Reappraisal of bronchial arterial infusion therapy for advanced lung cancer

1990 ◽  
Vol 20 (1) ◽  
pp. 27-35 ◽  
Author(s):  
Yoh Watanabe ◽  
Junzo Shimizu ◽  
Shinya Murakami ◽  
Masayuki Yoshida ◽  
Makoto Tsubota ◽  
...  
Author(s):  
Shinichi Hori ◽  
Tatsuya Nakamura ◽  
Norifumi Kennoki ◽  
Ikuo Dejima ◽  
Atsushi Hori

Abstract Previous reports on transarterial treatment for lung cancer were reviewed. The bronchial arterial infusion therapy has a long history since 1964. Better local control with less doses of anti-neoplastic agents was warranted by trying transarterial administration to lung and mediastinal tumors. It is reported that both primary and metastatic tumors are fed by bronchial or other systemic arteries. The bronchial arterial embolization for hemoptysis has been introduced for clinical practice since 1973. Hemoptysis by not only benign but also malignant diseases has been well controlled by embolization. In recent decades, the technical elements for transarterial treatments have markedly improved. They make it possible to carry out precise procedures of selective catheter insertion to the tumor relating arteries. Current concepts of transarterial treatment, technical aspects and treatment outcomes are summarized. Tentative result from chemo-embolization for advanced lung cancer using recent catheter techniques was also described. It provides favorable local control and survival merits. It is considered that a population of lung cancer patients can benefit from transarterial management using small doses of anti-neoplastic agents, with less complications and less medical costs.


Haigan ◽  
1986 ◽  
Vol 26 (6) ◽  
pp. 623-627
Author(s):  
Masakazu Hasegawa ◽  
Masao Sako ◽  
Shuji Adachi ◽  
Shozo Hirota ◽  
Shuhei Ohtsuki ◽  
...  

1996 ◽  
Vol 87 (6) ◽  
pp. 942-945
Author(s):  
Seiki Imada ◽  
Sadamu Tsukamoto ◽  
Kazunori Hattori ◽  
Naoto Miyanaga ◽  
Katsunori Uchida ◽  
...  

1969 ◽  
Vol 33 (4) ◽  
pp. 581-584
Author(s):  
H Sasaki ◽  
T Wakutani ◽  
S Oda ◽  
Y Yamazaki

1996 ◽  
Vol 2 (4) ◽  
pp. 203-206 ◽  
Author(s):  
Tetsuya Okunaka ◽  
Harubumi Kato ◽  
Chimori Konaka ◽  
Kinya Furukawa ◽  
Masahiko Harada ◽  
...  

Photodynamic therapy (PDT) utilizing Photofrin is proving to be effective for the treatment of early stage lung cancer. However, wider clinical applications of Photofrin as a photosensitizer for various cancers are hampered by potentially serious and prolonged skin photosensitivity. To prevent these side effects and reduce the hospitalization period, we recently gave reduced doses of Photofrin by bronchial arterial infusion. Five patients with endoscopically evaluated minimally invasive carcinoma of the lung were given 0.7 mg/kg of Photofrin by bronchial arterial infusion 48 hr before PDT. Complete remission was obtained in all 5 cases and no case showed skin photosensitivity when exposed to sunlight under careful surveillance at one week after PDT.


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