Studies on the calcium antagonistic action of tetrandrine: XI: Effects of tetrandrine and verapamil on contractility and oxygen consumption in heart muscle

1985 ◽  
Vol 5 (3) ◽  
pp. 135-138
Author(s):  
Wei-xing Yao ◽  
Da-chao Fang ◽  
Guo-jin Xia ◽  
Ming-xing Jiang
Keyword(s):  
Oxygen Consumption ◽  
Heart Muscle ◽  
Antagonistic Action

In vitro Measurements of Oxygen Consumption of Human Heart Muscle

Nature ◽  
1963 ◽  
Vol 197 (4869) ◽  
pp. 802-803
Author(s):  
J. N. NORMAN ◽  
T. A. DOUGLAS ◽  
G. SMITH ◽  
C. HENDERSON
Keyword(s):  
Oxygen Consumption ◽  
Heart Muscle ◽  
Human Heart ◽  
In Vitro Measurements

Effects of epinephrines on metabolism and contraction of cat papillary muscle

1964 ◽  
Vol 206 (3) ◽  
pp. 525-530 ◽  
Author(s):  
Kwang Soo Lee ◽  
Dai Hyun Yu
Keyword(s):  
Oxygen Consumption ◽  
Papillary Muscle ◽  
Heart Muscle ◽  
Mechanical Efficiency ◽  
Metabolic Efficiency ◽  
Metabolic State ◽  
Cat Papillary Muscle ◽  
Sympathomimetic Amines ◽  
Tissue Contents

The change of metabolic state and contractility of heart induced by epinephrine and norepinephrine was studied in in vitro preparations of cat papillary muscle. The oxygen consumption, glycogen content, energy-rich phosphate content, and contractility of muscles were measured simultaneously whenever possible by techniques described previously. It was found that these amines did not change significantly the tissue contents of energy-rich phosphate compounds and glycogen in these conditions. The oxygen consumption and contractility of muscles were markedly influenced by the sympathomimetic amines. The change of metabolic efficiency as measured by the ratio, contractile tension : total Qo2, following the administration of these amines were dependent on the condition of heart muscles at the time of administration of these agents. Thus, when muscles were fresh, the metabolic efficiency was not significantly changed by the amines. However, when muscles were in the hypodynamic state, the amines were found to increase the metabolic efficiency of the heart muscle significantly. This suggests that the metabolic state of heart muscle should be taken into consideration whenever the influence of these sympathomimetic amines on the mechanical efficiency of heart is investigated.

Effect of stretch on O2 consumption of resting and active frog sartorius muscle

1962 ◽  
Vol 203 (4) ◽  
pp. 731-734 ◽  
Author(s):  
W. J. Whalen ◽  
L. C. Collins ◽  
H. Berry
Keyword(s):  
Oxygen Consumption ◽  
Heart Muscle ◽  
Heat Liberation ◽  
Sartorius Muscle ◽  
O2 Consumption ◽  
Frog Sartorius Muscle ◽  
Resting Tension ◽  
Resting Muscle ◽  
Frog Sartorius

Oxygen consumption and resting and developed tension were measured simultaneously while the length of the muscle was increased by known increments. The Qo2 of resting muscle increased about 1% for each 1% extension beyond the relaxed length. Both resting tension and length were directly related to Qo2. In a stimulated muscle, Qo2 and frequency of contraction showed a highly significant correlation. The Qo2 of a stimulated muscle increased as the length and total tension (developed plus resting) increased. Neither Qo2 nor the increment in Qo2 above the resting level correlated significantly with developed tension. These latter findings differ from the results predicted from heat-liberation experiments. The results found here are not markedly different from those we found in heart muscle.

Oxygen Consumption of Post-Mortem Human Heart Muscle.

1958 ◽  
Vol 99 (1) ◽  
pp. 246-247
Author(s):  
W. C. Ullrick ◽  
E. A. Lentini ◽  
S. C. Sommers
Keyword(s):  
Oxygen Consumption ◽  
Heart Muscle ◽  
Human Heart ◽  
Post Mortem

Changes in oxygen consumption of isolated heart muscle from animals treated with cardio-active drugs

1985 ◽  
Vol 5 (1) ◽  
pp. 20-22
Author(s):  
Liu Gui-de ◽  
Yu Wan-li ◽  
Wang Cong-ming
Keyword(s):  
Oxygen Consumption ◽  
Heart Muscle ◽  
Isolated Heart

The effect of hypothermia and anoxia upon oxygen consumption and contractility of human and rat heart muscle

1970 ◽  
Vol 79 (1) ◽  
pp. 88-95 ◽  
Author(s):  
Argie Tsifutis ◽  
Robert M. Burton ◽  
David Goldring
Keyword(s):  
Oxygen Consumption ◽  
Heart Muscle ◽  
Rat Heart

Some factors influencing O2 consumption of isolated heart muscle

1960 ◽  
Vol 198 (6) ◽  
pp. 1153-1156 ◽  
Author(s):  
William J. Whalen
Keyword(s):  
Oxygen Consumption ◽  
Heart Muscle ◽  
Isolated Heart ◽  
O2 Consumption ◽  
Starling’S Law ◽  
Factors Influencing ◽  
Mammalian Myocardium ◽  
Per Se ◽  
Relationship Of

Oxygen consumption and resting and developed tension in isolated strips of mammalian myocardium were simultaneously measured in specially constructed chambers. In a resting preparation the O2 consumption increased significantly as the length of the muscle was increased. The evidence suggests that the augmented Qo2 (µl/mg dry wt/hr.) is largely a result of the lengthening, per se, and is not due to the maintenance of tension. In the beating preparation, variations in rate and length accounted for most of the change in the O2 uptake, tension being a less significant factor. The possible relationship of these findings to ‘Starling's law of the heart’ is discussed.

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