Added-value of ancillary imaging features for differentiating hepatocellular carcinoma from intrahepatic mass-forming cholangiocarcinoma on Gd-BOPTA-enhanced MRI in LI-RADS M

2021 ◽  
Author(s):  
Wanjing Zheng ◽  
Hongjie Huang ◽  
Dejun She ◽  
Meilian Xiong ◽  
Xiaodan Chen ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Added Value ◽  
Imaging Features ◽  
Enhanced Mri

scholarly journals Prediction of Microvascular Invasion in Hepatocellular Carcinoma: Preoperative Gd-EOB-DTPA-Dynamic Enhanced MRI and Histopathological Correlation

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Mengqi Huang ◽  
Bing Liao ◽  
Ping Xu ◽  
Huasong Cai ◽  
Kun Huang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Prediction Model ◽  
Tumor Size ◽  
Univariate Analysis ◽  
Microvascular Invasion ◽  
Arterial Phase ◽  
Hepatobiliary Phase ◽  
Imaging Features ◽  
Tumor Margin ◽  
Enhanced Mri

Objective. To investigate the imaging features observed in preoperative Gd-EOB-DTPA-dynamic enhanced MRI and correlated with the presence of microvascular invasion (MVI) in hepatocellular carcinoma (HCC) patients. Methods. 66 HCCs in 60 patients with preoperative Gd-EOB-DTPA-dynamic enhanced MRI were retrospectively analyzed. Features including tumor size, signal homogeneity, tumor capsule, tumor margin, peritumor enhancement during mid-arterial phase, peritumor hypointensity during hepatobiliary phase, signal intensity ratio on DWI and apparent diffusion coefficients (ADC), T1 relaxation times, and the reduction rate between pre- and postcontrast enhancement images were assessed. Correlation between these features and histopathological presence of MVI was analyzed to establish a prediction model. Results. Histopathology confirmed that MVI were observed in 17 of 66 HCCs. Univariate analysis showed tumor size (p=0.003), margin (p=0.013), peritumor enhancement (p=0.001), and hypointensity during hepatobiliary phase (p=0.004) were associated with MVI. A multiple logistic regression model was established, which showed tumor size, margin, and peritumor enhancement were combined predictors for the presence of MVI (α=0.1). R2 of this prediction model was 0.353, and the sensitivity and specificity were 52.9% and 93.0%, respectively. Conclusion. Large tumor size, irregular tumor margin, and peritumor enhancement in preoperative Gd-EOB-DTPA-dynamic enhanced MRI can predict the presence of MVI in HCC.

Detection of hepatocellular carcinoma (HCC) using super paramagnetic iron oxide (SPIO)-enhanced MRI: Added value of diffusion-weighted imaging (DWI)

2010 ◽  
Vol 31 (2) ◽  
pp. 373-382 ◽  
Author(s):  
Akihiro Nishie ◽  
Tsuyoshi Tajima ◽  
Kousei Ishigami ◽  
Yasuhiro Ushijima ◽  
Daisuke Okamoto ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Iron Oxide ◽  
Diffusion Weighted Imaging ◽  
Added Value ◽  
Super Paramagnetic Iron Oxide ◽  
Enhanced Mri ◽  
Diffusion Weighted

Added value of smooth hypointense rim in the hepatobiliary phase of gadoxetic acid-enhanced MRI in identifying tumour capsule and diagnosing hepatocellular carcinoma

2016 ◽  
Vol 27 (6) ◽  
pp. 2610-2618 ◽  
Author(s):  
Chansik An ◽  
Hyungjin Rhee ◽  
Kyunghwa Han ◽  
Jin-Young Choi ◽  
Young-Nyun Park ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gadoxetic Acid ◽  
Added Value ◽  
Hepatobiliary Phase ◽  
Enhanced Mri

scholarly journals Can LI-RADS imaging features at gadoxetic acid-enhanced MRI predict aggressive features on pathology of single hepatocellular carcinoma?

