Effects of repeated treatment with the 5-HT1A and 5-HT1B agonists (R)-( +)-8-hydroxy-DPAT and CP-94253 on the locomotor activity and axillary temperatures of preweanling rats: evidence of tolerance and behavioral sensitization

2021 ◽  
Author(s):  
Sanders A. McDougall ◽  
Jordan A. Taylor ◽  
Matthew J. Roe ◽  
Constance J. Greenwood
Keyword(s):  
Locomotor Activity ◽  
Behavioral Sensitization ◽  
Repeated Treatment

Alterations In Glutamate Synapses In The Nucleus Accumbens Following Sensitization To Cocaine

1999 ◽  
Vol 5 (S2) ◽  
pp. 1232-1233
Author(s):  
L. B. Kozell ◽  
C. K. Meshul
Keyword(s):  
Prefrontal Cortex ◽  
Locomotor Activity ◽  
Nucleus Accumbens ◽  
Behavioral Sensitization ◽  
Neural Mechanism ◽  
Cocaine Administration ◽  
Collaborative Studies ◽  
Abundant Evidence ◽  
Dopaminergic Pathways ◽  
Intermittent Cocaine

Repeated intermittent administration of cocaine to rodents has been shown to result in behavioral sensitization, or enhanced locomotor activity. Because there are similarities between effects of intermittent cocaine use in humans and sensitization in rats, understanding the neural mechanism underlying sensitization may provide insights into mechanisms of psychopathologies in humans.There is abundant evidence that the mesolimbic dopaminergic pathways, originating in the ventral tegmental area (VTA) and terminating in both nucleus accumbens (NAc) and prefrontal cortex (PFC), are critically important for development of sensitization to the motor-stimulating effects of cocaine. Evidence also suggests that changes in glutamate (Glu) transmission in the mesolimbic DA pathways are associated with sensitization to cocaine. In recent collaborative studies, we have shown that cocaine administration transiently decreases the density of nerve terminal glutamate immunolabeling within the NAc shell following withdrawal from continuous or intermittent cocaine administration. Locomotor activity was not assessed in either of these studies.

P.6.f.003 Rimonabant repeated treatment inhibits behavioral sensitization previously developed to morphine in mice

2009 ◽  
Vol 19 ◽  
pp. S676-S677
Author(s):  
E.A.V. Marinho ◽  
R. Santos ◽  
A.J. Oliveira-Lima ◽  
F.W. Silva ◽  
M.A. Baldaia ◽  
...  
Keyword(s):  
Behavioral Sensitization ◽  
Repeated Treatment

Effects of repeated treatment with methamphetamine plus scopolamine and methamphetamine on behavioral sensitization and conditioning

1996 ◽  
Vol 80 (1-2) ◽  
pp. 169-175 ◽  
Author(s):  
Kunio Yui ◽  
Takao Miura ◽  
Kimihito Sugiyama ◽  
Mamoru Ono ◽  
Moriharu Nagase
Keyword(s):  
Behavioral Sensitization ◽  
Repeated Treatment

Locomotor activity changes in female adolescent and adult rats during repeated treatment with a cannabinoid or club drug

2011 ◽  
Vol 63 (5) ◽  
pp. 1085-1092 ◽  
Author(s):  
Jenny L. Wiley ◽  
Rhys L. Evans ◽  
Darren B. Grainger ◽  
Katherine L. Nicholson
Keyword(s):  
Locomotor Activity ◽  
Female Adolescent ◽  
Repeated Treatment ◽  
Adult Rats ◽  
Club Drug

scholarly journals Effects of Fentanyl on Acute Locomotor Activity, Behavioral Sensitization, and Contextual Reward in Female and Male Rats

2021 ◽  
pp. 109101
Author(s):  
Andrew D. Gaulden ◽  
Nicole Burson ◽  
Nareen Sadik ◽  
Ishita Ghosh ◽  
Sabrina Khan ◽  
...  
Keyword(s):  
Locomotor Activity ◽  
Behavioral Sensitization ◽  
Male Rats

scholarly journals μ-Opioid Receptors are not Involved in Acute Cocaine-Induced Locomotor Activity nor in Development of Cocaine-Induced Behavioral Sensitization in Mice

2004 ◽  
Vol 30 (2) ◽  
pp. 278-285 ◽  
Author(s):  
Heidi M B Lesscher ◽  
Michiel Hordijk ◽  
Natalia P Bondar ◽  
Olga V Alekseyenko ◽  
J Peter H Burbach ◽  
...  
Keyword(s):  
Locomotor Activity ◽  
Opioid Receptors ◽  
Behavioral Sensitization ◽  
Μ Opioid Receptors

Effect of repeated treatment with lamotrigine on locomotor activity and on DOI-elicited wet dog shakes in rats

2002 ◽  
Vol 17 (3) ◽  
pp. 149-159
Author(s):  
Katagiri ◽  
Kozuru ◽  
Kagaya ◽  
Kawano ◽  
Yamawaki ◽  
...  
Keyword(s):  
Locomotor Activity ◽  
Repeated Treatment ◽  
Wet Dog Shakes
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