses were the most likely causes. Even in nonnephrotic ranges it was associated with decreased graft survival.

scholarly journals First and Second Morning Spot Urine Protein Measurements for the Assessment of Proteinuria: A Diagnostic Accuracy Study in Kidney Transplant Recipients

2021 ◽  
Author(s):  
Maja Mrevlje ◽  
Manca Oblak ◽  
Gregor Mlinšek ◽  
Jadranka Buturović-Ponikvar ◽  
Jelka Lindič ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Cross Sectional Study ◽  
Low Grade ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Urine Protein ◽  
Cross Sectional ◽  
Spot Urine ◽  
Protein Excretion ◽  
Measures Of Agreement

Abstract Background. Quantification of proteinuria in kidney transplant recipients is important for diagnostic and prognostic purposes. Apart from correlation tests, there have been few evaluations of spot urine protein measurements in kidney transplantation.Methods. In this cross-sectional study involving 151 transplanted patients, we investigated measures of agreement (bias and accuracy) between the estimated protein excretion rate (ePER), determined from the protein-to-creatinine ratio in the first and second morning urine, and 24-hour proteinuria and studied their performance at different levels of proteinuria. Measures of agreement were reanalyzed in relation to allograft histology in 76 patients with kidney biopsies performed for cause before enrolment in the study.Results. For ePER in the first morning urine, percent bias ranged from 1% to 28% and accuracy (within 30% of 24-hour collection) ranged from 56% to 73%. For the second morning urine, percent bias ranged from 2% to 11%, and accuracy ranged from 71% to 78%. The accuracy of ePER (within 30%) in first and second morning urine progressively increased from 56% and 71% for low-grade proteinuria (150-299 mg/day) to 60% and 74% for moderate proteinuria (300-999 mg/day), and to 73% and 78% for high-grade proteinuria (≥1000 mg/day). Measures of agreement were similar across histologic phenotypes of allograft injury.Conclusions. The ability of ePER to accurately predict 24-hour proteinuria in kidney transplant recipients is modest. However, accuracy improves with an increase in proteinuria. Given the similar accuracy of ePER measurements in first and second morning urine, second morning urine can be used to monitor protein excretion.

1631: Evolved Techniques in Hand Assisted Laparoscopic Donor Nephrectomy Improve Outcomes in Kidney Transplant Recipients

2005 ◽  
Vol 173 (4S) ◽  
pp. 441-442
Author(s):  
Peter C. Fisher ◽  
Jeffrey S. Montgomery ◽  
Willam K. Johnston ◽  
J. Stuart Wolf
Keyword(s):  
Kidney Transplant ◽  
Donor Nephrectomy ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Laparoscopic Donor Nephrectomy

Clinical Variables and Outcomes of Kidney Transplant Recipients with Type 2 Diabetes and New-Onset Diabetes after Transplantation in a Predominantly Minority Urban Population

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 541-P
Author(s):  
SANDRA ALEKSIC ◽  
SARA ZAHEDPOUR ANARAKI ◽  
EFFIE TSOMOS ◽  
LAXMI UPADHYAY ◽  
EMILY JAPP ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Kidney Transplant ◽  
Urban Population ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Clinical Variables ◽  
Onset Diabetes ◽  
Predominantly Minority ◽  
New Onset
Sign in / Sign up

Export Citation Format

Share Document