Ambulatory blood pressure in patients with Parkinson's disease without and with orthostatic hypotension

1992 ◽  
Vol 2 (2) ◽  
pp. 99-104 ◽  
Author(s):  
Jean-Michel Senard ◽  
Bernard Chamontin ◽  
André Rascol ◽  
Jean-Louis Montastruc
1992 ◽  
Vol 2 (5) ◽  
pp. 354-354
Author(s):  
Jean-Michel Senard ◽  
Bernard Chamontin ◽  
André Rascol ◽  
Jean-Louis Montastruc

2019 ◽  
Vol 42 (10) ◽  
pp. 1552-1560 ◽  
Author(s):  
Fabrizio Vallelonga ◽  
Alberto Romagnolo ◽  
Aristide Merola ◽  
Gabriele Sobrero ◽  
Cristina Di Stefano ◽  
...  

2021 ◽  
Vol 11 (2) ◽  
pp. 129
Author(s):  
Delia Tulbă ◽  
Liviu Cozma ◽  
Paul Bălănescu ◽  
Adrian Buzea ◽  
Cristian Băicuș ◽  
...  

(1) Background: Cardiovascular autonomic dysfunction is a non-motor feature in Parkinson’s disease with negative impact on functionality and life expectancy, prompting early detection and proper management. We aimed to describe the blood pressure patterns reported in patients with Parkinson’s disease, as measured by 24-h ambulatory blood pressure monitoring. (2) Methods: We conducted a systematic search on the PubMed database. Studies enrolling patients with Parkinson’s disease undergoing 24-h ambulatory blood pressure monitoring were included. Data regarding study population, Parkinson’s disease course, vasoactive drugs, blood pressure profiles, and measurements were recorded. (3) Results: The search identified 172 studies. Forty studies eventually fulfilled the inclusion criteria, with 3090 patients enrolled. Abnormal blood pressure profiles were commonly encountered: high blood pressure in 38.13% of patients (938/2460), orthostatic hypotension in 38.68% (941/2433), supine hypertension in 27.76% (445/1603) and nocturnal hypertension in 38.91% (737/1894). Dipping status was also altered often, 40.46% of patients (477/1179) being reverse dippers and 35.67% (310/869) reduced dippers. All these patterns were correlated with negative clinical and imaging outcomes. (4) Conclusion: Patients with Parkinson’s disease have significantly altered blood pressure patterns that carry a negative prognosis. Ambulatory blood pressure monitoring should be validated as a biomarker of PD-associated cardiovascular dysautonomia and a tool for assisting therapeutic interventions.


2021 ◽  
Author(s):  
Liwei Shen ◽  
Xiaoli Yang ◽  
Wenmei Lu ◽  
Weijie Chen ◽  
Xiaofei Ye ◽  
...  

2016 ◽  
Vol 4 (3) ◽  
pp. 329-334 ◽  
Author(s):  
Daan C. Velseboer ◽  
Rob J. de Haan ◽  
Bart Post ◽  
C.T.P. Paul Krediet ◽  
Hein J. Verberne ◽  
...  

2021 ◽  
Vol 15 (11) ◽  
pp. 2886-2889
Author(s):  
Ali Qayyum ◽  
Ehsan Ul Haq ◽  
Shoaib Zafar ◽  
Javaria . ◽  
Muhammad Moss ◽  
...  

Background: Parkinson’s Diseases (PD) cause some non-motor issues that could lead to disability. One of such determinal non-motor symptoms is orthostatic hypotension (OH) which is still understudied in our local setting despite of its high prevalence worldwide among patients of PD. Aim: To determine frequency of orthostatic hypotension in Parkinson’s disease Methods: This Cross-sectional study was conducted at Department of Neurology, Mayo Hospital, Lahore for 6 months after the approval of synopsis [April 9, 2018 till Oct 9, 2018]. A sample of 95 cases was selected using non probability consecutive sampling from 95 patients of Parkinson’s Disease aged 25 years and more. After taking consent from patient and recording sociodemographic information, a lying-to-standing orthostatic test was performed to evaluate the orthostatic hypotension and SBP and DBP was recorded. All data was collected using a self structured proforma and analyzed using SPSS v 21. Results: The mean age of cases was 47.46 ± 8.97 years with male to female ratio of 1.97:1. The mean systolic and diastolic blood pressure was 120.60 ± 11.80 and 86.20 ± 8.68 respectively. The frequency of orthostatic hypotension was seen in 51(53.7%) while other 44(46.3%) cases did not have orthostatic hypotension. Conclusion: Through the findings of this study we conclude that frequency of orthostatic hypotension in Parkinson’s disease is very much high i.e. 53.7% with highest frequency in cases with longer duration of disease. Keywords: Autonomic diseases, Parkinson’s disease, Systolic blood pressure, diastolic blood pressure, Orthostatic hypotension,


2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Sita Sommer ◽  
Billur Aral-Becher ◽  
Wolfgang Jost

Objective. The aim of this study was to identify patients with Parkinson's disease who showed loss or decrease of nocturnal blood pressure fall (nondipper patients) as a marker of autonomic dysfunction. Presence or absence of orthostatic hypotension was considered to investigate whether alterations in circadian blood pressure pattern are associated with posture-related dysregulation of blood pressure.Methods. 40 patients with Parkinson's disease underwent 24-hour blood pressure monitoring. 21 patients were diagnosed with arterial hypertension and received anti-hypertensive drugs. Nondipper patients were defined as having nocturnal decrease of mean systolic and diastolic blood pressure less than 10%. Presence or absence of orthostatic hypotension was determined by Schellong's test.Results. We identified 35 nondipper patients (88%). Nondipping was detected in 20 patients with orthostatic hypotension (95%) and in 15 patients without orthostatic hypotension (79%). 18 patients with hypertensive and 22 patients with normal blood pressure values were detected.Conclusions. In conclusion 24-hour blood pressure monitoring showed a high prevalence of nondipping in 40 patients with Parkinson's disease with and without orthostatic hypotension independent of coexisting arterial hypertension and antihypertensive treatment. 24-hour blood pressure monitoring may be useful to identify non-dipping as a marker of autonomic dysfunction in patients with Parkinson's disease.


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