Effects of HA1077, an intracellular calcium antagonist, on neurotransmitter metabolism in rat brainIn Vivo

1991 ◽  
Vol 6 (3) ◽  
pp. 111-124 ◽  
Author(s):  
Yasushi Kondoh ◽  
Shigenori Mizusawa ◽  
Matsutaro Murakami ◽  
Ken Nagata ◽  
Hiroyuki Nakamichi ◽  
...  
Keyword(s):  
Calcium Antagonist ◽  
Intracellular Calcium ◽  
Intracellular Calcium Antagonist ◽  
Neurotransmitter Metabolism

Hemodynamic and Electrocardiographic Actions of the New Intracellular Calcium Antagonist, KT-362, in the Conscious Dog

Pharmacology ◽  
1988 ◽  
Vol 37 (6) ◽  
pp. 376-384 ◽  
Author(s):  
Craig Hartman ◽  
Mahmood H. Al-Wathiqui ◽  
Harold L. Brooks ◽  
Garrett J. Gross ◽  
David C. Warltier
Keyword(s):  
Calcium Antagonist ◽  
Intracellular Calcium ◽  
Conscious Dog ◽  
Intracellular Calcium Antagonist

HA1004, an Intracellular Calcium Antagonist, Selectively Attenuates Pulmonary Hypertension in Newborn Lambs

1994 ◽  
Vol 23 (5) ◽  
pp. 806-813 ◽  
Author(s):  
Mark R. Crowley ◽  
Jeffrey R. Fineman ◽  
Scott J. Soifer
Keyword(s):  
Pulmonary Hypertension ◽  
Calcium Antagonist ◽  
Intracellular Calcium ◽  
Intracellular Calcium Antagonist

Evidence for mobilization of intracellular calcium during the contractile response of the rat aorta to U44069

1982 ◽  
Vol 60 (5) ◽  
pp. 743-746 ◽  
Author(s):  
Richard J. Heaslip ◽  
Ralf G. Rahwan
Keyword(s):  
Calcium Antagonist ◽  
Intracellular Calcium ◽  
Channel Blocker ◽  
Contractile Response ◽  
Rat Aorta ◽  
Extracellular Calcium ◽  
Pharmacological Mechanism ◽  
Persistent Effect ◽  
Contractile Effect ◽  
Intracellular Calcium Antagonist

The aim of the present investigation was to elucidate the pharmacological mechanism by which U44069, a stable PGH2 analogue, contracts the rat aorta. The results obtained demonstrate that while the contractile effect of potassium chloride is obliterated by removal of extracellular calcium, a substantial proportion of the contractile effect of U44069 persists under these conditions. The persistent effect of U44069 under calcium-free conditions was not diminished by nifedipine (a slow calcium channel blocker) but was blocked by 2-n-butyl-3-dimethylamino-5,6-methylenedioxyindene (an intracellular calcium antagonist). These results provide experimental evidence for the proposal that U44069 contracts the aorta in the absence of extracellular calcium by mobilizing intracellular calcium.

Effect of an intracellular calcium antagonist (TMB-8) on carbamylcholine-induced amylase release from dispersed rat pancreatic acini

Life Sciences ◽  
1984 ◽  
Vol 34 (6) ◽  
pp. 529-533 ◽  
Author(s):  
Masahiro Ikeda ◽  
Masatoshi Nagai ◽  
Seiji Suzuki ◽  
Hirohumi Niwa ◽  
Hiroshi Oka ◽  
...  
Keyword(s):  
Calcium Antagonist ◽  
Intracellular Calcium ◽  
Amylase Release ◽  
Pancreatic Acini ◽  
Intracellular Calcium Antagonist

The intracellular calcium antagonist, TMB-8, inhibits prolactin gene expression in GH3 cells

Life Sciences ◽  
1987 ◽  
Vol 41 (20) ◽  
pp. 2289-2294 ◽  
Author(s):  
Gregory M. Preston ◽  
Bruce A. White
Keyword(s):  
Gene Expression ◽  
Calcium Antagonist ◽  
Intracellular Calcium ◽  
Gh3 Cells ◽  
Prolactin Gene ◽  
Intracellular Calcium Antagonist
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