Pharmacokinetics, pharmacodynamics and glucose counterregulation following subcutaneous injection of the monomeric insulin analogue [Lys(B28),Pro(B29)] in IDDM RID=""ID="" Abbreviations: HI, Human insulin; MI, monomeric insulin; NEFA, non-esterified fatty acid; HGO, hepatic glucose production rate; β -OH-butyrate, β -hydroxy-butyrate; IDDM, insulin-dependent diabetes mellitus; NIDDM, non-insulin-dependent diabetes mellitus.

E. Torlone; C. Fanelli; A. M. Rambotti; G. Kassi; F. Modarelli; A. Di Vincenzo; L. Epifano; M. Ciofetta; S. Pampanelli; P. Brunetti; G. B. Bolli

doi:10.1007/s001250050169

Pharmacokinetics, pharmacodynamics and glucose counterregulation following subcutaneous injection of the monomeric insulin analogue [Lys(B28),Pro(B29)] in IDDM RID=""ID="" Abbreviations: HI, Human insulin; MI, monomeric insulin; NEFA, non-esterified fatty acid; HGO, hepatic glucose production rate; β -OH-butyrate, β -hydroxy-butyrate; IDDM, insulin-dependent diabetes mellitus; NIDDM, non-insulin-dependent diabetes mellitus.

Diabetologia ◽

10.1007/s001250050169 ◽

1994 ◽

Vol 37 (7) ◽

pp. 713-720 ◽

Cited By ~ 2

Author(s):

E. Torlone ◽

C. Fanelli ◽

A. M. Rambotti ◽

G. Kassi ◽

F. Modarelli ◽

...

Keyword(s):

Diabetes Mellitus ◽

Insulin Analogue ◽

Hepatic Glucose Production ◽

Glucose Production ◽

Insulin Dependent Diabetes Mellitus ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Hepatic Glucose ◽

Insulin Dependent ◽

Monomeric Insulin

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Dietary supplementation with n−3 fatty acids increases gluconeogenesis from glycerol but not hepatic glucose production in patients with non-insulin-dependent diabetes mellitus

American Journal of Clinical Nutrition ◽

10.1093/ajcn/61.1.121 ◽

1995 ◽

Vol 61 (1) ◽

pp. 121-126 ◽

Cited By ~ 48

Author(s):

I Puhakainen ◽

I Ahola ◽

H Yki-Järvinen

Keyword(s):

Diabetes Mellitus ◽

Fatty Acids ◽

Hepatic Glucose Production ◽

Dietary Supplementation ◽

Glucose Production ◽

Insulin Dependent Diabetes Mellitus ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Hepatic Glucose ◽

Insulin Dependent

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Inhibition by etomoxir of carnitine palmitoyltransferase I reduces hepatic glucose production and plasma lipids in non-insulin-dependent diabetes mellitus

Metabolism ◽

10.1016/0026-0495(91)90214-h ◽

1991 ◽

Vol 40 (11) ◽

pp. 1185-1190 ◽

Cited By ~ 50

Author(s):

K. Ratheiser ◽

B. Schneeweiß ◽

W. Waldhäusl ◽

P. Fasching ◽

A. Korn ◽

...

Keyword(s):

Diabetes Mellitus ◽

Plasma Lipids ◽

Hepatic Glucose Production ◽

Glucose Production ◽

Insulin Dependent Diabetes Mellitus ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Hepatic Glucose ◽

Insulin Dependent ◽

Carnitine Palmitoyltransferase I

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Incomplete suppression of hepatic glucose production in non-insulin dependent diabetes mellitus measured with [6,6-2H2]glucose enriched glucose infusion during hyperinsulinaemic euglycaemic clamps

European Journal of Clinical Investigation ◽

10.1111/j.1365-2362.1992.tb01458.x ◽

1992 ◽

Vol 22 (4) ◽

pp. 244-253 ◽

Cited By ~ 23

Author(s):

J. K. POWRIE ◽

G. D. SMITH ◽

T. R. HENNESSY ◽

F. SHOJAEE-MORADIE ◽

J. M. KELLY ◽

...

