scholarly journals Variations in motor conduction velocity produced by acute changes of the metabolic state in diabetic patients

Diabetologia ◽  
1968 ◽  
Vol 4 (5) ◽  
pp. 273-277 ◽  
Author(s):  
G. Gregersen
Keyword(s):  
Conduction Velocity ◽  
Diabetic Patients ◽  
Motor Conduction Velocity ◽  
Metabolic State ◽  
Acute Changes

RETRACTED: A long-term effect of epalrestat on motor conduction velocity of diabetic patients: ARI-Diabetes Complications Trial (ADCT)

2007 ◽  
Vol 77 (3) ◽  
pp. S263-S268 ◽  
Author(s):  
Kempei Matsuoka ◽  
Nobuo Sakamoto ◽  
Yasuo Akanuma ◽  
Nigishi Hotta ◽  
Motoaki Shichiri ◽  
...  
Keyword(s):  
Conduction Velocity ◽  
Diabetes Complications ◽  
Term Effect ◽  
Diabetic Patients ◽  
Motor Conduction Velocity ◽  
Long Term Effect

scholarly journals Electroneurography of Right Median and Ulnar Nerves in Diabetic Patients With and Without Retinopathy

2007 ◽  
Vol 7 (3) ◽  
pp. 231-234
Author(s):  
Emir Tupković ◽  
Suzana Pavlješević ◽  
Mediha Nišić ◽  
Samiha Salihović
Keyword(s):  
Median Nerve ◽  
Ulnar Nerve ◽  
Conduction Velocity ◽  
Control Group ◽  
Diabetic Patients ◽  
Motor Conduction Velocity ◽  
Sensory Conduction ◽  
Conduction Velocities

In this study we examined motor and sensory conduction velocities in right median and ulnar nerves in diabetic patients. Control group consisted of 25 healthy volunteers (13 males) with average age of 52 years. The first examined group consisted of 25 diabetic patients (13 males) without retinal changes, 59,6 years old on average, and the second group consisted of 40 patients (15 males) 59,4 years old on average: 22 of them with type 1, and 18 with type 2 retinal changes. The motor and sensory conduction velocities in right median nerve in the control group were significantly higher than those measured in the first group (p<0,0005 for motor, and p=0,0027 for sensory velocity), and the second group (p<0,0001 for motor, and p=0,0001 for sensory velocity). Significantly higher conduction velocities in sensory median nerve were compared between the examined groups (p<0,001), but motor conduction velocity was not significantly higher (p=0,09). The motor conduction velocity in ulnar nerve in the control group was significantly higher in comparison with the patients of first (p=0,0027) and second examined group (p=0,0001). The sensory conduction velocity in ulnar nerve was not significantly higher compared with the first (p=0,081), and significantly higher compared with the second examined group (p<0,0001). The sensory conduction velocity of ulnar nerve was significantly higher (p=0,019) in diabetic patients without retinopathy compared with patients with retinopathy.Diabetic patients with retinal changes have higher risk of developing more severe neurophysiologic signs of neuropathy. So, simple observation with ophthalmoscope may be useful diagnostic tool in its determination and may be the target of further therapeutic strategy.

Transcarpal motor conduction velocity in carpal tunnel syndrome

2001 ◽  
Vol 24 (7) ◽  
pp. 966-968 ◽  
Author(s):  
R. Jon L. Walters ◽  
Nicholas M.F. Murray
Keyword(s):  
Carpal Tunnel Syndrome ◽  
Conduction Velocity ◽  
Carpal Tunnel ◽  
Motor Conduction Velocity ◽  
Tunnel Syndrome

The effect of liver donors’ age, gender and metabolic state on pancreatic lineage activation

2021 ◽  
Vol 16 (1) ◽  
pp. 19-31
Author(s):  
Ioan V Matei ◽  
Irit Meivar-Levy ◽  
Daniela Lixandru ◽  
Simona Dima ◽  
Ioana R Florea ◽  
...  
Keyword(s):  
Replacement Therapy ◽  
Human Liver ◽  
Liver Cells ◽  
Diabetic Patients ◽  
Metabolic State ◽  
Human Liver Cells ◽  
Metabolic States ◽  
Different Ages ◽  
Liver Donors

Autologous cells replacement therapy by liver to pancreas transdifferentiation (TD) allows diabetic patients to be also the donors of their own therapeutic tissue. Aim: To analyze whether the efficiency of the process is affected by liver donors’ heterogeneity with regard to age, gender and the metabolic state. Materials & methods: TD of liver cells derived from nondiabetic and diabetic donors at different ages was characterized at molecular and cellular levels, in vitro. Results: Neither liver cells proliferation nor the propagated cells TD efficiency directly correlate with the age (3–60 years), gender or the metabolic state of the donors. Conclusion: Human liver cells derived from a wide array of ages and metabolic states can be used for autologous cells therapies for diabetics.

scholarly journals Sensory and Motor Conduction Velocity in Spontaneously Hypertensive Rats: Sex and Aging Investigation

2019 ◽  
Vol 13 ◽  
Author(s):  
Lucas B. Fontanesi ◽  
Frederico S. Fazan ◽  
Fernando J. Dias ◽  
Maria Cristina L. Schiavoni ◽  
Wilson Marques Jr. ◽  
...  
Keyword(s):  
Conduction Velocity ◽  
Spontaneously Hypertensive Rats ◽  
Motor Conduction Velocity ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive

Prevalence of subclinical neuropathy in diabetic patients: assessment by study of conduction velocity distribution within motor and sensory nerve fibres

1998 ◽  
Vol 245 (2) ◽  
pp. 81-86 ◽  
Author(s):  
P. Bertora ◽  
Pierluigi Valla ◽  
Elisabetta Dezuanni ◽  
Maurizio Osio ◽  
Davide Mantica ◽  
...  
Keyword(s):  
Velocity Distribution ◽  
Conduction Velocity ◽  
Sensory Nerve ◽  
Diabetic Patients ◽  
Nerve Fibres ◽  
Subclinical Neuropathy ◽  
Conduction Velocity Distribution

scholarly journals Evaluation of the EndoPAT as a Tool to Assess Endothelial Function

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
M. Moerland ◽  
A. J. Kales ◽  
L. Schrier ◽  
M. G. J. van Dongen ◽  
D. Bradnock ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Endothelial Function ◽  
Healthy Volunteers ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Noninvasive Measurements ◽  
Discriminating Power ◽  
Different Populations ◽  
Acute Changes

Endothelial dysfunction is a potential target for (pharmaceutical) intervention of several systemic pathological conditions. We investigated the feasibility of the EndoPAT to evaluate acute changes in endothelial function with repeated noninvasive measurements and assessed its discriminating power in different populations. Endothelial function was stable over a longer period of time in renally impaired patients (coefficient of variation 13%). Endothelial function in renally impaired and type 2 diabetic patients was not decreased compared to healthy volunteers (2.9±1.4and1.8±0.3, resp., versus1.8±0.5,P>0.05). The EndoPAT did not detect an effect of robust interventions on endothelial function in healthy volunteers (glucose load: change from baseline0.08±0.50, 95% confidence interval −0.44 to 0.60; smoking: change from baseline0.49±0.92, 95% confidence interval −0.47 to 1.46). This suggests that at present the EndoPAT might not be suitable to assess (changes in) endothelial function in early-phase clinical pharmacology studies. Endothelial function as measured by the EndoPAT could be physiologically different from endothelial function as measured by conventional techniques. This should be investigated carefully before the EndoPAT can be considered a useful tool in drug development or clinical practice.

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