AbstractWe study $n$-vertex $d$-dimensional polytopes with at most one nonsimplex facet with, say, $d+s$ vertices, called almost simplicial polytopes. We provide tight lower and upper bound theorems for these polytopes as functions of $d,n$, and $s$, thus generalizing the classical Lower Bound Theorem by Barnette and the Upper Bound Theorem by McMullen, which treat the case where $s=0$. We characterize the minimizers and provide examples of maximizers for any $d$. Our construction of maximizers is a generalization of cyclic polytopes, based on a suitable variation of the moment curve, and is of independent interest.