Arterial oxygen saturation following premedication in children with cyanotic congenital heart disease

A retinopathy consisting of dilated, tortuous retinal blood vessels and, in some patients, papilledema may occur in cyanotic congenital heart disease (CHD). Of 83 patients with cyanotic CHD examined ophthalmologically, 52 exhibited some degree of the retinopathy, and 12 had papilledema. The severity of the fundus changes was closely related to the patient's arterial oxygen saturation and hematocrit and bore no relationship to arterial Pco2, pH, central venous pressure, type of cardiac malformation, or the patient's age.

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The arterial oxygen saturation in cyanotic types of congenital heart disease

American Heart Journal ◽

10.1016/0002-8703(49)90575-x ◽

1949 ◽

Vol 37 (2) ◽

pp. 301-302

Author(s):

Arkless

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Oxygen Saturation ◽

Congenital Heart ◽

Arterial Oxygen Saturation ◽

Arterial Oxygen

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Low peripheral oxygen saturation as a risk factor for brain abscess in children with cyanotic congenital heart disease

Paediatrica Indonesiana ◽

10.14238/pi58.5.2018.252-6 ◽

2018 ◽

Vol 58 (5) ◽

pp. 252-6

Author(s):

Nadia Qoriah Firdausy ◽

Indah Kartika Murni ◽

Agung Triono ◽

Noormanto Noormanto ◽

Sasmito Nugroho

Keyword(s):

Congenital Heart Disease ◽

Risk Factor ◽

Heart Disease ◽

Oxygen Saturation ◽

Brain Abscess ◽

Congenital Heart ◽

Significant Risk ◽

Cyanotic Congenital Heart Disease ◽

Arterial Oxygen ◽

Peripheral Oxygen Saturation

Background Brain abscess is a severe infection of brain parenchyma, which occurs in 25-46% of cases of uncorrected cyanotic congenital heart disease. Low arterial oxygen saturation is the main risk factor for brain abscess in children with cyanotic congenital heart disease, however, the arterial oxygen saturation test is invasive and not routinely done in our setting. Objective To evaluate low peripheral oxygen saturation as a risk factor for brain abscess in children with cyanotic congenital heart disease. Methods We conducted a matched, case-control study at Sardjito Hospital, Yogyakarta for children aged less than 18 years with cyanotic congenital heart disease, from 2010-2016. Case subjects were children with brain abscess complications. The control group had only cyanotic congenital heart disease, and were matched for age and sex to the case group. During hospitalization due to the brain abscess complication in the case group, data regarding peripheral oxygen saturation, polycythemia, pneumonia, sepsis, dental caries and restricted pulmonary blood flow were collected and compared between both groups. Results During the study period, 18 children with cyanotic congenital heart disease had brain abscesses. This group was compared to the control group of 36 children. Bivariate analysis revealed that the lowest level of peripheral oxygen saturation (OR 0.92; 95%CI 0.85 to 0.98; P=0.02) and dental caries (OR 3.3; 95%CI 1.01 to 11.18; P=0.04) were significant risk factors for brain abscess. However, in the multivariate analysis, the only statistically significant risk factor associated with brain abscess was the lowest level of peripheral oxygen saturation (OR 0.92; 95%CI 0.86 to 0.99; P=0.04). Conclusion Low peripheral oxygen saturation is a significant risk factor for brain abscess development in children with cyanotic congenital heart disease. A decrease of 1% peripheral oxygen saturation may increase the risk of brain abscess by 8%.

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Comparative study of pulse oximetry, physical examination and echocardiography results in the diagnosis of congenital heart defects in neonates in the first 24 hours of life

Journal of Shahid Sadoughi University of Medical Sciences ◽

10.18502/ssu.v29i5.6776 ◽

2021 ◽

Author(s):

Fatemeh Amiri Simkouii ◽

Maryam Jamshidi ◽

Mostafa Behjati Ardakani ◽

Farzaneh Toosi ◽

Mohammad Reza Alipour ◽

...

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Physical Examination ◽

Oxygen Saturation ◽

Pulse Oximetry ◽

Congenital Heart ◽

Statistical Tests ◽

Arterial Oxygen Saturation ◽

Screening Method ◽

Arterial Oxygen

Introduction: Congenital heart disease is the most common congenital anomaly. About 50% of Neonates with congenital heart disease are asymptomatic in the first few days of life and are not diagnosed on initial examination. Pulse oximetry is a non-invasive method that can show the percentage of oxygen saturation in the blood and congenital heart disease. Methods: This was a descriptive cross-sectional study and the sampling method was census. Echocardiography was performed for all neonates with spo2 less than 95% and also neonates who were diagnosed with a problem by a cardiologist. After collecting the samples, the results obtained from pulse oximetry, physical examination and echocardiography were analyzed using SPSS software version 16 and statistical tests of Kolmogorov-Smirnov normality and Spearman correlation. Was investigated. Results: In pulse oximetry evaluation, 1.9% of neonates had spo2 (arterial oxygen saturation) less than 95%. 1.7% of neonates had heart problems in physical examination and 2.12% of neonates had heart problems in echocardiography. The highest correlation between pulse oximetry and echocardiography was 0.917. Conclusion: Considering the diagnostic importance of congenital heart diseases and their impact on a person's life, it is recommended that pulse oximetry be added to physical examinations at birth as a screening method for heart disease.

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