Efficient dose-dependent and time-dependent protein transduction of pancreatic carcinoma cells in vitro and in vivo using purified VP22-EGFP fusion protein

2003 ◽  
Vol 81 (3) ◽  
pp. 205-213 ◽  
Author(s):  
Lars Boenicke ◽  
Kang Chu ◽  
Regina Pauls ◽  
Claudia Tams ◽  
Marie-Luise Kruse ◽  
...  
Keyword(s):  
Fusion Protein ◽  
Pancreatic Carcinoma ◽  
Carcinoma Cells ◽  
Time Dependent ◽  
Protein Transduction ◽  
Egfp Fusion Protein ◽  
Dependent Protein ◽  
Dose Dependent

A marginal anticancer effect of regorafenib on pancreatic carcinoma cells in vitro, ex vivo, and in vivo

2017 ◽  
Vol 390 (11) ◽  
pp. 1125-1134 ◽  
Author(s):  
Barbara Mayer ◽  
Svetlana Karakhanova ◽  
Nathalie Bauer ◽  
Li Liu ◽  
Yifan Zhu ◽  
...  
Keyword(s):  
Pancreatic Carcinoma ◽  
Ex Vivo ◽  
Carcinoma Cells ◽  
Anticancer Effect

scholarly journals The ATP-Competitive mTOR Inhibitor INK128 Enhances In Vitro and In Vivo Radiosensitivity of Pancreatic Carcinoma Cells

2013 ◽  
Vol 20 (1) ◽  
pp. 110-119 ◽  
Author(s):  
Thomas J. Hayman ◽  
Amy Wahba ◽  
Barbara H. Rath ◽  
Heekyong Bae ◽  
Tamalee Kramp ◽  
...  
Keyword(s):  
Pancreatic Carcinoma ◽  
Mtor Inhibitor ◽  
Carcinoma Cells

scholarly journals Vitamin D receptors and anti-proliferative effects of vitamin D derivatives in human pancreatic carcinoma cells in vivo and in vitro

1997 ◽  
Vol 76 (8) ◽  
pp. 1017-1020 ◽  
Author(s):  
KW Colston ◽  
SY James ◽  
EA Ofori-Kuragu ◽  
L Binderup ◽  
AG Grant
Keyword(s):  
Vitamin D ◽  
Pancreatic Carcinoma ◽  
Carcinoma Cells ◽  
Vitamin D Receptors

scholarly journals Small interfering RNAs targeting mutant K-ras inhibit human pancreatic carcinoma cells growth in vitro and in vivo

2006 ◽  
Vol 5 (12) ◽  
pp. 1693-1698 ◽  
Author(s):  
Hong Zhu ◽  
Zhi Yong Liang ◽  
Xin Yu Ren ◽  
Tong Hua Li
Keyword(s):  
Pancreatic Carcinoma ◽  
Carcinoma Cells ◽  
Small Interfering Rnas

3,3′,5′-Triiodothyronine inhibits ontogenetic development of iodothyronine-5′-deiodinase in the liver of the neonatal mouse

1988 ◽  
Vol 119 (2) ◽  
pp. 181-188 ◽  
Author(s):  
Doo Chol Han ◽  
Kanji Sato ◽  
Yuko Fujii ◽  
Minoru Ozawa ◽  
Hidehito Imamura ◽  
...  
Keyword(s):  
Single Injection ◽  
Inhibitory Effect ◽  
Antagonistic Effect ◽  
Time Dependent ◽  
Dependent Manner ◽  
Neonatal Mice ◽  
Dose Dependent Decrease ◽  
Dose Dependent

Abstract. To elucidate the effect of rT3 on iodothyronine-5′-deiodinating activity (I-5′-DA) in the liver of neonatal mice, rT3 was injected sc on the 5–8th day after birth and I-5′-DA in the liver was determined. A single injection of rT3 (0.01–1 μg/g) inhibited the ontogenetically developing I-5′-DA in a dose- and time-dependent manner. The inhibitory effect was reversible and specific for I-5′-DA. Lineweaver-Burk analysis revealed that the time- and dose-dependent decrease in the enzyme activity was due to a decrease in Vmax with no alteration in Km values (5 × 10−8 mol/l). The maximal inhibitory effect was observed at a dose of 1 μg rT3/g, whereas the inhibitory effect was diminished at greater doses (4–10 μg/g), probably owing to a contamination with T4 of the rT3 preparation administered. Furthermore, consistent with our previous in vitro findings, rT3 inhibited the I-5′-DA induced by T3 in the liver of neonatal mice. These findings suggest that rT3 inhibited I-5′-DA in the liver of neonatal mice by decreasing the amount of enzyme available to the substrate and that rT3 also elicited an antagonistic effect against T3 in the induction of I-5′-DA in vivo.

Adenovirus-mediated siRNA targeting Mcl-1 gene increases radiosensitivity of pancreatic carcinoma cells in vitro and in vivo

Surgery ◽  
2010 ◽  
Vol 147 (4) ◽  
pp. 553-561 ◽  
Author(s):  
Xiang Guoan ◽  
Wang Hanning ◽  
Chen Kaiyun ◽  
Liu Hao
Keyword(s):  
Pancreatic Carcinoma ◽  
Carcinoma Cells

Human pancreatic carcinoma cells are sensitive to photodynamic therapy in vitro and in vivo

1999 ◽  
Vol 86 (7) ◽  
pp. 899-906 ◽  
Author(s):  
A. Hajri ◽  
S. Coffy ◽  
F. Vallat ◽  
S. Evrard ◽  
J. Marescaux ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Pancreatic Carcinoma ◽  
Carcinoma Cells

Transient silencing of galectin-3 expression promotes both in vitro and in vivo drug-induced apoptosis of human pancreatic carcinoma cells

2011 ◽  
Vol 28 (4) ◽  
pp. 367-376 ◽  
Author(s):  
Tsutomu Kobayashi ◽  
Tatsuo Shimura ◽  
Toshiki Yajima ◽  
Norio Kubo ◽  
Kenichiro Araki ◽  
...  
Keyword(s):  
Pancreatic Carcinoma ◽  
Carcinoma Cells ◽  
Drug Induced ◽  
Galectin 3 ◽  
Induced Apoptosis
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