scholarly journals Hierarchical correction of p-values via an ultrametric tree running Ornstein-Uhlenbeck process

Author(s):  
Antoine Bichat ◽  
Christophe Ambroise ◽  
Mahendra Mariadassou

AbstractStatistical testing is classically used as an exploratory tool to search for association between a phenotype and many possible explanatory variables. This approach often leads to multiple testing under dependence. We assume a hierarchical structure between tests via an Ornstein-Uhlenbeck process on a tree. The process correlation structure is used for smoothing the p-values. We design a penalized estimation of the mean of the Ornstein-Uhlenbeck process for p-value computation. The performances of the algorithm are assessed via simulations. Its ability to discover new associations is demonstrated on a metagenomic dataset. The corresponding R package is available from https://github.com/abichat/zazou.

1975 ◽  
Vol 12 (3) ◽  
pp. 600-604 ◽  
Author(s):  
Marlin U. Thomas

This paper describes an accurate method of approximating the mean of the first-passage time distribution for an Ornstein-Uhlenbeck process with a single absorbing barrier. The accuracy of the approximation is demonstrated through some numerical comparisons.


Author(s):  
Baodan Tian ◽  
Liu Yang ◽  
Xingzhi Chen ◽  
Yong Zhang

A generalized competitive system with stochastic perturbations is proposed in this paper, in which the stochastic disturbances are described by the famous Ornstein–Uhlenbeck process. By theories of stochastic differential equations, such as comparison theorem, Itô’s integration formula, Chebyshev’s inequality, martingale’s properties, etc., the existence and the uniqueness of global positive solution of the system are obtained. Then sufficient conditions for the extinction of the species almost surely, persistence in the mean and the stochastic permanence for the system are derived, respectively. Finally, by a series of numerical examples, the feasibility and correctness of the theoretical analysis results are verified intuitively. Moreover, the effects of the intensity of the stochastic perturbations and the speed of the reverse in the Ornstein–Uhlenbeck process to the dynamical behavior of the system are also discussed.


1975 ◽  
Vol 12 (03) ◽  
pp. 600-604 ◽  
Author(s):  
Marlin U. Thomas

This paper describes an accurate method of approximating the mean of the first-passage time distribution for an Ornstein-Uhlenbeck process with a single absorbing barrier. The accuracy of the approximation is demonstrated through some numerical comparisons.


2020 ◽  
Vol 31 (12) ◽  
pp. 2050176
Author(s):  
J. L. S. Soares ◽  
R. D. dos Santos ◽  
F. J. S. Sousa ◽  
M. O. Sales ◽  
F. A. B. F. Moura

In this paper, we present a detailed study of the electronic dynamics in systems with correlated disorder generated from the Ornstein–Uhlenbeck process (OU). In short, we used numeric methods for solving the time-dependent Schrödinger equation. We apply a Taylor’s expansion of the evolution operator in order to solve the differential equation. We calculate some typical tools, such as the participation function [Formula: see text], the mean square displacement [Formula: see text] and the probability of return [Formula: see text]. In our analysis, we show that for low correlations the system behaves as in the standard Anderson model (i.e. all eigenstates are localized). For strong correlations, our results suggest the existence of a quasi-ballistic dynamics.


2020 ◽  
Vol 23 (2) ◽  
pp. 450-483 ◽  
Author(s):  
Giacomo Ascione ◽  
Yuliya Mishura ◽  
Enrica Pirozzi

AbstractWe define a time-changed fractional Ornstein-Uhlenbeck process by composing a fractional Ornstein-Uhlenbeck process with the inverse of a subordinator. Properties of the moments of such process are investigated and the existence of the density is shown. We also provide a generalized Fokker-Planck equation for the density of the process.


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