Z-Score Reference Ranges for Fetal Heart Functional Measurements in a Large Brazilian Pregnant Women Sample

2018 ◽  
Vol 40 (3) ◽  
pp. 554-562 ◽  
Author(s):  
Luciane Alves Rocha ◽  
Liliam Cristine Rolo ◽  
Luciano Marcondes Machado Nardozza ◽  
Gabriele Tonni ◽  
Edward Araujo Júnior
Keyword(s):  
Pregnant Women ◽  
Fetal Heart ◽  
Reference Ranges ◽  
Z Score

Assessment of the Size and Shape of the 4-Chamber View and the Right and Left Ventricles using Fetal Speckle Tracking in Normal Fetuses at 17-24 Gestational Weeks

2021 ◽  
Author(s):  
Sanitra Anuwutnavin ◽  
Kusol Russameecharoen ◽  
Pornpimol Ruangvutilert ◽  
Sommai Viboonchard ◽  
Mark Sklansky ◽  
...  
Keyword(s):  
Speckle Tracking ◽  
Fetal Heart ◽  
Reference Intervals ◽  
Reference Ranges ◽  
Z Score ◽  
Size And Shape ◽  
Chamber View ◽  
Normal Reference ◽  
Length Width ◽  
The Right

Introduction: The aim of the study was to establish normal reference values obtained by fetal speckle tracking analysis of the fetal heart between 17-24 weeks of gestation among Thai fetuses and compare the nomograms with previous studies. Methods: The 4-chamber view of the fetal heart in 79 normal fetuses was analyzed by speckle tracking analysis to determine the best-fit regression model. The 95% reference intervals and Z-score equations of fetal cardiac parameters were computed. Results: The end-diastolic length, width, area, and circumference of the 4-chamber view (4CV) as well as the ventricular end-diastolic length, 24-segment widths, and area were all increased as a function of gestational age (GA) and 5 fetal biometric parameters. In contrast, the global sphericity index (SI), 24-segment SI, and right ventricle/left ventricle width and area ratios did not change with GA or fetal biometric measurements. There were few differences in Z-score reference ranges of fetal cardiac measurements between the current study and previous studies conducted in different patient populations. Conclusion: Our study provided z-score and corresponding centile calculators, 5th and 95th centile reference tables, and corresponding graphs for evaluating the size and shape of the 4CV and the right and left ventricles using 6 independent variables between 17 and 24 weeks of gestation. These results provide normal reference ranges for future studies of fetuses with pathologies that may alter the size and shape of the 4-chamber view and ventricles.

Z -score reference ranges for normal fetal heart sizes throughout pregnancy derived from fetal echocardiography

2014 ◽  
Vol 35 (2) ◽  
pp. 117-124 ◽  
Author(s):  
Xinyan Li ◽  
Qichang Zhou ◽  
Huan Huang ◽  
Xiaoxian Tian ◽  
Qinghai Peng
Keyword(s):  
Fetal Heart ◽  
Fetal Echocardiography ◽  
Reference Ranges ◽  
Z Score

Response to “Z-score reference ranges for normal fetal heart sizes throughout pregnancy derived from fetal echocardiography”

2016 ◽  
Vol 36 (4) ◽  
pp. 386-386
Author(s):  
Xinyan Li ◽  
Qichang Zhou ◽  
Huan Huang ◽  
Xiaoxian Tian ◽  
Qinghai Peng
Keyword(s):  
Fetal Heart ◽  
Fetal Echocardiography ◽  
Reference Ranges ◽  
Z Score

scholarly journals Wireless Fetal Heart Rate Monitoring in Inpatient Full-Term Pregnant Women: Testing Functionality and Acceptability

PLoS ONE ◽  
2015 ◽  
Vol 10 (1) ◽  
pp. e0117043 ◽  
Author(s):  
Adeline A. Boatin ◽  
Blair Wylie ◽  
Ilona Goldfarb ◽  
Robin Azevedo ◽  
Elena Pittel ◽  
...  
Keyword(s):  
Heart Rate ◽  
Pregnant Women ◽  
Fetal Heart Rate ◽  
Fetal Heart ◽  
Full Term ◽  
Heart Rate Monitoring ◽  
Fetal Heart Rate Monitoring

Fibrin monomer complex in normal pregnant women: a potential thrombotic marker in pregnancy

2007 ◽  
Vol 44 (5) ◽  
pp. 449-454 ◽  
Author(s):  
Hiroaki Onishi ◽  
Kimiko Kaniyu ◽  
Mitsutoshi Iwashita ◽  
Asashi Tanaka ◽  
Takashi Watanabe
Keyword(s):  
Pregnant Women ◽  
Late Pregnancy ◽  
Normal Pregnancy ◽  
Reference Ranges ◽  
Vein Thrombosis ◽  
Fibrin Monomer ◽  
Potential Marker ◽  
Deep Vein ◽  
Positive Results ◽  
In Pregnancy

