A Perioperative Small Dose of Dexamethasone Enhances Postoperative Recovery by Reducing Volume and Inflammatory Contents in Wound Drainage After Thyroid Surgery: A Double-Blinded, Randomized, Prospective Study

2019 ◽  
Vol 43 (7) ◽  
pp. 1721-1727 ◽  
Author(s):  
Huiwen Zhang ◽  
Jie Lu ◽  
Qiang Wu ◽  
Bo Wu ◽  
Cheng Xu ◽  
...  
2015 ◽  
Vol 23 (3) ◽  
pp. 99-103
Author(s):  
Somesh Mozumder ◽  
Shirish Dubey ◽  
Aniruddha Dam ◽  
Anup Kumar Bhowmick

Introduction: Recurrent laryngeal nerves (RLN) are particularly prone to injury during thyroid surgeries due to its intimate relationship and proximity with the gland. Zuckerkandl’s tubercle (ZT) helps in preserving RLN intra operative. Material and Methods: A prospective study for identifying RLN in thyroid surgery using relationship with superior parathyroid gland and tubercle of Zuckerkandl was conducted on 50 thyroidectomy patients between August 2013 and February 2014. Results: In all cases ZT was identified. Temporary paralysis of RLN was seen in 3 (6%) cases and permanent paralysis in 2 (4%) of cases. Discussion: The site of greatest risk during thyroidectomy to the RLN is in the last 2-3 cm extralaryngeal course of the nerve. Relationship of recurrent laryngeal nerve with superior parathyroid gland and tubercle of Zukerkandl (ZT) is known. Conclusion: Use of ZT and superior parathyroids as a landmark allows safe dissection of RLN.


2021 ◽  
Vol 8 (31) ◽  
pp. 2900-2905
Author(s):  
Sadhu Nagamuneiah ◽  
Gandikota Venkata Prakash ◽  
Sabitha P ◽  
Karthik Periyasamy ◽  
Sanjay Raj Kumar Reddy Madduri ◽  
...  

BACKGROUND Thyroidectomy is a surgical procedure which is commonly performed by surgeons worldwide, but the outcome and complication rates were mainly dependent on the surgeon’s skill and experience, indication and the extent of surgery and the number of thyroid surgeries performed at that particular centre. The aim of this study was to assess the frequency of the postoperative complications after thyroid surgery in Sri Venkateswara Ramnaraian Ruiya Government General Hospital, Tirupati. METHODS A prospective study conducted on 100 patients with thyroid swelling who attended the Sri Venkateshwara Ramnaraian Ruya Government General Hospital, Tirupati. Patient age, sex, rural/urban origin, history, diagnosis, type of surgery, laboratory investigation such as complete blood, serum calcium, thyroid function test, us culture and sensitivity test in wound infections and indirect laryngoscopy for all pre-operative patients and postoperative voice change patients. Outcomes recorded as a complication of thyroid surgery within one week. RESULTS Totally 100 patients were enrolled in the study. Thyroid enlargement was more common in females (F: M =5.6:1) presenting in 3rd and 4th decades mostly with the mean age and standard deviation were 42.92 years and 13.097 years respectively. Total thyroidectomy was the most common procedure performed (44 %) followed by hemithyroidectomy (31 %), subtotal thyroidectomies (29 %) and near total thyroidectomy (5 %). On histopathological examination most common finding was multinodular goiter (54 %) followed by nodular goiter (33 %) and malignancies (10 %). The overall postoperative complication rate was 47 %. The most common postoperative complications after thyroidectomies were seroma formation in wound complication (27 %), followed by hypocalcemia (11 %), recurrent laryngeal nerve (RLN) injury (3 %), and surgical site infection (2 %). Majority of these complications were found to be associated with total thyroidectomy, female population, and in patients with age more than 30 years. CONCLUSIONS Seroma formation in wound complication is the commonest post thyroidectomy complication. Female gender, old age, and extensive thyroid surgery were associated with increased complication rate. KEYWORDS Post-Operative Complications, Thyroid Surgery


