Morphometric and cytochemical evaluation of clofibrate-induced peroxisomal proliferation in adult rat hepatocytes cultured on floating collagen gels

1988 ◽  
Vol 55 (1) ◽  
pp. 279-285
Author(s):  
Kazunori Furukawa ◽  
Yohichi Mochizuki ◽  
Norimasa Sawada ◽  
Mikio Gotoh ◽  
Hideyuki Tsukada
1980 ◽  
Vol 349 (1) ◽  
pp. 99-110 ◽  
Author(s):  
Joseph T. Spence ◽  
Laura Haars ◽  
Anthony Edwards ◽  
Ann Bosch ◽  
Henry C. Pilot

Author(s):  
M. Kraemer ◽  
J. Foucrier ◽  
J. Vassy ◽  
M.T. Chalumeau

Some authors using immunofluorescent techniques had already suggested that some hepatocytes are able to synthetize several plasma proteins. In vitro studies on normal cells or on cells issued of murine hepatomas raise the same conclusion. These works could be indications of an hepatocyte functionnal non-specialization, meanwhile the authors never give direct topographic proofs suitable with this hypothesis.The use of immunoenzymatic techniques after obtention of monospecific antisera had seemed to us useful to bring forward a better knowledge of this problem. We have studied three carrier proteins (transferrin = Tf, hemopexin = Hx, albumin = Alb) operating at different levels in iron metabolism by demonstrating and localizing the adult rat hepatocytes involved in their synthesis.Immunological, histological and ultrastructural methods have been described in a previous work.


Diabetes ◽  
1991 ◽  
Vol 40 (4) ◽  
pp. 462-464 ◽  
Author(s):  
M. Miralpeix ◽  
J. F. Decaux ◽  
A. Kahn ◽  
R. Bartrons

1981 ◽  
Vol 256 (22) ◽  
pp. 11677-11683
Author(s):  
B. Grandchamp ◽  
D.M. Bissell ◽  
V. Licko ◽  
R. Schmid

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