Specialized function of the nonclassical MHC class I molecule Hmt: A specific receptor for N-formylated peptides

1991 ◽  
Vol 10 (3-4) ◽  
pp. 365-375 ◽  
Author(s):  
Said M. Shawar ◽  
John R. Rodgers ◽  
Richard G. Cook ◽  
Robert R. Rich
Keyword(s):  
Mhc Class I ◽  
Class I ◽  
Specific Receptor ◽  
Mhc Class I Molecule ◽  
Specialized Function ◽  
Nonclassical Mhc

scholarly journals Erratum: Recognition of the nonclassical MHC class I molecule H2-M3 by the receptor Ly49A regulates the licensing and activation of NK cells

2013 ◽  
Vol 14 (4) ◽  
pp. 413-413
Author(s):  
Daniel M Andrews ◽  
Lucy C Sullivan ◽  
Nikola Baschuk ◽  
Christopher J Chan ◽  
Richard Berry ◽  
...  
Keyword(s):  
Nk Cells ◽  
Mhc Class I ◽  
Class I ◽  
Mhc Class I Molecule ◽  
Nonclassical Mhc

scholarly journals The Nonclassical MHC Class I Molecule Qa-1 Forms Unstable Peptide Complexes

2004 ◽  
Vol 172 (3) ◽  
pp. 1661-1669 ◽  
Author(s):  
Taku Kambayashi ◽  
Jennifer R. Kraft-Leavy ◽  
Joseph G. Dauner ◽  
Barbara A. Sullivan ◽  
Oskar Laur ◽  
...  
Keyword(s):  
Mhc Class I ◽  
Class I ◽  
Mhc Class I Molecule ◽  
Peptide Complexes ◽  
Nonclassical Mhc

scholarly journals Qa-2–Dependent Selection of Cd8α/α T Cell Receptor α/β+ Cells in Murine Intestinal Intraepithelial Lymphocytes

2000 ◽  
Vol 192 (10) ◽  
pp. 1521-1528 ◽  
Author(s):  
Gobardhan Das ◽  
Dina S. Gould ◽  
Mathew M. Augustine ◽  
Gladis Fragoso ◽  
Edda Scitto ◽  
...  
Keyword(s):  
T Cells ◽  
Mhc Class I ◽  
Antigen Processing ◽  
Intraepithelial Lymphocytes ◽  
Class I ◽  
Β Cells ◽  
Double Knockout ◽  
Intestinal Intraepithelial Lymphocytes ◽  
Mhc Class I Molecule ◽  
Nonclassical Mhc

Murine intestinal intraepithelial lymphocytes (iIELs) are made up of a heterogeneous mix of T cells with unique phenotypes. Whereas CD8+ T cells in peripheral lymphoid organs use CD8α/β and are selected on MHC class Ia molecules, a majority of iIELs use CD8α/α. Here, we report that the presence of CD8α/α TCR-α/β cells in iIELs is independent of classical MHC class I molecules Kb and Db, as illustrated by their presence in Kb/Db double-knockout mice and in mice lacking a nonclassical MHC class I molecule, CD1d. Most strikingly, their presence is decreased by ∼70% in mice lacking transporter associated with antigen processing (TAP). The TAP-dependent nonclassical MHC class I molecule Qa-2 is strongly implicated in the presence of these cells, as inferred from the low numbers of CD8α/α TCR-α/β T cells in mice deficient in Qa-2 genes. Second, a Qa-2–transgenic mouse made in a Qa-2− strain showed an increase in the numbers of CD8α/α cells among its iIELs. Thus, the presence of CD8α/α TCR-α/β cells in iIELs is mainly dependent on the nonclassical MHC class I molecule Qa-2.

scholarly journals A Soluble Isoform of the Rhesus Monkey Nonclassical MHC Class I Molecule Mamu-AG Is Expressed in the Placenta and the Testis

2002 ◽  
Vol 169 (2) ◽  
pp. 673-683 ◽  
Author(s):  
Andy F. Ryan ◽  
Richard L. Grendell ◽  
Daniel E. Geraghty ◽  
Thaddeus G. Golos
Keyword(s):  
Rhesus Monkey ◽  
Mhc Class I ◽  
Class I ◽  
Mhc Class I Molecule ◽  
Nonclassical Mhc

scholarly journals Placental expression of the nonclassical MHC class I molecule Mamu-AG at implantation in the rhesus monkey

2000 ◽  
Vol 97 (16) ◽  
pp. 9104-9109 ◽  
Author(s):  
I. I. Slukvin ◽  
D. P. Lunn ◽  
D. I. Watkins ◽  
T. G. Golos
Keyword(s):  
Rhesus Monkey ◽  
Mhc Class I ◽  
Class I ◽  
Mhc Class I Molecule ◽  
Nonclassical Mhc

scholarly journals The Murine Liver-Specific Nonclassical MHC Class I Molecule Q10 Binds a Classical Peptide Repertoire

2000 ◽  
Vol 164 (4) ◽  
pp. 1906-1915 ◽  
Author(s):  
Francesca Zappacosta ◽  
Piotr Tabaczewski ◽  
Kenneth C. Parker ◽  
John E. Coligan ◽  
Iwona Stroynowski
Keyword(s):  
Mhc Class I ◽  
Class I ◽  
Mhc Class I Molecule ◽  
Murine Liver ◽  
Nonclassical Mhc
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