Starch–lipid complex formation during extrusion-cooking of model system (rice starch and oleic acid) and real food (rice starch and pistachio nut flour)

2012 ◽  
Vol 234 (3) ◽  
pp. 517-525 ◽  
Author(s):  
T. De Pilli ◽  
A. Derossi ◽  
R. A. Talja ◽  
K. Jouppila ◽  
C. Severini
2013 ◽  
Vol 49 (2) ◽  
pp. 309-316 ◽  
Author(s):  
Madonna T. Thachil ◽  
Mithlesh K. Chouksey ◽  
Venkateshwarlu Gudipati

1997 ◽  
Vol 74 (2) ◽  
pp. 159-162 ◽  
Author(s):  
Hua Liu ◽  
Susan D. Arntfield ◽  
Richard A. Holley ◽  
David B. Aime

2015 ◽  
Vol 63 (16) ◽  
pp. 4202-4210 ◽  
Author(s):  
Emily Oluwaseun Arijaje ◽  
Ya-Jane Wang

Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4336
Author(s):  
Katherine E. Chetta ◽  
Joseph L. Alcorn ◽  
John E. Baatz ◽  
Carol L. Wagner

Frozen storage is necessary to preserve expressed human milk for critically ill and very preterm infants. Milk pasteurization is essential for donor milk given to this special population. Due to these storage and processing conditions, subtle changes occur in milk nutrients. These changes may have clinical implications. Potentially, bioactive complexes of unknown significance could be found in human milk given to preterm infants. One such complex, a cytotoxic α-lactalbumin-oleic acid complex named “HAMLET,” (Human Alpha-Lactalbumin Made Lethal to Tumor cells) is a folding variant of alpha-lactalbumin that is bound to oleic acid. This complex, isolated from human milk casein, has specific toxicity to both carcinogenic cell lines and immature non-transformed cells. Both HAMLET and free oleic acid trigger similar apoptotic mechanisms in tissue and stimulate inflammation via the NF-κB and MAPK p38 signaling pathways. This protein-lipid complex could potentially trigger various inflammatory pathways with unknown consequences, especially in immature intestinal tissues. The very preterm population is dependent on human milk as a medicinal and broadly bioactive nutriment. Therefore, HAMLET’s possible presence and bioactive role in milk should be addressed in neonatal research. Through a pediatric lens, HAMLET’s discovery, formation and bioactive benefits will be reviewed.


Biochemistry ◽  
1996 ◽  
Vol 35 (17) ◽  
pp. 5495-5508 ◽  
Author(s):  
Tina L. Trapane ◽  
Richard I. Hogrefe ◽  
Mark A. Reynolds ◽  
Lou-sing Kan ◽  
Paul O. P. Ts'o

2000 ◽  
Vol 71 (4) ◽  
pp. 511-517 ◽  
Author(s):  
Kulwinder Kaur ◽  
Narpinder Singh

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