Granular cell tumor of the extremity: magnetic resonance imaging characteristics with pathologic correlation

2005 ◽  
Vol 34 (10) ◽  
pp. 625-631 ◽  
Author(s):  
Marcia F. Blacksin ◽  
Lawrence M. White ◽  
Meera Hameed ◽  
Rita Kandel ◽  
Francis R. Patterson ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Resonance Imaging ◽  
Pathologic Correlation ◽  
Imaging Characteristics

scholarly journals Granular cell tumor of the breast: correlations between imaging and pathology findings

2020 ◽  
Vol 53 (2) ◽  
pp. 105-111
Author(s):  
Natacha Abreu ◽  
Juliana Filipe ◽  
Saudade André ◽  
José Carlos Marques
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Granular Cell Tumor ◽  
Kinetic Curve ◽  
Granular Cell ◽  
Cell Tumor ◽  
Imaging Features ◽  
Resonance Imaging ◽  
Diagnostic Challenge ◽  
Picture Archiving And Communication

Abstract Objective: To review the imaging features of granular cell tumors of the breast (on mammography, ultrasound, and magnetic resonance imaging), establishing a pathological correlation, in order to familiarize radiologists with this entity and make them aware of the differential diagnoses, other than malignancy, of lesions with spiculated margins. Materials and Methods: We reviewed the medical records (from a clinical-pathology database and picture archiving and communication system) of five patients with a pathologically confirmed diagnosis of granular cell tumor of the breast, treated at the Portuguese Oncology Institute of Lisbon, in the city of Lisbon, Portugal, between January 2012 and December 2018. Results: All five tumors exhibited imaging features highly suggestive of malignancy (BI-RADS 5 lesions), namely spiculated margins, significant depth, and posterior acoustic shadowing (on ultrasound). One tumor showed a kinetic curve indicative of washout on magnetic resonance imaging, two were adherent to the pectoralis muscle, and one was accompanied by skin retraction. Pathology provided the definitive diagnosis in all cases. Conclusion: Granular cell tumors of the breast pose a diagnostic challenge because they can present with clinical and imaging features mimicking malignancy, and the diagnosis is therefore provided by pathology. Radiologists should be familiarized with this entity, so they can be aware of the fact that breast lesions with spiculated margins can be indicative of diagnoses other than malignancy.

scholarly journals Clinical features and endoscopic findings of granular cell tumor of the sellar region: A case report and review of the literature

2020 ◽  
Vol 11 ◽  
pp. 101
Author(s):  
Akari Kusakawa ◽  
Akihiro Inoue ◽  
Yawara Nakamura ◽  
Naoya Nishida ◽  
Mana Fukushima ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Anterior Pituitary ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Accurate Diagnosis ◽  
Sellar Region ◽  
Posterior Pituitary ◽  
Resonance Imaging

Background: Granular cell tumor (GCT) of the sellar region is a rare tumor of the sellar and suprasellar regions that originate from the neurohypophysis. This tumor is very difficult to differentiate from other pituitary neoplasms, such as pituitary adenoma, pituicytoma, and spindle cell oncocytoma. We report a rare case of GCT arising from the posterior pituitary of the sellar region and suggest a useful indicator for accurate diagnosis and pitfalls for surgical procedures. Case Description: A 42-year-old woman was admitted to our hospital with bitemporal hemianopsia. Neuroimaging showed a large pituitary tumor in the sellar and suprasellar regions with a hypointense part on T2-weighted magnetic resonance imaging, and the enhanced anterior pituitary gland was displaced anteriorly. Laboratory findings showed mild hyperprolactinemia. Subtotal resection of the tumor was achieved using an endoscopic endonasal transsphenoidal approach. Histological findings showed round or polygonal cells with abundant granular eosinophilic cytoplasm staining strongly for thyroid transcription factor 1. The tumor was, therefore, diagnosed as a GCT of the sellar region, belonging to tumors of the posterior pituitary. After surgery, visual impairment and anterior pituitary function were improved. Follow-up neuroimaging after 1 year showed no signs of recurrence. Conclusion: GCT of the sellar region is difficult to diagnose on routine neuroimaging. Therefore, accurate diagnosis requires careful identification of clinical signs, magnetic resonance imaging including hypointensity on T2-weighted imaging, and analysis of combined morphological and immunohistochemical studies.

