Glial cell proliferation in the spinal cord after dorsal rhizotomy or sciatic nerve transection in the adult rat

2000 ◽  
Vol 131 (1) ◽  
pp. 64-73 ◽  
Author(s):  
L. Liu ◽  
M. Rudin ◽  
E.N. Kozlova
Keyword(s):  
Spinal Cord ◽  
Cell Proliferation ◽  
Sciatic Nerve ◽  
Glial Cell ◽  
Nerve Transection ◽  
Sciatic Nerve Transection ◽  
Dorsal Rhizotomy ◽  
Adult Rat ◽  
Glial Cell Proliferation

Neonatal sciatic nerve transection induces TUNEL labeling of neurons in the rat spinal cord and DRG

Neuroreport ◽  
1997 ◽  
Vol 8 (13) ◽  
pp. 2837-2840 ◽  
Author(s):  
A L. R. Oliveira ◽  
M Risling ◽  
M Deckner ◽  
T Lindholm ◽  
F Langone ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Sciatic Nerve ◽  
Nerve Transection ◽  
Rat Spinal Cord ◽  
Sciatic Nerve Transection

Glial cell line-derived neurotrophic factor enhances axonal regeneration following sciatic nerve transection in adult rats

2001 ◽  
Vol 902 (2) ◽  
pp. 272-276 ◽  
Author(s):  
Zhe-Yu Chen ◽  
Yan-Feng Chai ◽  
Li Cao ◽  
Chang-Lin Lu ◽  
Cheng He
Keyword(s):  
Sciatic Nerve ◽  
Cell Line ◽  
Glial Cell ◽  
Neurotrophic Factor ◽  
Axonal Regeneration ◽  
Nerve Transection ◽  
Adult Rats ◽  
Sciatic Nerve Transection

scholarly journals Effect of Sciatic Nerve Transection on acetylcholinesterase activity in spinal cord and skeletal muscles of the bullfrog Lithobates catesbeianus

2017 ◽  
Vol 78 (2) ◽  
pp. 217-223
Author(s):  
A. Kroth ◽  
V. Mackedanz ◽  
C. Matté ◽  
A. T. S. Wyse ◽  
M. F. M. Ribeiro ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Neuropathic Pain ◽  
Sciatic Nerve ◽  
Skeletal Muscles ◽  
Ache Activity ◽  
Clinical Symptoms ◽  
Phantom Limb ◽  
Nerve Transection ◽  
Sciatic Nerve Transection ◽  
Lithobates Catesbeianus

Abstract Sciatic nerve transection (SNT), a model for studying neuropathic pain, mimics the clinical symptoms of “phantom limb”, a pain condition that arises in humans after amputation or transverse spinal lesions. In some vertebrate tissues, this condition decreases acetylcholinesterase (AChE) activity, the enzyme responsible for fast hydrolysis of released acetylcholine in cholinergic synapses. In spinal cord of frog Rana pipiens, this enzyme’s activity was not significantly changed in the first days following ventral root transection, another model for studying neuropathic pain. An answerable question is whether SNT decreases AChE activity in spinal cord of frog Lithobates catesbeianus, a species that has been used as a model for studying SNT-induced neuropathic pain. Since each animal model has been created with a specific methodology, and the findings tend to vary widely with slight changes in the method used to induce pain, our study assessed AChE activity 3 and 10 days after complete SNT in lumbosacral spinal cord of adult male bullfrog Lithobates catesbeianus. Because there are time scale differences of motor endplate maturation in rat skeletal muscles, our study also measured the AChE activity in bullfrog tibial posticus (a postural muscle) and gastrocnemius (a typical skeletal muscle that is frequently used to study the motor system) muscles. AChE activity did not show significant changes 3 and 10 days following SNT in spinal cord. Also, no significant change occurred in AChE activity in tibial posticus and gastrocnemius muscles at day 3. However, a significant decrease was found at day 10, with reductions of 18% and 20% in tibial posticus and gastrocnemius, respectively. At present we cannot explain this change in AChE activity. While temporally different, the direction of the change was similar to that described for rats. This similarity indicates that bullfrog is a valid model for investigating AChE activity following SNT.

mRNA and protein expression and activities of nitric oxide synthases in the lumbar spinal cord of neonatal rats after sciatic nerve transection and melatonin administration

2006 ◽  
Vol 407 (2) ◽  
pp. 182-187 ◽  
Author(s):  
Fábio Rogério ◽  
Simone Aparecida Teixeira ◽  
Hamilton Jordão Júnior ◽  
Carla Cristina Judice Maria ◽  
André Schwambach Vieira ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Spinal Cord ◽  
Sciatic Nerve ◽  
Lumbar Spinal Cord ◽  
Nerve Transection ◽  
Neonatal Rats ◽  
Sciatic Nerve Transection ◽  
Melatonin Administration ◽  
Mrna And Protein Expression ◽  
Lumbar Spinal

Thyroid hormone reduces the loss of axotomized sensory neurons in dorsal root ganglia after sciatic nerve transection in adult rat

2003 ◽  
Vol 184 (1) ◽  
pp. 225-236 ◽  
Author(s):  
Michel Schenker ◽  
Rudolf Kraftsik ◽  
Liliane Glauser ◽  
Thierry Kuntzer ◽  
Julien Bogousslavsky ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Sciatic Nerve ◽  
Sensory Neurons ◽  
Dorsal Root Ganglia ◽  
Dorsal Root ◽  
Nerve Transection ◽  
Sciatic Nerve Transection ◽  
Adult Rat

Release of immunoreactive brain-derived neurotrophic factor in the spinal cord of the rat following sciatic nerve transection.

2001 ◽  
Vol 899 (1-2) ◽  
pp. 240-247 ◽  
Author(s):  
Suellen M Walker ◽  
Vanessa A Mitchell ◽  
Deborah M White ◽  
Robert A Rush ◽  
Arthur W Duggan
Keyword(s):  
Spinal Cord ◽  
Sciatic Nerve ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Nerve Transection ◽  
Sciatic Nerve Transection

Effect of Treadmill Exercise on Serotonin Immunoreactivity in Medullary Raphe Nuclei and Spinal Cord Following Sciatic Nerve Transection in Rats

2009 ◽  
Vol 35 (3) ◽  
pp. 380-389 ◽  
Author(s):  
Arthiese Korb ◽  
Leandro Viçosa Bonetti ◽  
Sandro Antunes da Silva ◽  
Simone Marcuzzo ◽  
Jocemar Ilha ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Sciatic Nerve ◽  
Treadmill Exercise ◽  
Raphe Nuclei ◽  
Nerve Transection ◽  
Sciatic Nerve Transection ◽  
Medullary Raphe ◽  
Serotonin Immunoreactivity ◽  
Raphé Nuclei
Sign in / Sign up

Export Citation Format

Share Document