scholarly journals KIR gene content diversity in four Iranian populations

2009 ◽  
Vol 61 (7) ◽  
pp. 483-492 ◽  
Author(s):  
Elham Ashouri ◽  
Shirin Farjadian ◽  
Elaine F. Reed ◽  
Abbas Ghaderi ◽  
Raja Rajalingam
2003 ◽  
Vol 64 (10) ◽  
pp. S167 ◽  
Author(s):  
Lei Zhang ◽  
Katharine C. Hsu ◽  
Xiao-Rong Liu ◽  
Bo Dupont ◽  
Lian Fan

HLA ◽  
2018 ◽  
Vol 92 (6) ◽  
pp. 384-391
Author(s):  
Leonardo M. Amorim ◽  
Tiago H. S. Santos ◽  
Jill A. Hollenbach ◽  
Paul J. Norman ◽  
Wesley M. Marin ◽  
...  

2018 ◽  
Vol 201 (5) ◽  
pp. 1460-1467 ◽  
Author(s):  
Maria Bono ◽  
Daniela Pende ◽  
Alice Bertaina ◽  
Alessandro Moretta ◽  
Mariella Della Chiesa ◽  
...  

2014 ◽  
Vol 41 (6) ◽  
pp. 540-547 ◽  
Author(s):  
Swayam Prakash ◽  
Shahnawaz Alam ◽  
Rehan Mujeeb Faridi ◽  
Avinash Sonawane ◽  
Suraksha Agrawal

2008 ◽  
Vol 60 (12) ◽  
pp. 711-725 ◽  
Author(s):  
Richard M. Single ◽  
Maureen P. Martin ◽  
Diogo Meyer ◽  
Xiaojiang Gao ◽  
Mary Carrington

2009 ◽  
Vol 70 ◽  
pp. S85
Author(s):  
Arlene Locke ◽  
Marie Lau ◽  
John Muramoto ◽  
Elaine F. Reed ◽  
Raja Rajalingam
Keyword(s):  

PeerJ ◽  
2022 ◽  
Vol 10 ◽  
pp. e12692
Author(s):  
Jarmo Ritari ◽  
Kati Hyvärinen ◽  
Jukka Partanen ◽  
Satu Koskela

The killer cell immunoglobulin-like receptor (KIR) gene cluster on chromosome 19 encodes cell surface glycoproteins that bind class I human leukocyte antigen (HLA) molecules as well as some other ligands. Through regulation of natural killer (NK) cell activity KIRs participate in tumour surveillance and clearing viral infections. KIR gene gene copy number variation associates with the outcome of transplantations and susceptibility to immune-mediated diseases. Inferring KIR gene content from genetic variant data is therefore desirable for immunogenetic analysis, particularly in the context of growing biobank genome data collections that rely on genotyping by microarray. Here we describe a stand-alone and freely available gene content imputation for 12 KIR genes. The models were trained using 807 Finnish biobank samples genotyped for 5900 KIR-region SNPs and analysed for KIR gene content with targeted sequencing. Cross-validation results demonstrate a high mean overall accuracy of 98.5% (95% CI [97.0–99.2]%) which compares favourably with previous methods including short-read sequencing based approaches.


2012 ◽  
Vol 64 (10) ◽  
pp. 719-737 ◽  
Author(s):  
Jill A. Hollenbach ◽  
Isobel Nocedal ◽  
Martha B. Ladner ◽  
Richard M. Single ◽  
Elizabeth A. Trachtenberg

2005 ◽  
Vol 66 (8) ◽  
pp. 23
Author(s):  
M.R. Uribe ◽  
S. Adams ◽  
L. Shupert ◽  
D. Stroncek ◽  
M. Connors ◽  
...  

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