2020 ◽  
Vol 132 ◽  
pp. 109312
Author(s):  
Hong Wei ◽  
Hanyu Jiang ◽  
Xijiao Liu ◽  
Yun Qin ◽  
Tianying Zheng ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gadoxetic Acid ◽  
Imaging Features ◽  
Enhanced Mri

Intra-individual comparison of hepatocellular carcinoma imaging features on contrast-enhanced computed tomography, gadopentetate dimeglumine-enhanced MRI, and gadoxetic acid-enhanced MRI

2017 ◽  
Vol 59 (6) ◽  
pp. 639-648 ◽  
Author(s):  
Yo Na Kim ◽  
Ji Soo Song ◽  
Woo Sung Moon ◽  
Hong Pil Hwang ◽  
Young Kon Kim
Keyword(s):  
Computed Tomography ◽  
Hepatocellular Carcinoma ◽  
Contrast Ratio ◽  
Gadopentetate Dimeglumine ◽  
Gadoxetic Acid ◽  
Arterial Phase ◽  
Hepatobiliary Phase ◽  
Imaging Features ◽  
Enhanced Mri ◽  
Individual Comparison

Background Gadoxetic acid is being widely used for detection and characterization of hepatic nodules. However, there are no data regarding intra-individual comparison of imaging features of hepatocellular carcinoma (HCC) on dynamic computed tomography (CT), gadopentetate dimeglumine-enhanced magnetic resonance imaging (Gd-DTPA-MRI), and gadoxetic acid-enhanced MRI (Gd-EOB-MRI). Purpose To evaluate typical imaging features of HCC and capsule appearance with dynamic CT, Gd-DTPA-MRI, and Gd-EOB-MRI. Material and Methods We retrospectively reviewed 56 HCCs in 49 patients. Lesion attenuation/signal intensity was graded using a five-point scale based on dynamic phase and hepatobiliary phase (HBP) imaging. Subjective washout and capsule appearance were evaluated on portal venous phase (PVP) or delayed/transitional phase (DP/TP) imaging. The tumor-to-liver contrast ratio (TLCR) was calculated. Results Gd-DTPA-MRI and Gd-EOB-MRI was graded higher than CT on arterial phase ( P < 0.001). Gd-EOB-MRI was graded lower than Gd-DTPA-MRI on PVP and DP/TP ( P < 0.05). The detection rate of subjective washout and capsule appearance did not differ among the three imaging studies on either PVP or DP/TP. TLCR of Gd-EOB-MRI was lower than CT on PVP ( P = 0.004) and was lower than Gd-DTPA-MRI on DP/TP ( P = 0.001). Conclusion Arterial phase hyperenhancement and washout appearance of HCC were well demonstrated in Gd-EOB-MRI. The detection of capsule appearance using Gd-EOB-MRI was not inferior to Gd-DTPA-MRI or CT.

scholarly journals Imaging features of fibrolamellar hepatocellular carcinoma in gadoxetic acid-enhanced MRI

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Viktoria Palm ◽  
Ruofan Sheng ◽  
Philipp Mayer ◽  
Karl-Heinz Weiss ◽  
Christoph Springfeld ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gadoxetic Acid ◽  
Imaging Features ◽  
Fibrolamellar Hepatocellular Carcinoma ◽  
Enhanced Mri

Added value of ancillary imaging features for differentiating scirrhous hepatocellular carcinoma from intrahepatic cholangiocarcinoma on gadoxetic acid-enhanced MR imaging

2018 ◽  
Vol 28 (6) ◽  
pp. 2549-2560 ◽  
Author(s):  
Seo-Youn Choi ◽  
Young Kon Kim ◽  
Ji Hye Min ◽  
Tae Wook Kang ◽  
Woo Kyoung Jeong ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Mr Imaging ◽  
Intrahepatic Cholangiocarcinoma ◽  
Gadoxetic Acid ◽  
Added Value ◽  
Imaging Features
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