Synthesis, characterization, and DNA cleavage study of dehydroacetic acid based tridentate Schiff’s base and its metal complexes of first transition series

2014 ◽  
Vol 23 (9) ◽  
pp. 4060-4069 ◽  
Author(s):  
R. Pal ◽  
V. Kumar ◽  
A. K. Gupta ◽  
V. Beniwal ◽  
G. K. Gupta
Keyword(s):  
Metal Complexes ◽  
Dna Cleavage ◽  
Schiff’S Base ◽  
Dehydroacetic Acid ◽  
Transition Series

DNA cleavage mechanism by metal complexes of Cu(II), Zn(II) and VO(IV) with a schiff-base ligand

Biochimie ◽  
2021 ◽  
Vol 186 ◽  
pp. 43-50
Author(s):  
María R. Rodríguez ◽  
Martín J. Lavecchia ◽  
Beatriz S. Parajón-Costa ◽  
Ana C. González-Baró ◽  
María R. González-Baró ◽  
...  
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Schiff Base Ligand ◽  
Dna Cleavage

Synthesis, characterization, antimicrobial, and DNA cleavage studies of metal complexes of coumarin Schiff bases

2010 ◽  
Vol 20 (4) ◽  
pp. 493-502 ◽  
Author(s):  
Mohammedshafi A. Phaniband ◽  
Shreedhar D. Dhumwad ◽  
Shashikanth R. Pattan
Keyword(s):  
Metal Complexes ◽  
Schiff Bases ◽  
Dna Cleavage

Metal-ion-dependent oxidative DNA cleavage by transition metal complexes of a new water-soluble salen derivative

1996 ◽  
Vol 63 (4) ◽  
pp. 265-272 ◽  
Author(s):  
Subhrangsu S. Mandal ◽  
N. Vinay Kumar ◽  
Umesh Varshney ◽  
Santanu Bhattacharya
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Dna Cleavage ◽  
Metal Ion ◽  
Water Soluble ◽  
Oxidative Dna Cleavage

Synthesis, structural characterisation, bio-potential efficiency and DNA cleavage applications of nicotinamide metal complexes

2013 ◽  
Vol 1040 ◽  
pp. 192-205 ◽  
Author(s):  
C. Surendra Dilip ◽  
V. Siva Kumar ◽  
S. John Venison ◽  
I. Vetha potheher ◽  
D. Rajalaxmi (a) Subahashini
Keyword(s):  
Metal Complexes ◽  
Dna Cleavage ◽  
Structural Characterisation ◽  
Potential Efficiency

scholarly journals Medicinal Utility of Some Schiff Bases and their Complexes with First Transition Series Metals: A Review

2021 ◽  
Vol 37 (5) ◽  
pp. 1051-1061
Author(s):  
Tahmeena Khan ◽  
Saima Zehra ◽  
Almas Alvi ◽  
Umama Fatima ◽  
Alfred J. Lawrence
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Present Review ◽  
Potential Drug ◽  
Drug Candidates ◽  
Transition Series ◽  
Low Toxicity ◽  
Activity Enhancement

Schiff based ligands and their complexes have emerged as potential drug candidates. Owing to their excellent chelating tendency, they easily coordinate with transition metals which have vacant orbitals. Transition metal complexes have several advantages because of their better acceptability and low toxicity in biological systems. These metals also serve as micronutrients and as co-factors of various metallo-enzymes which justifies the need of their designing and synthesis. Many modifications have been suggested in the ligand moiety for the purpose of activity enhancement and some of them have been described in the present review. These modifications have enhanced better potency against a number of diseases and resulting in low toxicity and better solubility in vivo. The transition metal complexes with Schiff based complexes have exhibited an array of activities including anticancer, antioxidant and antimicrobial. Their analytical applications have also been reported. The present review summarizes some of the recent advances in the field of synthesis and designing of new Schiff based complexes particularly with first transition series metals and their medicinal applications.

The formation constants of some metal complexes with 3-Acetyl-4-hydroxycoumarin, dehydroacetic acid, and their oximes

1971 ◽  
Vol 24 (5) ◽  
pp. 925 ◽  
Author(s):  
GCS Manku
Keyword(s):  
Metal Complexes ◽  
Sodium Perchlorate ◽  
Formation Constants ◽  
Ionic Concentration ◽  
Dehydroacetic Acid ◽  
Nitrogen Donors ◽  
Oxygen Donors

The formation constants (K1, K2, and β2) of the complexes of 3-acetyl-4- hydroxycoumarin (ahc) and dehydroacetic acid (dha) and their respective oximes, ahco and dhao, with iron(II), cobalt(II), nickel(II), copper(II), zinc(II), calcium(II), magnesium(II), cadmium(II), dioxouranium(VI), iron(III), aluminium(III), scandium(III), indium(III), yttrium(III), and lanthanon(III) ions (lanthanum to lutetium inclusive with the exception of promethium) have been determined pH-metrically at 35� in 50% v/v aqueous dioxan medium with 0.100M sodium perchlorate as the constant ionic concentration, using Calvin and Wilson's pH-metric technique. The trends in the formation constants of these complexes are discussed. It is observed that, except in the case of Co2+, Ni2+, and Cu2+ ions, for which chelation through nitrogen donors is more favoured, all other ions prefer coordination through oxygen donors.

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