The effective use of acai juice, blueberry juice and pineapple juice as negative contrast agents for magnetic resonance cholangiopancreatography in children

2014 ◽  
Vol 44 (7) ◽  
pp. 883-887 ◽  
Author(s):  
Mark E. Bittman ◽  
Michael J. Callahan
Keyword(s):  
Magnetic Resonance ◽  
Contrast Agents ◽  
Negative Contrast ◽  
Magnetic Resonance Cholangiopancreatography ◽  
Pineapple Juice ◽  
Blueberry Juice ◽  
Effective Use

scholarly journals THE ROLE OF BLACK TEA AND PINEAPPLE JUICE AS NEGATIVE ORAL CONTRASTS ON MAGNETIC RESONANCE CHOLANGIOPANCREATOGRAPHY (MRCP) EXAMINATION

2019 ◽  
Vol 2 (3) ◽  
pp. 121
Author(s):  
Shinta J. Hapsari ◽  
Risalatul Latifah ◽  
Muhaimin Muhaimin
Keyword(s):  
Magnetic Resonance ◽  
Contrast Agents ◽  
Negative Contrast ◽  
Magnetic Resonance Cholangiopancreatography ◽  
Black Tea ◽  
Plain Water ◽  
Oral Contrast ◽  
Pineapple Juice ◽  
Long Time

Background: Magnetic resonance cholangiopancreatography examination is a superior examination in the detection of anatomic structures or pathological abnormalities in the human pancreatobiliary system. This examination is recommended to use negative oral contrast which aims to eliminate gastrointestinal signals that are around the pancreatobiliary system which can be a barrier to the visualization of the pancreatobiliary tract. Materials that can be used as oral contrast contrast must be able to survive for a long time in the gastrointestinal tract and contain elements of iron (Fe) and Manganese (Mn). The high Mn content of black and pineapple juice and its abundance need to be explored as contrast oral negative. Purpose: To prove the role of pineapple juice and black tea which are natural ingredients of negative oral contrast in the visualization of the pancreatobiliary system on MRCP examination. Methods: Experimental quasy studies have been carried out on 9 samples prospectively. Each sample underwent MRCP examination with three treatments, namely given black tea, pineapple juice and plain water. The image results from the three treatments were assessed by Radiology Doctors to assess the quality of their image. Results: The results showed that black tea was more effective in providing optimal image results on MRCP examination than pineapple juice and without using oral contrast contrast. The metal content of negative oral contrast can cause magnetic susceptibility which is characterized by the presence of shortening at the time of T2 relaxation. Negative contrast agents affect signal intensity usually by shortening T2 or T2 *, as an effect, areas of concern, especially areas with negative contrast agents will experience darkening. Conclusion: Black tea is effectively used as a negative oral contrat on MRCP examination.

scholarly journals Concurrent Dual Contrast for Cellular Magnetic Resonance Imaging Using Gadolinium Oxide and Iron Oxide Nanoparticles

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Yasir Loai ◽  
Tameshwar Ganesh ◽  
Hai-Ling Margaret Cheng
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Negative Contrast ◽  
7 Tesla ◽  
Cell Populations ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mixed Cell ◽  
Fe Oxide

Rationale and Objectives. Concurrent visualization of differential targets in cellular and molecular imaging is valuable for resolving processes spatially and temporally, as in monitoring different cell subtypes. The purpose of this study was to demonstrate concurrent, dual (positive and negative) contrast visualization on magnetic resonance imaging (MRI) of two colocalized cell populations labeled with Gadolinium “Gd” oxide and iron “Fe” oxide nanoparticles. Materials and Methods. Human aortic endothelial cells (EC) and smooth muscle cells (SMC) were labeled with various concentrations of Gd oxide and Fe oxide, respectively. MRI on single- or mixed-cell samples was performed at 7 tesla. Proper cell phenotype expressions, cell uptake of contrast agents, and the effect of labeling on cell viability and proliferation were also determined. Results. Both contrast agents were efficiently taken up by cells, with viability and proliferation largely unaffected. On MRI, the positive contrast associated with Gd oxide-labeled EC and negative contrast associated with Fe oxide-labeled SMC discriminated the presence of each cell type, whether it existed alone or colocalized in a mixed-cell sample. Conclusion. It is feasible to use Gd oxide and Fe oxide for dual contrast and concurrent discrimination of two colocalized cell populations on MRI at 7 tesla.

scholarly journals Effectiveness of Boiling Method Using Aquadest Solvent in Oolong Tea Extraction Producing Mangenese Particle as a Contrast Media on Magnetic Resonance Cholangiopancreatography (MRCP)

2021 ◽  
Vol 7 (2) ◽  
pp. 164
Author(s):  
Fatimah Fatimah ◽  
Neni Susilaningsih ◽  
Hermina Sukmaningtyas ◽  
Agus Subagio
Keyword(s):  
Magnetic Resonance ◽  
Contrast Media ◽  
Negative Contrast ◽  
Magnetic Resonance Cholangiopancreatography ◽  
Extraction Methods ◽  
Resonance Imaging ◽  
Plant Materials ◽  
Oolong Tea ◽  
Whole Process ◽  
Manganese Level

