Segregation of pANCA antigenic recognition by DNase treatment of neutrophils: Ulcerative colitis, type 1 autoimmune hepatitis, and primary sclerosing cholangitis

1995 ◽  
Vol 15 (6) ◽  
pp. 293-299 ◽  
Author(s):  
Alda Vidrich ◽  
Jonathan Lee ◽  
Ellin James ◽  
Linda Cobb ◽  
Stephan Targan
2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Hon Yan Ng ◽  
Orlee R. Guttman ◽  
Lori B. Tucker

Abstract Background Chronic Recurrent Multifocal Osteomyelitis (CRMO) is a condition characterized by sterile bone inflammation, usually occurring in childhood. Although the etiology remains unclear, this condition has been associated with inflammatory bowel disease (IBD). Primary sclerosing cholangitis (PSC) and Autoimmune Hepatitis (AIH) are also uncommon pediatric conditions with a known association with IBD. Case presentation We present a unique case of a pediatric patient with an initial diagnosis of CRMO, with subsequent diagnosis of autoimmune hepatitis and PSC overlap, and eventually IBD. Conclusions Patients with CRMO may also develop PSC in addition to IBD, further highlighting the importance of IBD pathophysiology in both conditions. Clinical screening of associated gastrointestinal findings may be of value in patients with CRMO.


2019 ◽  
Vol 0 (1) ◽  
pp. 92-94
Author(s):  
О. П. Федорова ◽  
Н. Г. Горбаткова ◽  
О. В. Дудко ◽  
С. І. Свистун

2021 ◽  
Vol 1 (6) ◽  
pp. 26-30
Author(s):  
T. S. Krolevets ◽  
M. A. Livzan ◽  
M. I. Plinder

The article presents a clinical case of cross-syndrome of autoimmune hepatitis type 1 with primary sclerosing cholangitis. The main symptoms, laboratory and instrumental criteria of these diseases are discussed. Detection of specific antibodies is necessary for an accurate diagnosis. Interpretation of changes in the colon obtained by stepwise biopsy requires special attention. The described morphological picture does not allow to make an accurate diagnosis, it can be regarded as initial manifestations of Crohn's disease, microscopic or eosinophilic colitis, signs of worm-parasitic invasion. An example of a differential diagnostic search in such a situation is discussed.


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