Evaluation of renal allograft function by Doppler spectrum analysis

1989 ◽  
Vol 2 (1) ◽  
pp. 16-22 ◽  
Author(s):  
S. H. Skotnicki ◽  
W. N. J. C. Asten ◽  
W. J. Beijneveld ◽  
R. Roosmalen ◽  
A. J. Hoitsma ◽  
...  
Keyword(s):  
Spectrum Analysis ◽  
Renal Allograft ◽  
Doppler Spectrum ◽  
Allograft Function

Evaluation of renal allograft function by Doppler spectrum analysis A preliminary study

1989 ◽  
Vol 2 (1) ◽  
pp. 16-22
Author(s):  
S. H. Skotnicki ◽  
W. N. J. C. Asten ◽  
W. J. Beijneveld ◽  
R. Roosmalen ◽  
A. J. Hoitsma ◽  
...  
Keyword(s):  
Spectrum Analysis ◽  
Renal Allograft ◽  
Doppler Spectrum ◽  
Allograft Function ◽  
Preliminary Study

Iliac Artery Histology and Renal Allograft Blood Flow Measured by Doppler Spectrum Analysis

1997 ◽  
pp. 234-234
Author(s):  
J. Pascual ◽  
T. Cano ◽  
F. J. Burgos ◽  
C. Cuesta ◽  
A. Tato ◽  
...  
Keyword(s):  
Blood Flow ◽  
Iliac Artery ◽  
Spectrum Analysis ◽  
Renal Allograft ◽  
Doppler Spectrum

Haemodynamic changes in human kidney allografts following administration of nifedipine: assessment with doppler spectrum analysis

1992 ◽  
Vol 5 ◽  
pp. S17-S20 ◽  
Author(s):  
J. W. S. Merkus ◽  
L. B. Hilbrands ◽  
A. J. Hoitsma ◽  
W. N. J. C. van Asten ◽  
R. A. P. Koene ◽  
...  
Keyword(s):  
Spectrum Analysis ◽  
Human Kidney ◽  
Doppler Spectrum ◽  
Haemodynamic Changes

scholarly journals Preservation of epoxyeicosatrienoic acid bioavailability prevents renal allograft dysfunction and cardiovascular alterations in kidney transplant recipients

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Thomas Duflot ◽  
Charlotte Laurent ◽  
Anne Soudey ◽  
Xavier Fonrose ◽  
Mouad Hamzaoui ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Kidney Transplant ◽  
Plasma Levels ◽  
Renal Allograft ◽  
Transplant Recipients ◽  
Loss Of Function ◽  
Kidney Transplant Recipients ◽  
Allograft Dysfunction ◽  
Allograft Function ◽  
The Impact

AbstractThis study addressed the hypothesis that epoxyeicosatrienoic acids (EETs) synthesized by CYP450 and catabolized by soluble epoxide hydrolase (sEH) are involved in the maintenance of renal allograft function, either directly or through modulation of cardiovascular function. The impact of single nucleotide polymorphisms (SNPs) in the sEH gene EPHX2 and CYP450 on renal and vascular function, plasma levels of EETs and peripheral blood monuclear cell sEH activity was assessed in 79 kidney transplant recipients explored at least one year after transplantation. Additional experiments in a mouse model mimicking the ischemia–reperfusion (I/R) injury suffered by the transplanted kidney evaluated the cardiovascular and renal effects of the sEH inhibitor t-AUCB administered in drinking water (10 mg/l) during 28 days after surgery. There was a long-term protective effect of the sEH SNP rs6558004, which increased EET plasma levels, on renal allograft function and a deleterious effect of K55R, which increased sEH activity. Surprisingly, the loss-of-function CYP2C9*3 was associated with a better renal function without affecting EET levels. R287Q SNP, which decreased sEH activity, was protective against vascular dysfunction while CYP2C8*3 and 2C9*2 loss-of-function SNP, altered endothelial function by reducing flow-induced EET release. In I/R mice, sEH inhibition reduced kidney lesions, prevented cardiac fibrosis and dysfunction as well as preserved endothelial function. The preservation of EET bioavailability may prevent allograft dysfunction and improve cardiovascular disease in kidney transplant recipients. Inhibition of sEH appears thus as a novel therapeutic option but its impact on other epoxyfatty acids should be carefully evaluated.

A direct association of polyomavirus BK viruria with deterioration of renal allograft function in renal transplant patients

2009 ◽  
Vol 23 (4) ◽  
pp. 505-510 ◽  
Author(s):  
Yi-Jung Li ◽  
Yung-Chang Chen ◽  
Ping-Chin Lai ◽  
Ji-Tseng Fang ◽  
Chih-Wei Yang ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Renal Allograft ◽  
Transplant Patients ◽  
Direct Association ◽  
Allograft Function ◽  
Polyomavirus Bk ◽  
Renal Transplant Patients

Prediction of renal allograft function with early Doppler ultrasonography

2004 ◽  
Vol 36 (5) ◽  
pp. 1348-1351 ◽  
Author(s):  
S Kahraman ◽  
G Genctoy ◽  
B Cil ◽  
R Yilmaz ◽  
M Arici ◽  
...  
Keyword(s):  
Doppler Ultrasonography ◽  
Renal Allograft ◽  
Allograft Function
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