Background: Pregnancy represents a major risk factor for deep vein thrombosis (DVT). Most coagulation/fibrinolysis markers currently utilized change during pregnancy, and therefore they cannot accurately evaluate thrombotic events in pregnancy because the rate of false positive results is high. Fibrin monomer complex (FMC) has recently become widely available for diagnosing DVT. The present study examined whether FMC is suitable for evaluating thrombotic status in pregnancy. Methods: Concentrations of FMC and other haemostatic markers were investigated in 87 pregnant women without major complications at early, mid- or late pregnancy. FMC concentrations were also measured in 127 normal non-pregnant women, and in one woman who developed DVT after delivery. Results: In normal pregnant women, FMC concentrations were unchanged during early or mid-pregnancy and slightly elevated during late pregnancy. Concentrations were within reference range in most cases, and none exceeded the cut-off value for DVT. In contrast, thrombin-antithrombin complex (TAT) and D-dimer (DD) concentrations were significantly elevated in late pregnancy, and median values exceeded reference ranges. The DVT case displayed significantly elevated FMC concentrations. Conclusions: Changes in FMC concentrations during normal pregnancy are minimal compared with other haemostatic markers. Because the rate of false positivity is lower, FMC could be a potential marker of thrombotic status in pregnancy rather than TAT and DD.

scholarly journals Reference Intervals of Thyroid Hormones and Correlation of BMI with Thyroid Function in Healthy Zhuang Ethnic Pregnant Women

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Yonghong Sheng ◽  
Dongping Huang ◽  
Shun Liu ◽  
Xuefeng Guo ◽  
Jiehua Chen ◽  
...  
Keyword(s):  
Thyroid Hormones ◽  
Pregnant Women ◽  
Thyroid Function ◽  
Reference Intervals ◽  
Thyroid Stimulating Hormone ◽  
Specific Reference ◽  
American Thyroid Association ◽  
Reference Ranges ◽  
Free Triiodothyronine ◽  
Cross Sectional

Ethnic differences in the level of thyroid hormones exist among individuals. The American Thyroid Association (ATA) recommends that an institution or region should establish a specific thyroid hormone reference value for each stage of pregnancy. To date, a limited number of studies have reported the level of thyroid hormones in Chinese minorities, and the exact relationship between BMI and thyroid function in pregnant women is ill. This study was performed to establish trimester-specific reference ranges of thyroid hormones in Zhuang ethnic pregnant women and explore the role of body mass index (BMI) on thyroid function. A total of 3324 Zhuang ethnic health pregnant women were recruited in this Zhuang population-based retrospective cross-sectional study. The values of thyroid stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) were determined by automatic chemiluminescence immunoassay analyzer. Multivariate linear regression and binary logistic regression were constructed to evaluate the influence of BMI on the thyroid function. The established reference intervals for the serum thyroid hormones in three trimesters were as follows: TSH, 0.02–3.28, 0.03–3.22, and 0.08-3.71 mIU/L; FT4, 10.57–19.76, 10.05–19.23, and 8.96–17.75 pmol/L; FT3, 3.51–5.64, 3.42–5.42, and 2.93–5.03 pmol/L. These values were markedly lower than those provided by the manufacturers for nonpregnant adults which can potentially result in 6.10% to 19.73% misclassification in Zhuang pregnant women. Moreover, BMI was positively correlated with isolated hypothyroxinemia (OR=1.081, 95% CI=1.007–1.161), while the correlation between the BMI and subclinical hypothyroidism was not statistically significant (OR=0.991, 95% CI=0.917–1.072). This is the first study focusing on the reference ranges of thyroid hormones in Guangxi Zhuang ethnic pregnant women, which will improve the care of them in the diagnosis and treatment. We also found that high BMI was positively associated with the risk of isolated hypothyroxinemia.

Feasibility of a mobile cardiotocogram device for fetal heart rate self‐monitoring in low‐risk singleton pregnant women

2021 ◽  
Author(s):  
Shunsuke Tamaru ◽  
Seung Chik Jwa ◽  
Yoshihisa Ono ◽  
Hiroyuki Seki ◽  
Haruka Matsui ◽  
...  
Keyword(s):  
Heart Rate ◽  
Pregnant Women ◽  
Fetal Heart Rate ◽  
Fetal Heart ◽  
Low Risk ◽  
Self Monitoring

Ultrasound examination of pregnant women in diagnosing fetal cardiac pathology

2020 ◽  
Vol 69 (2) ◽  
pp. 43-50
Author(s):  
Viktoria A. Lim
Keyword(s):  
Pregnant Women ◽  
Fetal Heart ◽  
Fetal Echocardiography ◽  
Heart Defects ◽  
Care Service ◽  
Ultrasound Screening ◽  
Atrioventricular Canal ◽  
Cardiac Pathology ◽  
Organ Systems ◽  
Atrioventricular Canal Defect

Hypothesis/aims of study. Fetal heart defects are the most common malformations causing infant mortality. The task of the obstetric care service is to make a timely diagnosis, which includes high-quality ultrasound screening and, if necessary, fetal echocardiography. This study aimed to compare fetal echocardiography with postpartum echocardiography. Study design, materials and methods. 101 pregnant women with both isolated fetal heart defects and combined pathology were examined for the period 20172019. Results. The greatest number of heart defects was detected at 2331 weeks of gestation. The structure of the malformations is diverse, the most common one being a complete form of the atrioventricular canal defect. In multiple pregnancies, complex heart defects were often combined with abnormalities in other organ systems. Conclusion. It is recommended to describe the heart structure in detail from 2122 weeks of pregnancy. If cardiac pathology is detected in utero, it is mandatory to conduct an examination of other fetal organs.

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