Differences in serum tumor markers between colon and rectal cancer

1996 ◽  
Vol 39 (7) ◽  
pp. 799-805 ◽  
Author(s):  
Monika A. Carpelan-Holmström ◽  
Caj H. Haglund ◽  
Peter J. Roberts
Keyword(s):  
Rectal Cancer ◽  
Tumor Markers ◽  
Serum Tumor Markers ◽  
Colon And Rectal Cancer

Serum Tumor Markers in Stage I-II Breast Cancer

2016 ◽  
Vol 12 (3) ◽  
pp. 285-289 ◽  
Author(s):  
Renato Tozzoli ◽  
Federica D';Aurizio ◽  
Flavio Falcomer ◽  
Stefano M.M. Basso ◽  
Franco Lumachi
Keyword(s):  
Breast Cancer ◽  
Tumor Markers ◽  
Stage I ◽  
Serum Tumor Markers

scholarly journals Evaluation of potential tumor markers that may predict neoadjuvant treatment efficiency in rectal cancer

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Fatma Demet Arslan ◽  
Ayse Kocak ◽  
Cengiz Aydın ◽  
Emel Ebru Pala ◽  
Dilek Oncel ◽  
...  
Keyword(s):  
Gene Expression ◽  
Rectal Cancer ◽  
Tumor Markers ◽  
Locally Advanced ◽  
Neoadjuvant Treatment ◽  
Beclin 1 ◽  
Tumor Regression Grade ◽  
Protein Levels ◽  
Study Gene Expression ◽  
Regression Grade

AbstractObjectivesThe recurrence of rectal cancer or its resistance to neoadjuvant treatment develops due to the adaptation to hypoxia, apoptosis or autophagy. Survivin, one of the inhibitors of apoptosis; Beclin 1, which is a positive regulator in the autophagy pathway; and hypoxia-inducible factor-1α (HIF-1α) and carbonic anhydrase-9 (CA9), which are associated with tumor tissue hypoxia, may be related to resistance to treatment. Our aim was to evaluate the potential tumor markers that may help to monitor the response to neoadjuvant treatment in locally advanced rectal cancer (RC).MethodsTwenty-five patients with locally advanced RC were included in the study. Gene expression and protein levels of Beclin 1, Survivin, HIF-1α, and CA9 were analyzed in fresh tissue specimens and blood samples. The relationships of these markers to tumor staging and regression grade were evaluated.ResultsHigher blood CA9 gene expression levels and lower blood HIF-1α protein levels were found in the response group according to tumor regression grade. After neoadjuvant treatment, tissue Beclin 1 and blood Survivin gene expressions and tissue CA9, blood Beclin 1 and blood HIF-1α protein levels decreased significantly.ConclusionBeclin 1, Survivin, HIF-1α ve CA9 may help to predict the effects of the applied treatment approach.

Safety and efficacy of endoscopic colonic stenting as a bridge to surgery in the management of intestinal obstruction due to left colon and rectal cancer: A systematic review and meta-analysis

2013 ◽  
Vol 22 (1) ◽  
pp. 14-21 ◽  
Author(s):  
Roberto Cirocchi ◽  
Eriberto Farinella ◽  
Stefano Trastulli ◽  
Jacopo Desiderio ◽  
Chiara Listorti ◽  
...  
Keyword(s):  
Systematic Review ◽  
Rectal Cancer ◽  
Intestinal Obstruction ◽  
Meta Analysis ◽  
Left Colon ◽  
Bridge To Surgery ◽  
Safety And Efficacy ◽  
Colonic Stenting ◽  
Colon And Rectal Cancer

scholarly journals Characteristics of TP53 and CTNNB1 Mutation According to the Serum Tumor Markers in Hepatocellular Carcinoma

HPB ◽  
2021 ◽  
Vol 23 ◽  
pp. S141-S142
Author(s):  
K.S. Ahn ◽  
K.J. Kang ◽  
Y.H. Kim ◽  
T.-S. Kim ◽  
S.J. Park ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Tumor Markers ◽  
Serum Tumor Markers ◽  
Ctnnb1 Mutation

scholarly journals German oncology certification system for colorectal cancer – relative survival rates of a single certified centre vs. national and international registry data

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Maximilian Richter ◽  
Lena Sonnow ◽  
Amir Mehdizadeh-Shrifi ◽  
Axel Richter ◽  
Rainer Koch ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Rectal Cancer ◽  
International Comparison ◽  
Cancer Registry ◽  
Survival Data ◽  
Survival Rates ◽  
Relative Survival ◽  
Registry Data ◽  
Cancer Registry Data ◽  
Colon And Rectal Cancer

Abstract Objectives To evaluate how the certification of specialised Oncology Centres in Germany affects the relative survival of patients with colorectal cancer (CRC) by means of national and international comparison. Methods Between 2007 and 2013, 675 patients with colorectal cancer, treated at the Hildesheim Hospital, an academic teaching hospital of the Hannover Medical School (MHH), were included. A follow-up of the entire patient group was performed until 2014. To obtain international data, a SEER-database search was done. The relative survival of 148,957 patients was compared to our data after 12, 36 and 60 months. For national survival data, we compared our rates with 41,988 patients of the Munich Cancer Registry (MCR). Results Relative survival at our institution tends to be higher in advanced tumour stages compared to national and international cancer registry data. Nationally we found only little variation in survival rates for low stages CRC (UICC I and II), colon, and rectal cancer. There were notable variations regarding relative survival rates for advanced CRC tumour stages (UICC IV). These variations were even more distinct for rectal cancer after 12, 36 and 60 months (Hildesheim Hospital: 89.9, 40.3, 30.1%; Munich Cancer Registry (MCR): 65.4, 28.7, 16.6%). The international comparison of CRC showed significantly higher relative survival rates for patients with advanced tumour stages after 12 months at our institution (77 vs. 54.9% for UICC IV; raw p<0.001). Conclusions Our findings suggest that patients with advanced tumour stages of CRC and especially rectal cancer benefit most from a multidisciplinary and guidelines-oriented treatment at Certified Oncology Centres. For a better evaluation of cancer treatment and improved national and international comparison, the creation of a centralised national cancer registry is necessary.

scholarly journals Factors in prognosis of colon and rectal cancer

Cancer ◽  
1971 ◽  
Vol 28 (1) ◽  
pp. 213-218 ◽  
Author(s):  
Oliver H. Beahrs ◽  
Peter M. Sanfelippo
Keyword(s):  
Rectal Cancer ◽  
Colon And Rectal Cancer

Practice Guideline for the Surveillance of Patients After Curative Treatment of Colon and Rectal Cancer

2015 ◽  
Vol 58 (8) ◽  
pp. 713-725 ◽  
Author(s):  
Scott R. Steele ◽  
George J. Chang ◽  
Samantha Hendren ◽  
Marty Weiser ◽  
Jennifer Irani ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Practice Guideline ◽  
Curative Treatment ◽  
Colon And Rectal Cancer

Treatment of Colon and Rectal Cancer

2002 ◽  
Vol 34 (1) ◽  
pp. 15-26 ◽  
Author(s):  
David Blumberg ◽  
Ramesh K. Ramanathan
Keyword(s):  
Rectal Cancer ◽  
Colon And Rectal Cancer

Thoracotomy for colon and rectal cancer metastases

1993 ◽  
Vol 36 (5) ◽  
pp. 425-429 ◽  
Author(s):  
Theodore J. Saclarides ◽  
Barbara L. Krueger ◽  
Debra J. Szeluga ◽  
William H. Warren ◽  
Penfield L. Faber ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Cancer Metastases ◽  
Colon And Rectal Cancer
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