Brain histamine H1 receptor occupancy of orally administered antihistamines measured by positron emission tomography with 11C-doxepin in a placebo-controlled crossover study design in healthy subjects: a comparison of olopatadine and ketotifen

Crossover Study ◽

Study Design ◽

Healthy Subjects ◽

Receptor Occupancy ◽

Emission Tomography ◽

H1 Receptor ◽

Brain Histamine ◽

Positron Emission ◽

Central Effects of Fexofenadine and Cetirizine: Measurement of Psychomotor Performance, Subjective Sleepiness, and Brain Histamine H1-Receptor Occupancy Using11C-Doxepin Positron Emission Tomography

The Journal of Clinical Pharmacology ◽

10.1177/0091270004267590 ◽

2004 ◽

Vol 44 (8) ◽

pp. 890-900 ◽

Cited By ~ 89

Author(s):

Manabu Tashiro ◽

Yumiko Sakurada ◽

Kentaro Iwabuchi ◽

Hideki Mochizuki ◽

Motohisa Kato ◽

...

Keyword(s):

Psychomotor Performance ◽

Receptor Occupancy ◽

Emission Tomography ◽

H1 Receptor ◽

Brain Histamine ◽

Central Effects ◽

Positron Emission ◽

Subjective Sleepiness ◽

Histamine H1 Receptor Occupancy in the Human Brain Measured by Positron Emission Tomography

Histamine Receptors ◽

10.1007/978-3-319-40308-3_13 ◽

2016 ◽

pp. 311-325

Author(s):

Kazuhiko Yanai ◽

Kotaro Hiraoka ◽

Anikó Kárpáti ◽

Fumito Naganuma ◽

Nobuyuki Okamura ◽

...

Keyword(s):

Human Brain ◽

Receptor Occupancy ◽

Emission Tomography ◽

H1 Receptor ◽

Histamine H1 Receptor ◽

Positron Emission ◽

Histamine H1 receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers

Psychopharmacology ◽

10.1007/s00213-015-4002-2 ◽

2015 ◽

Vol 232 (19) ◽

pp. 3497-3505 ◽

Cited By ~ 13

Author(s):

Hirotoshi Sato ◽

Chihiro Ito ◽

Kotaro Hiraoka ◽

Manabu Tashiro ◽

Katsuhiko Shibuya ◽

...

Keyword(s):

Healthy Volunteers ◽

Receptor Occupancy ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

H1 Receptor ◽

Histamine H1 Receptor ◽

Positron Emission ◽

New Generation ◽

Neuroimaging of histamine H1 -receptor occupancy in human brain by positron emission tomography (PET): A comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine

British Journal of Clinical Pharmacology ◽

10.1046/j.1365-2125.2001.01471.x ◽

2001 ◽

Vol 52 (5) ◽

pp. 501-509 ◽

Cited By ~ 66

Author(s):

Masaaki Tagawa ◽

Michiko Kano ◽

Nobuyuki Okamura ◽

Makoto Higuchi ◽

Michiaki Matsuda ◽

...

Keyword(s):

Comparative Study ◽

Human Brain ◽

Second Generation ◽

Receptor Occupancy ◽

Emission Tomography ◽

H1 Receptor ◽

Histamine H1 Receptor ◽

Positron Emission ◽

Histamine H1 receptor occupancy in human brains after single oral doses of histamine H1 antagonists measured by positron emission tomography

British Journal of Pharmacology ◽

10.1111/j.1476-5381.1995.tb16386.x ◽

1995 ◽

Vol 116 (1) ◽

pp. 1649-1655 ◽

Cited By ~ 78

Author(s):

Kazuhiko Yanai ◽

Jong Hoon Ryu ◽

Takehiko Watanabe ◽

Ren Iwata ◽

Tatsuo Ido ◽

...

Keyword(s):

Receptor Occupancy ◽

Emission Tomography ◽

H1 Receptor ◽

Positron Emission ◽

Human Brains ◽

Oral Doses ◽

H1 Antagonists ◽

Histamine H1 Antagonists ◽

Histamine H1 receptor occupancy by the new-generation antidepressants fluvoxamine and mirtazapine: a positron emission tomography study in healthy volunteers

Psychopharmacology ◽

10.1007/s00213-013-3146-1 ◽

2013 ◽

Vol 230 (2) ◽

pp. 227-234 ◽

Cited By ~ 12

Author(s):

Hirotoshi Sato ◽

Chihiro Ito ◽

Manabu Tashiro ◽

Kotaro Hiraoka ◽

Katsuhiko Shibuya ◽

...

Keyword(s):

Healthy Volunteers ◽

Receptor Occupancy ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

H1 Receptor ◽

Histamine H1 Receptor ◽

Positron Emission ◽

New Generation ◽

Faculty Opinions recommendation of D₂-receptor occupancy measurement of JNJ-37822681, a novel fast off-rate D₂-receptor antagonist, in healthy subjects using positron emission tomography: single dose versus steady state and dose selection.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717953114.793458670 ◽

2012 ◽

Author(s):

John Davis

Keyword(s):

Single Dose ◽

Steady State ◽

Receptor Antagonist ◽

Healthy Subjects ◽

Receptor Occupancy ◽

Emission Tomography ◽

Dose Selection ◽

Dopamine D2 receptor occupancy by perospirone: a positron emission tomography study in patients with schizophrenia and healthy subjects

Psychopharmacology ◽

10.1007/s00213-010-1783-1 ◽

2010 ◽

Vol 209 (4) ◽

pp. 285-290 ◽

Cited By ~ 7

Author(s):

Ryosuke Arakawa ◽

Hiroshi Ito ◽

Akihiro Takano ◽

Masaki Okumura ◽

Hidehiko Takahashi ◽

...

Keyword(s):

Healthy Subjects ◽

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Occupancy ◽

Emission Tomography ◽

Positron Emission Tomography Study ◽

Dopamine D2 ◽

Dopamine D2 Receptor Occupancy ◽

Faculty Opinions recommendation of D₂-receptor occupancy measurement of JNJ-37822681, a novel fast off-rate D₂-receptor antagonist, in healthy subjects using positron emission tomography: single dose versus steady state and dose selection.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717953114.793459582 ◽

2012 ◽

Author(s):

Christoph U Correll

Keyword(s):

Single Dose ◽

Steady State ◽

Receptor Antagonist ◽

Healthy Subjects ◽

Receptor Occupancy ◽

Emission Tomography ◽

Dose Selection ◽

D2-receptor occupancy measurement of JNJ-37822681, a novel fast off-rate D2-receptor antagonist, in healthy subjects using positron emission tomography: single dose versus steady state and dose selection

Psychopharmacology ◽

10.1007/s00213-012-2782-1 ◽

2012 ◽

Vol 224 (4) ◽

pp. 549-557 ◽

Cited By ~ 3

Author(s):

Mark E. Schmidt ◽

Peter de Boer ◽

Randolph Andrews ◽

Martine Neyens ◽

Stefaan Rossenu ◽

...

Keyword(s):

Single Dose ◽

Steady State ◽

Receptor Antagonist ◽

Healthy Subjects ◽

D2 Receptor ◽

Receptor Occupancy ◽

Emission Tomography ◽

Dose Selection ◽