In this paper, we discuss the conditions under which blow-up occurs for the
solutions of reaction-diffusion equations on networks. The analysis of this
class of problems includes the existence of blow-up in finite time and the
determination of the blow-up time and the corresponding blow-up rate. In
addition, when the solution blows up, we give estimates for the blow-up time
and also provide the blow-up rate. Finally, we show some numerical
illustrations which describe the main results.