Granular cell tumor of the breast: Tip and tricks on conventional and magnetic resonance imaging

2020 ◽  
Author(s):  
Giuliana Moffa ◽  
Francesca Galati ◽  
Giovanna Panzironi ◽  
Veronica Rizzo ◽  
Endi Kripa ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Resonance Imaging

Granular Cell Tumor of the Posterior Tibial Nerve as a Rare Cause of Heel Pain

2009 ◽  
Vol 99 (3) ◽  
pp. 254-257
Author(s):  
Yunus Dogramaci ◽  
Aydiner Kalaci ◽  
Teoman Toni Sevinc ◽  
Sibel Hakverdi ◽  
Serefettin Canda ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Peripheral Nerves ◽  
Granular Cell Tumor ◽  
Tibial Nerve ◽  
Granular Cell ◽  
Heel Pain ◽  
Cell Tumor ◽  
Posterior Tibial Nerve ◽  
Resonance Imaging ◽  
Posterior Tibial

Granular cell tumor of peripheral nerves is extremely rare. We present the case of a patient with a well-capsulated intraneural granular cell tumor involving the posterior tibial nerve, who presented with chronic heel pain mimicking plantar fasciitis. Magnetic resonance imaging revealed a well-defined intraneural soft-tissue mass within the substance of the posterior tibial nerve. Histopathologic examination showed a granular cell tumor, which is extremley rare in the peripheral nerves. Heel pain is one of the common conditions handled by physicians, podiatrists, and orthopedic surgeons. Posterior tibial nerve lesions at the leg should be kept in mind in the differential diagnosis of patients with persistent heel and foot pain. Magnetic resonance imaging is a useful method in the anatomical evaluation of focal intraneural lesions. (J Am Podiatr Med Assoc 99(3): 254–257, 2009)

Imaging findings of trichilemmal cyst and proliferating trichilemmal tumour

2021 ◽  
pp. 197140092110177
Author(s):  
Masaya Kawaguchi ◽  
Hiroki Kato ◽  
Natsuko Suzui ◽  
Tatsuhiko Miyazaki ◽  
Hiroyuki Tomita ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Hounsfield Units ◽  
Soft Tissue Density ◽  
Cutaneous Lesions ◽  
Imaging Characteristics ◽  
Trichilemmal Cyst ◽  
T1 Hyperintensity

Purpose The purpose of this study was to evaluate computed tomography and magnetic resonance imaging of benign trichilemmal cysts and proliferating trichilemmal tumours. Methods Nineteen histologically confirmed cutaneous lesions with trichilemmal keratinisation (12 trichilemmal cysts and seven proliferating trichilemmal tumours) were enrolled. Among them, 10 lesions (six trichilemmal cysts and four proliferating trichilemmal tumours) were examined by computed tomography, while 13 lesions (eight trichilemmal cysts and five proliferating trichilemmal tumours) were examined by magnetic resonance imaging. Computed tomography and magnetic resonance imaging characteristics were retrospectively reviewed. RESULTS Sixteen lesions (84%, 10 trichilemmal cysts and six proliferating trichilemmal tumours) occurred on the scalp. Lobulated margins were observed in five lesions (26%, three trichilemmal cysts and two proliferating trichilemmal tumours). With respect to computed tomography attenuation, calcification (>200 Hounsfield units) was observed in seven lesions (70%, five trichilemmal cysts and two proliferating trichilemmal tumours), hyperdense areas (≥80 and ≤200 Hounsfield units) in six (60%, three trichilemmal cysts and three proliferating trichilemmal tumours), and soft tissue density areas (<80 Hounsfield units) in nine (90%, five trichilemmal cysts and four proliferating trichilemmal tumours). On T1-weighted images, intratumoral hyperintensity was only observed in eight trichilemmal cysts but no proliferating trichilemmal tumours (100% vs. 0%, P<0.01). On T2-weighted images, hypointense rim and intratumoral hypointensity was observed in all 13 lesions (100%, eight trichilemmal cysts and five proliferating trichilemmal tumours), and linear or reticular hypointensity was observed in 10 (77%, six trichilemmal cysts and four proliferating trichilemmal tumours). Conclusion Trichilemmal cysts and proliferating trichilemmal tumours predominantly occurred on the scalp with calcification, and usually exhibited linear or reticular T2 hypointensity. Intratumoral T1 hyperintensity may be a useful imaging feature for differentiating trichilemmal cysts from proliferating trichilemmal tumours.

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