Alteration of p53 gene structure and function in laryngeal squamous cell cancer

1997 ◽  
Vol 254 (S1) ◽  
pp. S133-S137 ◽  
Author(s):  
W. Golusinski ◽  
J. Olofsson ◽  
Z. Szmeja ◽  
K. Szyfter ◽  
W. Szyfter ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Gene Structure ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
P53 Gene ◽  
Structure And Function ◽  
Laryngeal Squamous Cell Cancer ◽  
And Function

scholarly journals Regulation of laryngeal squamous cell cancer progression by the lncRNA RP11‐159K7.2/miR‐206/DNMT3A axis

2020 ◽  
Vol 24 (12) ◽  
pp. 6781-6795
Author(s):  
Xin Wang ◽  
Boyu Yu ◽  
Qianqian Jin ◽  
Junyi Zhang ◽  
Bingrui Yan ◽  
...  
Keyword(s):  
Cancer Progression ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Laryngeal Squamous Cell Cancer

scholarly journals Regulation of laryngeal squamous cell cancer progression by the lncRNA H19/miR-148a-3p/DNMT1 axis

Oncotarget ◽  
2016 ◽  
Vol 7 (10) ◽  
pp. 11553-11566 ◽  
Author(s):  
Tianyi Wu ◽  
Lingmei Qu ◽  
Guoqing He ◽  
Linli Tian ◽  
Liang Li ◽  
...  
Keyword(s):  
Cancer Progression ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Laryngeal Squamous Cell Cancer

scholarly journals HPV-Positive Outcomes in an Access to Care Laryngeal Squamous Cell Cancer Cohort

2011 ◽  
Vol 145 (2_suppl) ◽  
pp. P81-P81
Author(s):  
Josena K. Stephen ◽  
Lu Mei ◽  
Shaleta Harvard ◽  
Glendon M. Gardner ◽  
Kang-Mei Chen ◽  
...  
Keyword(s):  
Access To Care ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Positive Outcomes ◽  
Laryngeal Squamous Cell Cancer

scholarly journals Novel Dysregulated MicroRNAs in Primary Laryngeal Squamous Cell Cancer

2012 ◽  
Vol 3 (2) ◽  
pp. 76-81 ◽  
Author(s):  
Josena K Stephen ◽  
Kang Mei Chen ◽  
Veena Shah ◽  
Vanessa G Schweitzer ◽  
Glendon Gardner ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Differentially Expressed ◽  
Small Noncoding Rnas ◽  
Real Time Quantitative Pcr ◽  
Normal Tissues ◽  
Human Mirnas ◽  
Human Genes ◽  
Laryngeal Squamous Cell Cancer

ABSTRACT Introduction MicroRNAs (miRNAs) are endogenous, small, noncoding RNAs of 17 to 25 nucleotides that regulate approximately 30% of human genes. They are differentially expressed in various types of cancers compared with noncancerous tissues, suggesting that they may have crucial roles in tumorigenesis. The objective of this study was to identify laryngeal squamous cell cancer (LSCC)-specific miRNAs. Materials and methods A retrospective cohort of 10 LSCC and five normal laryngeal squamous epithelium samples were examined using a global miRNA profiling approach (HTG, Tucson, AZ, USA, 800 human miRNAs plus 10 endogenous control miRNAs). The expression status of selected dysregulated miRNAs that were significantly different from normal were verified by real-time quantitative PCR (qPCR). Results Twenty-three of the 800 human miRNAs had significantly different expression levels (p < 0.05) between LSCC and normal tissues. Fifteen of the 23 have not been previously reported in HNSCC and include: miR-663b, miR-663, miR-193b, miR-1291, miR-720, miR-191, miR-1224-3p, miR-214, miR- 1285, miR-1207-5p, miR-483-5p, miR-1225-3p, miR-1228, miR-1280 and miR-638. Consistently upregulated miR-31 and miR- 193b and differentially expressed miR-663b in LSCC were verified by qPCR. Conclusion The 15 novel miRNAs identified in this exploratory study, pending further confirmation and validation, may have clinical utility as LSCC-specific markers. How to cite this article Chen KM, Stephen JK, Havard S Shah V, Gardner G, Schweitzer VG, Worsham MJ. Novel Dysregulated MicroRNAs in Primary Laryngeal Squamous Cell Cancer. Int J Head Neck Surg 2012;3(2):76-81.

scholarly journals Correlation between levels of expression of minichromosome maintenance proteins, Ki-67 proliferation antigen and metallothionein I/II in laryngeal squamous cell cancer

2015 ◽  
Vol 48 (2) ◽  
pp. 635-645 ◽  
Author(s):  
KATARZYNA NOWINSKA ◽  
MAGDALENA CHMIELEWSKA ◽  
ALEKSANDRA PIOTROWSKA ◽  
BARTOSZ PULA ◽  
WOJCIECH PASTUSZEWSKI ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Minichromosome Maintenance ◽  
Ki 67 ◽  
Laryngeal Squamous Cell Cancer

scholarly journals Prognostic values and clinical relationship of TYK2 in laryngeal squamous cell cancer

Medicine ◽  
2021 ◽  
Vol 100 (34) ◽  
pp. e27062
Author(s):  
Lucheng Fang ◽  
Wen Wang ◽  
Licai Shi ◽  
Qinjuan Chen ◽  
Xingwang Rao
Keyword(s):  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Clinical Relationship ◽  
Laryngeal Squamous Cell Cancer ◽  
Relationship Of

scholarly journals Comparison of TMA Technique and Routine Whole Slide Analysis in Evaluation of Proliferative Markers Expression in Laryngeal Squamous Cell Cancer

In Vivo ◽  
2020 ◽  
Vol 34 (6) ◽  
pp. 3263-3270
Author(s):  
URSZULA CIESIELSKA ◽  
ALEKSANDRA PIOTROWSKA ◽  
CHRISTOPHER KOBIERZYCKI ◽  
WOJCIECH PASTUSZEWSKI ◽  
MARZENNA PODHORSKA-OKOLOW ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Proliferative Markers ◽  
Laryngeal Squamous Cell Cancer
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