Differential effect of antipsychotics on place navigation of rats in the Morris water maze

1996 ◽  
Vol 124 (1-2) ◽  
pp. 126-133 ◽  
Author(s):  
T. Skarsfeldt
Keyword(s):  
Morris Water Maze ◽  
Differential Effect ◽  
Water Maze ◽  
Place Navigation

Variants of the Morris water maze task to comparatively assess human and rodent place navigation

2017 ◽  
Vol 139 ◽  
pp. 117-127 ◽  
Author(s):  
Robby Schoenfeld ◽  
Thomas Schiffelholz ◽  
Christian Beyer ◽  
Bernd Leplow ◽  
Nigel Foreman
Keyword(s):  
Morris Water Maze ◽  
Water Maze ◽  
Maze Task ◽  
Water Maze Task ◽  
Place Navigation ◽  
Morris Water Maze Task

Place navigation in the morris water maze under minimum and redundant extra-maze cue conditions

1994 ◽  
Vol 62 (3) ◽  
pp. 178-189 ◽  
Author(s):  
Andre A. Fenton ◽  
Maria Pia Arolfo ◽  
Jan Bures
Keyword(s):  
Morris Water Maze ◽  
Water Maze ◽  
Place Navigation

Scopolamine disrupts place navigation in rats and humans: a translational validation of the Hidden Goal Task in the Morris water maze and a real maze for humans

2016 ◽  
Vol 234 (4) ◽  
pp. 535-547 ◽  
Author(s):  
Jan Laczó ◽  
Hana Markova ◽  
Veronika Lobellova ◽  
Ivana Gazova ◽  
Martina Parizkova ◽  
...  
Keyword(s):  
Morris Water Maze ◽  
Water Maze ◽  
Place Navigation

scholarly journals Cognitive functions and drug sensitivity in adult male rats prenatally exposed to methamphetamine

2009 ◽  
pp. 741-750
Author(s):  
B Schutová ◽  
L Hrubá ◽  
M Pometlová ◽  
K Deykun ◽  
R Šlamberová
Keyword(s):  
Morris Water Maze ◽  
Adult Male ◽  
Cognitive Functions ◽  
Water Maze ◽  
Memory Test ◽  
Male Rats ◽  
Prenatally Exposed ◽  
Place Navigation ◽  
Probe Test ◽  
Navigation Test

The aim of the present study was to investigate the impact of prenatal methamphetamine (MA) exposure and application of the same drug in adulthood on cognitive functions of adult male rats tested in Morris water maze (MWM). Adult male rats prenatally exposed to MA (5 mg/kg), saline or no injection were examined. Half of the animals were injected daily with MA (1 mg/kg) after finishing the testing. Three types of tests were used: (1) “Place navigation test” (Learning), (2) “Probe test” and (3) “Retention memory test” (Memory). Our results showed that prenatal MA exposure did not affect the test of learning and the Probe test. In the test of memory prenatally MA-exposed rats showed smaller search errors and used spatial strategies more than both control groups. Further, MA application in adulthood prolonged trajectories, increased the incidence of random search and decreased the incidence of direct swim in the Place navigation test. In addition, MA administration in adulthood increased the speed of swimming regardless of prenatal exposure. The present study thus demonstrates that 1) Prenatal MA exposure does not affect learning in the MWM, 2) Prenatal MA exposure improves performance in the Retention memory test in the MWM, and 3) MA application in adulthood impairs learning in the Morris water maze.

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