Pineapple juice labeled with gadolinium: a convenient oral contrast for magnetic resonance cholangiopancreatography

Background: Magnetic resonance cholangiopancreatography examination is a superior examination in the detection of anatomic structures or pathological abnormalities in the human pancreatobiliary system. This examination is recommended to use negative oral contrast which aims to eliminate gastrointestinal signals that are around the pancreatobiliary system which can be a barrier to the visualization of the pancreatobiliary tract. Materials that can be used as oral contrast contrast must be able to survive for a long time in the gastrointestinal tract and contain elements of iron (Fe) and Manganese (Mn). The high Mn content of black and pineapple juice and its abundance need to be explored as contrast oral negative. Purpose: To prove the role of pineapple juice and black tea which are natural ingredients of negative oral contrast in the visualization of the pancreatobiliary system on MRCP examination. Methods: Experimental quasy studies have been carried out on 9 samples prospectively. Each sample underwent MRCP examination with three treatments, namely given black tea, pineapple juice and plain water. The image results from the three treatments were assessed by Radiology Doctors to assess the quality of their image. Results: The results showed that black tea was more effective in providing optimal image results on MRCP examination than pineapple juice and without using oral contrast contrast. The metal content of negative oral contrast can cause magnetic susceptibility which is characterized by the presence of shortening at the time of T2 relaxation. Negative contrast agents affect signal intensity usually by shortening T2 or T2 *, as an effect, areas of concern, especially areas with negative contrast agents will experience darkening. Conclusion: Black tea is effectively used as a negative oral contrat on MRCP examination.

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Optimization of pineapple juice amount used as a negative oral contrast agent in magnetic resonance cholangiopancreatography

Scientific Reports ◽

10.1038/s41598-021-04609-6 ◽

2022 ◽

Vol 12 (1) ◽

Author(s):

Matteo Renzulli ◽

Daniele Caretti ◽

Irene Pettinari ◽

Maurizio Biselli ◽

Stefano Brocchi ◽

...

Keyword(s):

Magnetic Resonance ◽

Magnetic Resonance Cholangiopancreatography ◽

Absorption Spectrometry ◽

Final Concentration ◽

Oral Contrast ◽

Pineapple Juice ◽

Dose Oral ◽

Vitro Analysis ◽

In Vitro Analysis

AbstractTo evaluate the potential variability of Manganese (Mn2+) in commercial pineapple juice (PJ) produced in different years and to identify the optimal Mn2+ concentration in the correct amount of PJ to be administered prior to Magnetic Resonance Cholangiopancreatography (MRCP) in order to suppress the gastroduodenal (GD) liquid signal. The Mn2+ concentration in PJ produced in different years was defined using Atomic Absorption Spectrometry. The optimal Mn2+ concentration and the amount of PJ, were estimated in an in-vitro analysis, and were then prospectively tested in a population of patients who underwent MRCP. The results were compared with those achieved with the previous standard amount of PJ used in a similar population. The concentrations of Mn2+ in commercial PJ produced in different years did not differ. A total amount of 150 ml (one glass) of PJ having a high Mn2+ content (2.37 mg/dl) was sufficient for the suppression of the GD liquid signal, despite the additional dilution caused by GD liquids since it led to a final concentration of Mn2+ of 0.5–1.00 mg/dl. The optimized single-dose oral administration of 150 ml (approximately one glass) of PJ having a high Mn2+ concentration prior to MRCP was adequate to guarantee the correct amount of Mn2+ to suppress the GD signal.

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On the Physiology of Normal Swallowing as Revealed by Magnetic Resonance Imaging in Real Time

Gastroenterology Research and Practice ◽

10.1155/2014/493174 ◽

2014 ◽

Vol 2014 ◽

pp. 1-10 ◽

Cited By ~ 20

Author(s):

