Protective effects of apigenin, apigenin-8-sulfonate, and apigenin-3′, 8-disulfonate on d-galactosamine-induced acute liver damage in mice

2020 ◽  
Vol 29 (10) ◽  
pp. 1867-1873
Author(s):  
Xin-Bin Yang ◽  
Yu Huang
Keyword(s):  
Liver Damage ◽  
Protective Effects ◽  
Acute Liver Damage

Hepatoprotective Effect of Phyllanthus in Taiwan on Acute Liver Damage Induced by Carbon Tetrachloride

2006 ◽  
Vol 34 (03) ◽  
pp. 471-482 ◽  
Author(s):  
Chao-Ying Lee ◽  
Wen-Huang Peng ◽  
Hao-Yuan Cheng ◽  
Fei-Na Chen ◽  
Ming-Tsung Lai ◽  
...  
Keyword(s):  
Liver Damage ◽  
Reduced Glutathione ◽  
Protective Effects ◽  
Acute Liver Damage ◽  
Glutamate Pyruvate Transaminase ◽  
Methanolic Extracts ◽  
Antioxidant Agents ◽  
Serum Glutamate Pyruvate Transaminase ◽  
Glutamate Pyruvate ◽  
Serum Glutamate

The effect of oral administration of Phyllanthus methanolic extracts (PME) (i.e. P. acidus, P. emblica, P. myrtifolius, P. multiflorus, P. amarus, P. debilis, P. embergeri, P. hookeri, P. tenellus, P. urinaria L.s. nudicarpus, P. urinaria L.s. urinaria) or gallic acid (GA) on the progression of acute liver damage induced by CCl 4 in rats was examined by morphological and biochemical methods. P. acidus, P. urinaria L.s. urinaria, GA at a dose of 0.5 g/kg, and P. emblica, P. urinaria L.s. nudicarpus at a dose of 1.0 g/kg attenuated CCl 4-induced increase in serum glutamate-oxalate-transaminase (GOT). P. acidus, P. urinaria L.s. nudicarpus, P. urinaria L.s. urinaria, GA at a dose of 0.5 g/kg, and P. emblica, P. amarus, P. hookeri, P. tenellus at a dose of 1.0 g/kg attenuated CCl 4-induced increase in serum glutamate-pyruvate-transaminase (GPT). Concurrently, P. acidus, P. multiflorus, P. embergeri, P. hookeri, P. tenellus and P. urinaria L.s. urinaria elevated the activity of liver reduced glutathione peroxidase (GSH-Px). Since the protective effects of P. acidus, P. emblica, P. myrtifolius, P. embergeri, P. urinaria L.s. nudicarpus, P. urinaria L.s. urinaria and GA correlate with a reduction in liver infiltration and focal necrosis observed using histological methods, these data demonstrate that P. acidus and P. urinaria L.s. urinaria are hepatoprotective and antioxidant agents.

scholarly journals Protective Effects of Melatonin on CCl4-induced Acute Liver Damage and Testicular Toxicity in Rats

2018 ◽  
Vol 80 (6) ◽  
Author(s):  
Tian-Yue Wang ◽  
Yan Li ◽  
Xiao Wu ◽  
Xiao Long Yang ◽  
Yaguang Wang ◽  
...  
Keyword(s):  
Liver Damage ◽  
Testicular Toxicity ◽  
Protective Effects ◽  
Acute Liver Damage

scholarly journals Protective Effects of Co-Enzyme Q10 on Thioacetamide-Induced Acute Liver Damage and Its Correlation With Behavioral, Biochemical, and Pathological Factors

2016 ◽  
Vol 18 (8) ◽  
Author(s):  
Soheil Ashkani-Esfahani ◽  
Fereshteh Bagheri ◽  
Yasaman Emami ◽  
Elmira Esmaeilzadeh ◽  
Negar Azarpira ◽  
...  
Keyword(s):  
Liver Damage ◽  
Protective Effects ◽  
Acute Liver Damage

scholarly journals Protective effects of quercetin on thioacetamide-induced acute liver damage and its related biochemical and pathological alterations

2016 ◽  
Vol 28 (3) ◽  
pp. 123 ◽  
Author(s):  
Fereshteh Bagheri ◽  
Soheil Ashkani-Esfahani ◽  
Negar Azarpira ◽  
Elmira Esmaeilzadeh ◽  
Yasaman Emami ◽  
...  
Keyword(s):  
Liver Damage ◽  
Protective Effects ◽  
Acute Liver Damage

Effect of preliminary fasting on development of acute liver damage by D-galactosamine in rats

1989 ◽  
Vol 107 (1) ◽  
pp. 38-41
Author(s):  
D. Adzharov ◽  
N. Donchev ◽  
M. Kerimova ◽  
E. Naidenova ◽  
B. Borov ◽  
...  
Keyword(s):  
Liver Damage ◽  
Acute Liver Damage
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