Histamine H1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers

Hirotoshi Sato; Chihiro Ito; Kotaro Hiraoka; Manabu Tashiro; Katsuhiko Shibuya; Yoshihito Funaki; Takeo Yoshikawa; Ren Iwata; Hiroo Matsuoka; Kazuhiko Yanai

doi:10.1007/s00213-015-4002-2

Histamine H1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers

Psychopharmacology ◽

10.1007/s00213-015-4002-2 ◽

2015 ◽

Vol 232 (19) ◽

pp. 3497-3505 ◽

Cited By ~ 13

Author(s):

Hirotoshi Sato ◽

Chihiro Ito ◽

Kotaro Hiraoka ◽

Manabu Tashiro ◽

Katsuhiko Shibuya ◽

...

Keyword(s):

Positron Emission Tomography ◽

Healthy Volunteers ◽

Receptor Occupancy ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

H1 Receptor ◽

Histamine H1 Receptor ◽

Positron Emission ◽

New Generation ◽

Histamine H1 Receptor Occupancy

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Histamine H1 receptor occupancy by the new-generation antidepressants fluvoxamine and mirtazapine: a positron emission tomography study in healthy volunteers

Psychopharmacology ◽

10.1007/s00213-013-3146-1 ◽

2013 ◽

Vol 230 (2) ◽

pp. 227-234 ◽

Cited By ~ 12

Author(s):

Hirotoshi Sato ◽

Chihiro Ito ◽

Manabu Tashiro ◽

Kotaro Hiraoka ◽

Katsuhiko Shibuya ◽

...

Keyword(s):

Positron Emission Tomography ◽

Healthy Volunteers ◽

Receptor Occupancy ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

H1 Receptor ◽

Histamine H1 Receptor ◽

Positron Emission ◽

New Generation ◽

Histamine H1 Receptor Occupancy

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Histamine H1 Receptor Occupancy in the Human Brain Measured by Positron Emission Tomography

Histamine Receptors ◽

10.1007/978-3-319-40308-3_13 ◽

2016 ◽

pp. 311-325

Author(s):

Kazuhiko Yanai ◽

Kotaro Hiraoka ◽

Anikó Kárpáti ◽

Fumito Naganuma ◽

Nobuyuki Okamura ◽

...

Keyword(s):

Positron Emission Tomography ◽

Human Brain ◽

Receptor Occupancy ◽

Emission Tomography ◽

H1 Receptor ◽

Histamine H1 Receptor ◽

Positron Emission ◽

Histamine H1 Receptor Occupancy

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Neuroimaging of histamine H1 -receptor occupancy in human brain by positron emission tomography (PET): A comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine

British Journal of Clinical Pharmacology ◽

10.1046/j.1365-2125.2001.01471.x ◽

2001 ◽

Vol 52 (5) ◽

pp. 501-509 ◽

Cited By ~ 66

Author(s):

Masaaki Tagawa ◽

Michiko Kano ◽

Nobuyuki Okamura ◽

Makoto Higuchi ◽

Michiaki Matsuda ◽

...

Keyword(s):

Positron Emission Tomography ◽

Comparative Study ◽

Human Brain ◽

Second Generation ◽

Receptor Occupancy ◽

Emission Tomography ◽

H1 Receptor ◽

Histamine H1 Receptor ◽

Positron Emission ◽

Histamine H1 Receptor Occupancy

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Brain histamine H1 receptor occupancy of orally administered antihistamines measured by positron emission tomography with 11C-doxepin in a placebo-controlled crossover study design in healthy subjects: a comparison of olopatadine and ketotifen

British Journal of Clinical Pharmacology ◽

10.1111/j.1365-2125.2005.02514.x ◽

2006 ◽

Vol 61 (1) ◽

pp. 16-26 ◽

Cited By ~ 49

Author(s):

Manabu Tashiro ◽

Hideki Mochizuki ◽

Yumiko Sakurada ◽

Kenji Ishii ◽

Keiichi Oda ◽

...

