Disulfiram inhibits inflammation and fibrosis in a rat unilateral ureteral obstruction model by inhibiting gasdermin D cleavage and pyroptosis

2021 ◽  
Author(s):  
Yu Zhang ◽  
Ruicheng Zhang ◽  
Xiaohu Han
Keyword(s):  
Ureteral Obstruction ◽  
Unilateral Ureteral Obstruction

Effects of valsartan on renal interstitium fibrosis in rats after unilateral ureteral obstruction

2010 ◽  
Vol 30 (3) ◽  
pp. 278-282
Author(s):  
Jian-song ZHOU ◽  
Gang CHEN ◽  
Ye-qu SHEN ◽  
Mei WU ◽  
Li-qun HE
Keyword(s):  
Ureteral Obstruction ◽  
Unilateral Ureteral Obstruction ◽  
Renal Interstitium

Evaluation of preoperative ultrasonographic parameters to predict renal recovery in long-term survivors after treatment of feline ureteral obstructions: 2012–2019

2021 ◽  
pp. 1098612X2110236
Author(s):  
Elisa P McEntee ◽  
Allyson C Berent ◽  
Chick Weisse ◽  
Alexandre Le Roux ◽  
Kenneth Lamb
Keyword(s):  
Serum Creatinine ◽  
Ultrasound Imaging ◽  
Ureteral Obstruction ◽  
Unilateral Ureteral Obstruction ◽  
Biochemical Data ◽  
Preoperative Imaging ◽  
Long Term Outcome ◽  
Preoperative Ultrasound ◽  
Imaging Characteristics

Objectives The aim of this study was to determine whether preoperative ultrasound imaging characteristic(s) in cats suffering from unilateral benign ureteral obstructions are predictive of outcome after successful renal decompression with a subcutaneous ureteral bypass (SUB) device. Methods This was a retrospective study of 37 cats with unilateral, benign ureteral obstruction. Preoperative imaging characteristics (including renal pelvis diameter, parenchymal thickness [transverse plane], renal length and pelvic size:overall renal size) and biochemical data were evaluated for all cats diagnosed with a unilateral ureteral obstruction treated with a SUB device. Any patient with bilateral obstructions or documented bacteriuria/infection in the data collection period was excluded. All patients were followed between 3 and 6 months postoperatively to obtain postoperative biochemical data. Long-term outcome was defined as serum creatinine concentration at 3–6 months postoperatively. Results No preoperative imaging characteristics or biochemical findings were found to be significantly associated with long-term serum creatinine concentrations. The length of the kidney was found to be associated with change in blood urea nitrogen and creatinine with decompression but not with long-term renal values. Conclusions and relevance In this study, long-term renal function based on preoperative ultrasound imaging findings could not be predicted in cats with unilateral ureteral obstruction, regardless of the severity of the biochemical parameters, renal pelvic dilation (large or small pelvis), kidney size or thickness of renal parenchyma assessed.

The antifibrotic and anti-inflammatory effects of icariin on the kidney in a unilateral ureteral obstruction mouse model

Phytomedicine ◽  
2019 ◽  
Vol 59 ◽  
pp. 152917 ◽  
Author(s):  
Hsin‐An Chen ◽  
Chang-Mu Chen ◽  
Siao-Syun Guan ◽  
Chih-Kang Chiang ◽  
Cheng-Tien Wu ◽  
...  
Keyword(s):  
Mouse Model ◽  
Ureteral Obstruction ◽  
Unilateral Ureteral Obstruction ◽  
Anti Inflammatory

scholarly journals Activation of Erk1/2 and Akt following unilateral ureteral obstruction

2008 ◽  
Vol 74 (2) ◽  
pp. 196-209 ◽  
Author(s):  
Ana B. Rodríguez-Peña ◽  
Maria T. Grande ◽  
Nélida Eleno ◽  
Miguel Arévalo ◽  
Carmen Guerrero ◽  
...  
Keyword(s):  
Ureteral Obstruction ◽  
Unilateral Ureteral Obstruction

scholarly journals SAMP1/Sku as a Murine Model for Tubulointerstitial Nephritis: a Study Using Unilateral Ureteral Obstruction

2005 ◽  
Vol 54 (1) ◽  
pp. 53-60 ◽  
Author(s):  
Akira YABUKI ◽  
Michie MAEDA ◽  
Mitsuharu MATSUMOTO ◽  
Ryozo KAMIMURA ◽  
Taku MASUYAMA ◽  
...  
Keyword(s):  
Murine Model ◽  
Ureteral Obstruction ◽  
Tubulointerstitial Nephritis ◽  
Unilateral Ureteral Obstruction

Unilateral Ureteral Obstruction Secondary to Rupture of Liver Echinococcal Cyst

1992 ◽  
Vol 148 (6) ◽  
pp. 1888-1889
Author(s):  
Oz M. Shapira ◽  
Dan Simon ◽  
Harry Rothstein ◽  
Eitan Mor ◽  
Reuven Pfeffermann
Keyword(s):  
Ureteral Obstruction ◽  
Unilateral Ureteral Obstruction ◽  
Echinococcal Cyst
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