Magnetic Resonance Cholangiography (MRCP) examines the pancreas and ductus billiaris using magnetic resonance imaging with a negative contrast media administered orally. Oolong tea is possible to be an alternative of an oral negative contrast media due to its manganese contained. This study will elaborate on the best method of oolong tea extraction to get the best mangenese substance and its capability to suppress inevitable organs. This is an experimental study with various methods of extraction, which are the maceration method with ethanol solvent, maceration method with aquadest solvent, and boiling method. The whole process includes collecting and preparing plant materials, sample identification, sample processing, extraction, and extract characterization. The manganese level is checked with Atomic Absorption Spectroscopy (AAS) followed by scanning the extracted oolong tea in bottles and MRCP scanning examination. Results showed that manganese level with three different extraction methods is maceration method with ethanol is 1.23 mg/dl, maceration method with aquadest solvent is 0.82 mg/dl, and the extraction using the boiling method with aquadest solvent 0.94 mg/dl, and manufactured tea 1.40 mg/dl respectively. Scanning the extracted oolong tea in bottles showed that the best suppression is on the bottle, which contains extracted oolong tea using a boiling method with aquadest solvent. The image enhancement on MRCP showed that biliary trees are all enhanced using all the extraction methods; however, the best suppression for the stomach and duodenum is using the boiling method with aquadest solvent. The best choice for oolong tea extraction to get the best image to enhance and maximum suppression for disturbing organs is the boiling method with aquadest solvent. For the oolong tea, oral media contrast is to consider the level of manganese substance and its capability to suppress the disturbing organ to provide the best image for MRCP

Holmium phosphate nanoparticles as negative contrast agents for high-field magnetic resonance imaging: Synthesis, magnetic relaxivity study and in vivo evaluation

2021 ◽  
Vol 587 ◽  
pp. 131-140
Author(s):  
Elisabet Gómez-González ◽  
Carlos Caro ◽  
Diego Martínez-Gutiérrez ◽  
María L. García-Martín ◽  
Manuel Ocaña ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
High Field ◽  
Negative Contrast ◽  
Resonance Imaging ◽  
In Vivo Evaluation

Paramagnetic and Superparamagnetic Inorganic Nanoparticles for T1-Weighted Magnetic Resonance Imaging

2018 ◽  
Vol 25 (25) ◽  
pp. 2970-2986 ◽  
Author(s):  
Leyong Zeng ◽  
Di Wu ◽  
Ruifen Zou ◽  
Tianxiang Chen ◽  
Jinchao Zhang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Negative Contrast ◽  
Positive Contrast ◽  
Mri Contrast Agents ◽  
Inorganic Nanoparticles ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast

Magnetic resonance imaging (MRI) has become a promising technique in the early diagnosis of cancers, especially the application of contrast agents can further enhance the detection limit. Compared with the dark signal in “negative” contrast agents (T2), “positive” contrast agents (T1) with bright signal are more desirable for high-resolution imaging. However, the clinically used gadolinium complexes have short circulation time and the risk of nephrogenic system fibrosis. Therefore, to overcome the disadvantage of T2 agents and traditional T1 agents, it is very interesting to develop nano-scaled T1-weighted MRI contrast agents with safer and more precise imaging performance. The present review systematically summarized the recent progress of paramagnetic and superparamagnetic inorganic nanoparticles as T1-weighted MRI contrast agents, including gadolinium oxide nanoparticles, gadoliniumbased upconversion nanoparticles, manganese oxide nanoparticles, and ultra-small iron oxide nanoparticles. Moreover, we also described their applications in multi-modal imaging and visualized theranostics.

scholarly journals Signal suppressions of grape syrup and grape syrup/lemon aqueous solutions in magnetic resonance cholangiopancreatography using heavily T2-weighted pulse sequence

2019 ◽  
Vol 25 (3) ◽  
pp. 149-154
Author(s):  
Mahdi Asgari ◽  
Baharak Divband ◽  
Nahideh Gharehaghaji
Keyword(s):  
Gastrointestinal Tract ◽  
Magnetic Resonance ◽  
Negative Contrast ◽  
In Vitro Study ◽  
Magnetic Resonance Cholangiopancreatography ◽  
Thick Slab ◽  
Signal Suppression ◽  
Weighted Sequences ◽  
Iron And Manganese

Abstract Signal suppression of the gastrointestinal tract fluids in magnetic resonance cholangiopancreatography (MRCP) has been performed using various natural and chemical substances with the different MRCP pulse sequences. This study aimed to investigate the signal suppressions of the grape syrup and the grape syrup/lemon aqueous solutions in MRCP using the heavily T2-weighted sequences. For this purpose, the potassium, iron and manganese contents of grape syrup were measured by atomic absorption spectroscopy. The grape syrup and the grape syrup/lemon solutions with the various grape syrup percentages were imaged using the heavily T2-weighted sequences of MRCP such as T2 HASTE thick slab and T2 SPACE. MRCP in the volunteers was performed before and 10 minutes after oral administration of the grape syrup solution. The concentrations of potassium, iron, and manganese in grape syrup were 34.8, 2.4 and 1 mg/l, respectively. The in vitro study showed significantly lower signal to noise ratio using the grape syrup samples comparing to the grape syrup/lemon. The effective signal suppression for the in vitro study and considerable enhancement of negative contrast in the post-contrast MRCP was obtained using a T2 HASTE thick slab sequence. As a conclusion, the grape syrup solution can be used for signal suppression of the gastrointestinal tract fluid in MRCP as an oral negative contrast material. A T2 HASTE thick slab sequence produces suitable contrast in MRCP images using the grape syrup solution.

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