Estimation of cardiac index by means of the arterial and the mixed venous oxygen content and pulmonary oxygen uptake determination in the early post-operative period following surgery of congenital heart disease

1994 ◽  
Vol 20 (7) ◽  
pp. 500-503 ◽  
Author(s):  
G. Buheitel ◽  
J. Scharf ◽  
M. Hofbeck ◽  
H. Singer

2009 ◽  
Vol 133 (1) ◽  
pp. 74-79 ◽  
Author(s):  
Alessandro Giardini ◽  
Salvatore Specchia ◽  
Gaetano Gargiulo ◽  
Diego Sangiorgi ◽  
Fernando M. Picchio


2020 ◽  
Vol 12 (1) ◽  
pp. 153 ◽  
Author(s):  
A. Gavotto ◽  
D. Vandenberghe ◽  
H. Abassi ◽  
H. Bertet ◽  
V. Macioce ◽  
...  


Blood ◽  
1987 ◽  
Vol 70 (3) ◽  
pp. 822-826 ◽  
Author(s):  
P Haga ◽  
PM Cotes ◽  
JA Till ◽  
BD Minty ◽  
EA Shinebourne

Abstract Serum immunoreactive erythropoietin (siEp) was measured in 27 cyanotic and 21 acyanotic children with congenital heart disease, age 4 months to 10 years. The geometric mean value was 9 mIU/mL for each group with 95% range from 3 to 26 mIU/mL and 4 to 22 mIU/mL for the cyanotic and acyanotic subjects, respectively. The levels are similar to those found in normal adults using the same assay system. Three cyanotic subjects showed increased siEp values. One was anemic relative to his hypoxemia, and the other two showed signs of increasing hypoxia. There was a significant negative correlation between siEp and arterial oxygen content. However, siEp did not correlate significantly with hemoglobin, hematocrit, PaO2, or SaO2. Despite normal siEp levels, the cyanotic children showed compensatory erythropoiesis with significantly elevated hemoglobin and hematocrit levels, which did correlate inversely with PaO2 and SaO2. Arterial oxygen content was also significantly higher in the cyanotic subjects (p less than 0.02). The cyanotic children seemed to display the same pattern as observed in man and animals exposed to prolonged hypobaric hypoxia, where after an initial rise in erythropoietin values the levels fall to normal, while increased erythropoiesis is sustained.



2020 ◽  
pp. 1-7
Author(s):  
Julius M. Woile ◽  
Stefan Dirks ◽  
Friederike Danne ◽  
Felix Berger ◽  
Stanislav Ovroutski

Abstract Aim: Regular evaluation of physical capacity takes a crucial part in long-term follow-up in patients with congenital heart disease (CHD). This study aims to examine the accuracy of self-estimated exercise capacity compared to objective assessments by cardiopulmonary exercise testing in patients with CHD of various complexity. Methods: We conducted a single centre, cross-sectional study with retrospective analysis on 382 patients aged 8–68 years with various CHD who completed cardiopulmonary exercise tests. Peak oxygen uptake was measured. Additionally, questionnaires covering self-estimation of exercise capacity were completed. Peak oxygen uptake was compared to patient’s self-estimated exercise capacity with focus on differences between complex and non-complex defects. Results: Peak oxygen uptake was 25.5 ± 7.9 ml/minute/kg, corresponding to 75.1 ± 18.8% of age- and sex-specific reference values. Higher values of peak oxygen uptake were seen in patients with higher subjective rating of exercise capacity. However, oxygen uptake in patients rating their exercise capacity as good (mean oxygen uptake 78.5 ± 1.6%) or very good (mean oxygen uptake 84.8 ± 4.8%) was on average still reduced compared to normal. In patients with non-complex cardiac defects, we saw a significant correlation between peak oxygen uptake and self-estimated exercise capacity (spearman-rho −0.30, p < 0.001), whereas in patients with complex cardiac defects, no correlation was found (spearman-rho −0.11, p < 0.255). Conclusion: The mismatch between self-estimated and objectively assessed exercise capacity is most prominent in patients with complex CHD. Registration number at Charité Universitätsmedizin Berlin Ethics Committee: EA2/106/14.



PEDIATRICS ◽  
1950 ◽  
Vol 6 (1) ◽  
pp. 93-97
Author(s):  
HERBERT N. HULTGREN ◽  
ADELINE J. HACKETT

A previously described technic of collecting and analyzing capillary blood for oxygen content has been modified slightly and applied in the study of children with congenital heart disease. Samples obtained and analyzed in this manner differed in oxygen content from simultaneously drawn arterial samples by no more than 0.4 volumes per cent. The value of the technic in the study of congenital heart disease has been illustrated.



2000 ◽  
Vol 21 (4) ◽  
pp. 378-381 ◽  
Author(s):  
J. Takaya ◽  
Y. Ikemoto ◽  
M. Teraguchi ◽  
S. Nogi ◽  
Y. Kobayashi


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