Keyword(s):

Positron Emission Tomography ◽

Crossover Study ◽

Study Design ◽

Healthy Subjects ◽

Receptor Occupancy ◽

Emission Tomography ◽

H1 Receptor ◽

Brain Histamine ◽

Positron Emission ◽

Histamine H1 Receptor Occupancy

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Central Effects of Fexofenadine and Cetirizine: Measurement of Psychomotor Performance, Subjective Sleepiness, and Brain Histamine H1-Receptor Occupancy Using11C-Doxepin Positron Emission Tomography

The Journal of Clinical Pharmacology ◽

10.1177/0091270004267590 ◽

2004 ◽

Vol 44 (8) ◽

pp. 890-900 ◽

Cited By ~ 89

Author(s):

Manabu Tashiro ◽

Yumiko Sakurada ◽

Kentaro Iwabuchi ◽

Hideki Mochizuki ◽

Motohisa Kato ◽

...

Keyword(s):

Positron Emission Tomography ◽

Psychomotor Performance ◽

Receptor Occupancy ◽

Emission Tomography ◽

H1 Receptor ◽

Brain Histamine ◽

Central Effects ◽

Positron Emission ◽

Subjective Sleepiness ◽

Histamine H1 Receptor Occupancy

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Histamine H1 receptor occupancy in human brains after single oral doses of histamine H1 antagonists measured by positron emission tomography

British Journal of Pharmacology ◽

10.1111/j.1476-5381.1995.tb16386.x ◽

1995 ◽

Vol 116 (1) ◽

pp. 1649-1655 ◽

Cited By ~ 78

Author(s):

Kazuhiko Yanai ◽

Jong Hoon Ryu ◽

Takehiko Watanabe ◽

Ren Iwata ◽

Tatsuo Ido ◽

...

Keyword(s):

Positron Emission Tomography ◽

Receptor Occupancy ◽

Emission Tomography ◽

H1 Receptor ◽

Positron Emission ◽

Human Brains ◽

Oral Doses ◽

H1 Antagonists ◽

Histamine H1 Antagonists ◽

Histamine H1 Receptor Occupancy

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A positron emission tomography study in healthy volunteers to estimate mGluR5 receptor occupancy of AZD2066 — Estimating occupancy in the absence of a reference region

NeuroImage ◽

10.1016/j.neuroimage.2013.05.006 ◽

2013 ◽

Vol 82 ◽

pp. 160-169 ◽

Cited By ~ 30

Author(s):

Matts Kågedal ◽

Zsolt Cselényi ◽

Svante Nyberg ◽

Patrick Raboisson ◽

Lars Ståhle ◽

...

Keyword(s):

Positron Emission Tomography ◽

Healthy Volunteers ◽

Receptor Occupancy ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

Reference Region ◽

Positron Emission

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Faculty Opinions recommendation of Decreased [18F]MPPF binding potential in the dorsal raphe nucleus after a single oral dose of fluoxetine: a positron-emission tomography study in healthy volunteers.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1115675.571742 ◽

2008 ◽

Author(s):

Ahmad Hariri ◽

Patrick Fisher

Keyword(s):

Positron Emission Tomography ◽

Oral Dose ◽

Healthy Volunteers ◽

Single Oral Dose ◽

Dorsal Raphe Nucleus ◽

Raphe Nucleus ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

Binding Potential ◽

Positron Emission

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Correction to: An open-label, positron emission tomography study of the striatal D2/D3 receptor occupancy and pharmacokinetics of single-dose oral brexpiprazole in healthy participants

European Journal of Clinical Pharmacology ◽

10.1007/s00228-020-03071-z ◽

2021 ◽

Author(s):

Dean F. Wong ◽

Arash Raoufinia ◽

Patricia Bricmont ◽

James R. Brašić ◽

Robert D. McQuade ◽

...

Keyword(s):

Positron Emission Tomography ◽

Single Dose ◽

Receptor Occupancy ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

D3 Receptor ◽

Open Label ◽

Positron Emission ◽

Dose Oral ◽

Healthy Participants

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5-Hydroxytryptamine1A Receptor Occupancy by Novel Full Antagonist 2-[4-[4-(7-Chloro-2,3-dihydro-1,4-benzdioxyn-5-yl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3-(2H)-one-1,1-dioxide: A [11C][O-methyl-3H]-N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide Trihydrochloride (WAY-100635) Positron Emission Tomography Study in Humans

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.301.3.1144 ◽

2002 ◽

Vol 301 (3) ◽

pp. 1144-1150 ◽

Cited By ~ 37

Author(s):

Eugenii A. Rabiner ◽

Martin R. Wilkins ◽

Federico Turkheimer ◽

Roger N. Gunn ◽

Joanna Udo de Haes ◽

...

Keyword(s):

Positron Emission Tomography ◽

Receptor Occupancy ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

Positron Emission ◽

Way 100635

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