Arno Olthoff ◽

Shuo Zhang ◽

Renate Schweizer ◽

Jens Frahm

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Real Time ◽

Oral Contrast ◽

Resonance Imaging ◽

Start Time ◽

Pineapple Juice ◽

Normal Swallowing ◽

Pharyngeal Transit ◽

Pharyngeal Constriction

The aim of this study was to assess the physiology of normal swallowing using recent advances in real-time magnetic resonance imaging (MRI). Therefore ten young healthy subjects underwent real-time MRI and flexible endoscopic evaluations of swallowing (FEES) with thickened pineapple juice as oral contrast bolus. MRI movies were recorded in sagittal, coronal, and axial orientations during successive swallows at about 25 frames per second. Intermeasurement variation was analyzed and comparisons between real-time MRI and FEES were performed. Twelve distinct swallowing events could be quantified by real-time MRI (start time, end time, and duration). These included five valve functions: oro-velar opening, velo-pharyngeal closure, glottal closure, epiglottic retroflexion, and esophageal opening; three bolus transports: oro-velar transit, pharyngeal delay, pharyngeal transit; and four additional events: laryngeal ascent, laryngeal descent, vallecular, and piriform sinus filling and pharyngeal constriction. Repetitive measurements confirmed the general reliability of the MRI method with only two significant differences for the start times of the velo-pharyngeal closure (t(8)=-2.4,P≤0.046) and laryngeal ascent (t(8)=-2.6,P≤0.031). The duration of the velo-pharyngeal closure was significantly longer in real-time MRI compared to FEES (t(8)=-3.3,P≤0.011). Real-time MRI emerges as a simple, robust, and reliable tool for obtaining comprehensive functional and anatomical information about the swallowing process.

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What is the best fruit juice to use as a negative oral contrast agent in magnetic resonance cholangiopancreatography?

Clinical Radiology ◽

10.1016/j.crad.2018.11.005 ◽

2019 ◽

Vol 74 (3) ◽

pp. 220-227 ◽

Cited By ~ 3

Author(s):

M. Renzulli ◽

M. Biselli ◽

E. Fabbri ◽

D. Caretti ◽

A. Sergenti ◽

...

Keyword(s):

Magnetic Resonance ◽

Contrast Agent ◽

Fruit Juice ◽

Magnetic Resonance Cholangiopancreatography ◽

Oral Contrast ◽

Oral Contrast Agent

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Clinical Feasibility of Açai (Euterpe olerácea) Pulp as an Oral Contrast Agent for Magnetic Resonance Cholangiopancreatography

Journal of Computer Assisted Tomography ◽

10.1097/rct.0b013e31819012a0 ◽

2009 ◽

Vol 33 (5) ◽

pp. 666-671 ◽

Cited By ~ 10

Author(s):

Tiago Arruda Sanchez ◽

Jorge Elias ◽

Luiz Alberto Colnago ◽

Luiz Ernesto de Almeida Troncon ◽

Ricardo Brandt de Oliveira ◽

...

Keyword(s):

Magnetic Resonance ◽

Contrast Agent ◽

Magnetic Resonance Cholangiopancreatography ◽

Oral Contrast ◽

Euterpe Oleracea ◽

Oral Contrast Agent

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Gastric polypoid lesions detected on magnetic resonance cholangiopancreatography

10.21203/rs.3.rs-493398/v1 ◽

2021 ◽

Author(s):

Mitsuru Matsuki ◽

Isao Numoto ◽

Takefumi Hamakawa ◽

Kazunari Ishii ◽

Tomoyuki Otani

Keyword(s):

Magnetic Resonance ◽

Contrast Agent ◽

Magnetic Resonance Cholangiopancreatography ◽

Maximum Diameter ◽

Fundic Gland ◽

Oral Contrast ◽

Hyperplastic Polyps ◽

Oral Contrast Agent ◽

Fundic Gland Polyps ◽

The Mean

Abstract Background: On magnetic resonance cholangiopancreatography (MRCP) using a negative oral contrast agent, the gastric lumen appear dark, and gastric polypoid lesions can be seen. To our knowledge, there are no reports examining gastric polypoid lesions detected on MRCP.We exained the characteristics of gastric polypoid lesions detected on MRCP and discussed the management of the lesions.Material and Methods: MRCP images using a negative oral contrast agent were retrospectively evaluated in 1128 cases, and gastric polypoid lesions detected were investigated.Results: Gastric polypoid lesions were detected in 17 of the 1128 cases (1.5%) on MRCP. The mean patient age and gender were 66.7 years (range: 48-85 years) and 7 males / 10 females. A single lesion was detected in 4 cases, 2 to 4 lesions were detected in 6 cases, 5 to 10 lesions in 3 cases, and 11 or more in 4 cases. In 4 cases, the upper, middle, and lower portions of the stomach were occupied with polypoid lesions, in 4 cases, the upper and middle portions were occupied, in 1 case, the middle and lower portions were occupied, and in 8 cases, only the upper portion was occupied. One lesion was detected in 4 cases, 2 to 4 lesions were detected in 6 cases, 5 to 10 lesions in 3 cases, and 11 or more in 4 cases. The mean maximum diameter of the polypoid lesions was 7.8 mm (range: 4-16 mm). An upper endoscopy and forceps biopsy were performed in 9 of the 17 cases. The histological diagnosis was fundic gland polyps in 6 cases and hyperplastic polyps in 3 cases.Conclusion: Gastric polypoid lesions can rarely be detected on MRCP. The polypoid lesions were histologically fundic gland polyps or hyperplastic polyps. In the future, we will prospectively review more cases and examine indication of upper gastrointestinal endoscopy to gastric polypoid lesions detected on MRCP.

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