STUDYING PAIN RELIEF WITH NON-STEROIDAL ANTI-INFLAMMATORY DRUGS

InPharma ◽  
1983 ◽  
Vol 406 (1) ◽  
pp. 7-8
1994 ◽  
Vol 84 (7) ◽  
pp. 348-354 ◽  
Author(s):  
MB Jennings

Osteoarthritis is the most common joint disease and the second highest ranking cause of disability in the US. Osteoarthritis commonly affects the hands, wrists, spine, knees, and feet. One of the mainstays of treatment for osteoarthritis is the use of nonsteroidal anti-inflammatory drugs. While there have been controlled comparison studies of the various nonsteroidal anti-inflammatory drugs, these have been limited to osteoarthritis of the hands, spine, and hip. This study was a randomized, double-blind, parallel study of 8 weeks' duration comparing piroxicam (Feldene, 20 mg daily) to naproxen (Naprosyn, 1,000 mg daily) in the treatment of osteoarthritis of the foot in 45 patients. Both groups experienced significant pain relief and improvement of mobility.


Livestock ◽  
2020 ◽  
Vol 25 (5) ◽  
pp. 202-209
Author(s):  
Jon Reader ◽  
Tom Angel ◽  
Imogen Rogers

The importance of pain relief in farm animals has never been further up the agenda for modern food production and farm animal practice. This has been driven by increased awareness amongst farmers, veterinary surgeons and consumers. This article looks at the practical use of non-steroidal anti-inflammatory drugs (NSAIDs) in farm animal practice for both adults and youngstock. The basic mode of action of NSAIDs is discussed and some of the evidence base that has been growing over the use of NSAIDs in cattle. It also highlights some of the present requirements of some of the retailers and auditing bodies.


2021 ◽  
Vol 20 (4) ◽  
pp. 96-101
Author(s):  
M. Ronis ◽  
◽  
D. Katovich ◽  
G. Sumeraga ◽  
◽  
...  

Tonsillectomy, cryptolysis of the palatine tonsils, and removal of various formations in the pharyngeal region are the most common elective operations in otorhinolaryngology. Pain in the early postoperative period is still the most frequent complication after these procedures, which can adversely affect the patient’s daily life. Considering the potential analgesic and anti-inflammatory effect of essential oil preparations, as well as their ability to be easily applied locally to the affected mucosal surface, it is worth considering their use to reduce pain and dysphagia in the postoperative period in the upper respiratory tract. The study involved 77 patients who were randomly divided into 2 groups: patients taking a drug containing combined natural essential oils (CNEO) and patients taking a placebo. In the course of the study, a questionnaire was used, according to which patients were interviewed immediately after the operation, then on the 3rd and 10th postoperative days. The results of the study show that the drug does not directly reduce postoperative pain in the pharynx, but in patients in the group with the drug based on combined essential oils, the frequency of taking non-steroidal anti-inflammatory drugs (NSAIDs) was less than in patients in the placebo group, which indirectly proves the effectiveness of the drug based on combined essential oils. Given the fact that the frequency of NSAID use is lower in the CPNEM group, it can be assumed that the study drug reduces the risk of side effects caused by NSAID use, and can also be an alternative method of pain relief for patients who are contraindicated in NSAIDs.


1992 ◽  
Vol 26 (4) ◽  
pp. 241-255 ◽  
Author(s):  
Jane H. Liles ◽  
P. A. Flecknell

The data concerning the use of non-steroidal anti-inflammatory drugs (NSAIDs) and evidence for their efficacy in laboratory rats and mice are reviewed. This information is then extrapolated to clinical situations and dose rates that take account of ulcerogenic side effects are recommended. NSAIDs have the potential to be a very useful group of analgesics and should always be considered when attempting to provide pain relief in laboratory animals.


Sign in / Sign up

Export Citation Format

Share Document