Object manipulation by wild red colobus monkeys living in the Abuko Nature Reserve, the Gambia

Primates ◽  
1990 ◽  
Vol 31 (3) ◽  
pp. 385-391 ◽  
Author(s):  
E. D. Starin
Keyword(s):  
Nature Reserve ◽  
Object Manipulation ◽  
The Gambia ◽  
Red Colobus ◽  
Red Colobus Monkeys ◽  
Colobus Monkeys

scholarly journals Threats to the monkeys of The Gambia

Oryx ◽  
1989 ◽  
Vol 23 (4) ◽  
pp. 208-214 ◽  
Author(s):  
E. D. Starin
Keyword(s):  
Nature Reserve ◽  
Habitat Destruction ◽  
The Gambia ◽  
Red Colobus ◽  
Term Study ◽  
Long Term Study ◽  
Conservation Plan ◽  
Forest Parks ◽  
Colobus Monkey

There are five, perhaps only four, monkey species in The Gambia and all are under threat. The main problems are habitat destruction, hunting of crop raiders and illegal capture for medical research. The information presented here was collected during a long-term study from March 1978 to September 1983 on the socio-ecology of the red colobus monkey in the Abuko Nature Reserve. Further information was collected during brief periods between February 1985 and April 1989 on the presence of monkeys in the forest parks. It is not systematic nor extensive, but it indicates clearly that action is needed if monkeys are to remain as part of the country's wildlife. The most pressing need is for survey work to supply the information needed to work out a conservation plan.

scholarly journals Immunogenetic response to a malaria-like parasite in a wild primate

2020 ◽  
Author(s):  
Amber E. Trujillo ◽  
Christina M. Bergey
Keyword(s):  
Genetic Architecture ◽  
Arms Race ◽  
Cell Type ◽  
Red Colobus ◽  
Malaria Parasites ◽  
Human Malaria ◽  
Red Colobus Monkeys ◽  
Colobus Monkeys ◽  
Genetic Mechanisms ◽  
Human Primate

AbstractMalaria is infamous for the massive toll it exacts on human life and health. In the face of this intense selection, many human populations have evolved mechanisms that confer some resistance to the disease, such as sickle-cell hemoglobin or the Duffy null blood group. Less understood are adaptations in other vertebrate hosts, many of which have a longer history of co-evolution with malaria parasites. By comparing malaria resistance adaptations across host species, we can gain fundamental insight into host-parasite co-evolution. In particular, understanding the mechanisms by which non-human primate immune systems combat malaria may be fruitful in uncovering transferable therapeutic targets for humans. However, most research on primate response to malaria has focused on a single or few loci, typically in experimentally-infected captive primates. Here, we report the first transcriptomic study of a wild primate response to a malaria-like parasite, investigating gene expression response of red colobus monkeys (Piliocolobus tephrosceles) to natural infection with the malaria-like parasite, Hepatocystis. We identified colobus genes with expression strongly correlated with parasitemia, including many implicated in human malaria and suggestive of common genetic architecture of disease response. For instance, the expression of ACKR1 (alias DARC) gene, previously linked to resistance in humans, was found to be positively correlated with parasitemia. Other similarities to human parasite response include induction of changes in immune cell type composition and, potentially, increased extramedullary hematopoiesis and altered biosynthesis of neutral lipids. Our results illustrate the utility of comparative immunogenetic investigation of malaria response in primates. Such inter-specific comparisons of transcriptional response to pathogens afford a unique opportunity to compare and contrast the adaptive genetic architecture of disease resistance, which may lead to the identification of novel intervention targets to improve human health.Author SummaryThe co-evolutionary arms race between humans and malaria parasites has been ongoing for millennia. Fully understanding the evolved human response to malaria is impossible without comparative study of parasites in our non-human primate relatives. Though laboratory primates are fruitful models, the complexity of wild primates infected in a natural transmission system may be a more suitable comparison for contextualizing malaria infections in human patients. Here, we investigate the genetic mechanisms underlying the immune response to Hepatocystis, a close relative of human-infective malaria, in a population of wild Ugandan red colobus monkeys. We find that the genes involved have considerable overlap with those active in human malaria patients. Like Plasmodium, Hepatocystis induces changes in blood cell type and may cause the host to produce blood components outside of the bone marrow or alter metabolism related to the production of lipids. Our work helps to identify the genetic mechanisms underlying the arms race between primates and malaria parasites, providing fundamental evolutionary insight. Such comparative work on the interaction between wild non-human primates and malaria parasites can identify ways in which primates have evolved resistance to malaria parasites, and further investigation of such implicated genes may lead to novel potential therapeutic and vaccine targets.

Bigger groups have fewer parasites and similar cortisol levels: a multi-group analysis in red colobus monkeys

2008 ◽  
Vol 70 (11) ◽  
pp. 1072-1080 ◽  
Author(s):  
Tamaini V. Snaith ◽  
Colin A. Chapman ◽  
Jessica M. Rothman ◽  
Michael D. Wasserman
Keyword(s):  
Group Analysis ◽  
Red Colobus ◽  
Red Colobus Monkeys ◽  
Colobus Monkeys ◽  
Cortisol Levels
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