Keyword(s):

Diabetes Mellitus ◽

Hepatic Glucose Production ◽

Glucose Production ◽

Insulin Dependent Diabetes Mellitus ◽

Glucose Infusion ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Hepatic Glucose ◽

Insulin Dependent

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Quantification of the relative impairment in actions of insulin on hepatic glucose production and peripheral glucose uptake in non-insulin-dependent diabetes mellitus

Metabolism ◽

10.1016/0026-0495(88)90023-6 ◽

1988 ◽

Vol 37 (1) ◽

pp. 15-21 ◽

Cited By ~ 155

Author(s):

Peter J. Campbell ◽

Lawrence J. Mandarino ◽

John E. Gerich

Keyword(s):

Diabetes Mellitus ◽

Glucose Uptake ◽

Hepatic Glucose Production ◽

Glucose Production ◽

Insulin Dependent Diabetes Mellitus ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Hepatic Glucose ◽

Insulin Dependent

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Fasting hyperglycemia in non-insulin-dependent diabetes mellitus: Contributions of excessive hepatic glucose production and impaired tissue glucose uptake

Metabolism ◽

10.1016/0026-0495(89)90129-7 ◽

1989 ◽

Vol 38 (4) ◽

pp. 387-395 ◽

Cited By ~ 350

Author(s):

Ralph A. DeFronzo ◽

Eleuterio Ferrannini ◽

Donald C. Simonson

Keyword(s):

Diabetes Mellitus ◽

Glucose Uptake ◽

Hepatic Glucose Production ◽

Glucose Production ◽

Insulin Dependent Diabetes Mellitus ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Hepatic Glucose ◽

Insulin Dependent

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The biochemical basis of increased hepatic glucose production in a mouse model of type 2 (non-insulin-dependent) diabetes mellitus

Diabetologia ◽

10.1007/bf00400598 ◽

1995 ◽

Vol 38 (12) ◽

pp. 1389-1396 ◽

Cited By ~ 32

Author(s):

S. Andrikopoulos ◽

J. Proietto

Keyword(s):

Diabetes Mellitus ◽

Mouse Model ◽

Hepatic Glucose Production ◽

Glucose Production ◽

Insulin Dependent Diabetes Mellitus ◽

Dependent Diabetes Mellitus ◽

Biochemical Basis ◽

Hepatic Glucose ◽

Insulin Dependent

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Modulation of hepatic glucose production by non-esterified fatty acids in Type 2 (non-insulin-dependent) diabetes mellitus

Diabetologia ◽

10.1007/bf00403179 ◽

1991 ◽

Vol 34 (6) ◽

pp. 409-415 ◽

Cited By ~ 70

Author(s):

C. Saloranta ◽

A. Franssila-Kallunki ◽

A. Ekstrand ◽

M. -R. Taskinen ◽

L. Groop

Keyword(s):

Diabetes Mellitus ◽

Fatty Acids ◽

Hepatic Glucose Production ◽

Glucose Production ◽

Insulin Dependent Diabetes Mellitus ◽

Dependent Diabetes Mellitus ◽

Esterified Fatty Acids ◽

Hepatic Glucose ◽

Insulin Dependent

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Insulin secretion, insulin action, and hepatic glucose production in identical twins discordant for non-insulin-dependent diabetes mellitus.

Journal of Clinical Investigation ◽

10.1172/jci117715 ◽

1995 ◽

Vol 95 (2) ◽

pp. 690-698 ◽

Cited By ~ 117

Author(s):

A Vaag ◽

J E Henriksen ◽

S Madsbad ◽

N Holm ◽

H Beck-Nielsen

Keyword(s):

Diabetes Mellitus ◽

Insulin Secretion ◽

Insulin Action ◽

Hepatic Glucose Production ◽

Glucose Production ◽

Insulin Dependent Diabetes Mellitus ◽

Identical Twins ◽

Dependent Diabetes Mellitus ◽

Hepatic Glucose ◽

Insulin Dependent

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Normalization of hepatic glucose regulation despite systemic insulin delivery. Studies in patients with pancreatic transplantation for Type 1 (insulin-dependent) diabetes mellitus

Diabetologia ◽

10.1007/bf00405007 ◽

1991 ◽

Vol 34 (5) ◽

pp. 345-349 ◽

Cited By ~ 9

Author(s):

H. Wilczek ◽

R. Gunnarsson ◽

P. Felig ◽

J. �stman ◽

C. -G. Groth ◽

...

Keyword(s):

Diabetes Mellitus ◽

Insulin Delivery ◽

Insulin Dependent Diabetes Mellitus ◽

Insulin Dependent Diabetes ◽

Glucose Regulation ◽

Dependent Diabetes Mellitus ◽

Pancreatic Transplantation ◽

Hepatic Glucose ◽

Insulin Dependent

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On the determination of basal glucose production rate in patients with Type 2 (non-insulin-dependent) diabetes mellitus using primed-continuous 3-3H-glucose infusion

Diabetologia ◽

10.1007/bf00400204 ◽

1990 ◽

Vol 33 (10) ◽

pp. 603-610 ◽

Cited By ~ 100

Author(s):

O. Hother-Nielsen ◽

H. Beck-Nielsen

Keyword(s):

Diabetes Mellitus ◽

Production Rate ◽

Glucose Production ◽

Insulin Dependent Diabetes Mellitus ◽

Glucose Infusion ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Insulin Dependent

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