Treatment of complicated urinary tract infections with sisomicin a comparison of once daily and twice daily dosage forms

Infection ◽  
1976 ◽  
Vol 4 (S4) ◽  
pp. S498-S500 ◽  
Author(s):  
P. Madsen ◽  
T. Kjaer ◽  
A. Mosegaard
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Dosage Forms ◽  
Once Daily ◽  
Tract Infections

scholarly journals Once-Daily Plazomicin for Complicated Urinary Tract Infections

2019 ◽  
Vol 380 (8) ◽  
pp. 729-740 ◽  
Author(s):  
Florian M.E. Wagenlehner ◽  
Daniel J. Cloutier ◽  
Allison S. Komirenko ◽  
Deborah S. Cebrik ◽  
Kevin M. Krause ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Once Daily ◽  
Tract Infections

scholarly journals Use of Intravesicular Amikacin Irrigations for the Treatment and Prophylaxis of Urinary Tract Infections in a Patient with Spina Bifida and Neurogenic Bladder: A Case Report

2011 ◽  
Vol 16 (2) ◽  
pp. 102-107
Author(s):  
Donna Huynh ◽  
Jill A. Morgan
Keyword(s):  
Case Report ◽  
Urinary Tract ◽  
Spina Bifida ◽  
Neurogenic Bladder ◽  
Urinary Tract Infections ◽  
Multidrug Resistant ◽  
Multiple Drug ◽  
Once Daily ◽  
Multiple Drug Resistant ◽  
Tract Infections

ABSTRACT This case report describes the use of intravesicular amikacin irrigations to treat and prevent urinary tract infections (UTIs) in a pediatric patient with spina bifida and neurogenic bladder. A 15 year old Hispanic female was admitted for a UTI caused by Enterobacter cloacae and multiple-drug resistant Pseudomonas aeruginosa. A 7 day course of daily intravenous amikacin and ceftazidime was initiated along with twice daily intravesicular amikacin irrigations (15 mg/30 mL) with a dwell time of 2 hours. The patient improved and was discharged on prophylactic Bactrim SS (sulfamethoxazole/trimethoprim) 1 tablet daily and intravesicular amikacin irrigations (15 mg/30 mL) once every other day. Approximately 2 months after discharge, the patient developed another UTI from multidrug resistant Escherichia coli and was treated with a 14 day course of daily intravenous ciprofloxacin accompanied by daily intravesicular amikacin irrigations. Adjunctive therapy with either once daily or twice daily intravesicular amikacin irrigations successfully treated the patient's UTI. However, prophylactic treatment with intravesicular amikacin failed to prevent future UTIs in this patient.

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