2001 ◽  
Vol 94 (4) ◽  
pp. 574-578 ◽  
Author(s):  
Marc De Kock ◽  
Philippe Gautier ◽  
Luc Fanard ◽  
Jean Luc Hody ◽  
Patricia Lavand’homme

Background The aim of this study was to evaluate the association of a small dose of intrathecal ropivacaine with small doses of intrathecal clonidine for ambulatory surgery. Methods One hundred twenty patients, classified as American Society of Anesthesiologists physical status I and scheduled for knee arthroscopy, were studied. Patients were randomly assigned to receive 4 ml of one of the following double-blinded isobaric intrathecal solutions: 8 mg of ropivacaine (group 1; n =30); 8 mg ropivacaine plus 15 microg clonidine (group 2; n =30); 8 mg ropivacaine plus 45 microg clonidine (group 3; n =30); and 8 mg ropivacaine plus 75 microg clonidine (group 4; n =30). The level and duration of sensory anesthesia were recorded, along with the intensity and duration of motor block. Patient and surgeon were interviewed to evaluate the quality of anesthesia. Results Intrathecal ropivacaine (8 mg alone) produced short sensory anesthesia and motor blockade (132 +/- 38 min and 110 +/- 35 min; mean +/- SD). However, the quality of anesthesia was significantly lower than in any other group (P < 0.05). Ropivacaine (8 mg) plus 75 microg clonidine produced significantly longer sensory and motor anesthesia (195 +/- 40 min and 164 +/- 38 min; P < 0.05). However, this was associated with systemic effects, such as sedation and reduction of arterial blood pressure. Ropivacaine (8 mg) plus 15 microg clonidine did not prolong sensory or motor blockade, afforded high quality anesthesia, and was not associated with detectable systemic effects. Conclusion Small-dose intrathecal clonidine (15 microg) plus 8 mg intrathecal ropivacaine produces adequate and short-lasting anesthesia for knee arthroscopy.


2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Thalia W. Malingkas ◽  
Stefana H. M. Kaligis ◽  
Murniati Tiho

Abstract: Many studies showed that antioxidants contained polyphenols and flavonoids such as red wine could reduce the risk of cardiovascular disease. This study’s purpose is to determine the effect of red wine on cardiovascular health. This is a literature review using three databases: Pubmed, Google Scholar and Clinical Key. The keywords using to search the articles are red wine AND cardiovascular disease AND antioxidant OR antioksidan AND flavonoid. After being selected based on inclusion and exclusion criteria, ten literatures were found. The research methods using in the literatures were very varied, which were a cross-over study, single blind cross-over, double-blinded, comprised two study days, parallel four-armed intervention, experimental, randomized, and prospective study. The subjects in these studies were also varied, from healthy people to people with cardiovascular disorders and with other health problems. Besides red wine, interventions with dealcoholized red wine and red grape polyphenol extract (RGPE) also were used in some studies. However, the results from all studies showed that consuming red wine has a good effect on cardiovascular health, measured from LDL and HDL blood level, FMD and systolic blood pressure. In conclusion, red wine consumption has beneficial effects on cardiovascular health.Keywords: red wine, antioxidant, cardiovascular health, polyphenol, flavonoid  Abstrak: Banyak penelitian menunjukkan bahwa antioksidan yang mengandung polifenol dan flavonoid seperti red wine dapat menurunkan risiko penyakit kardiovaskular. Tujuan penelitian ini untuk mengetahui efek red wine terhadap kesehatan kardiovaskular. Penelitian ini berbentuk literature review menggunakan tiga database yaitu Pubmed, Google Scholar, dan Clinical Key.  Kata kunci yang digunakan dalam pencarian artikel yaitu red wine AND cardiovascular disease AND antioxidant OR antioksidan AND flavonoid. Setelah diseleksi berdasarkan kriteria inklusi dan eksklusi, didapatkan 10 literatur yang memenuhi kriteria. Literatur-literatur yang ditemukan menggunakan metode penelitian beragam yaitu cross-over study, single blind cross-over, double-blinded, comprised two study days, parallel four-armed intervention, experimental, randomized, dan prospective study. Subjek yang berpartisipasi dalam studi-studi tersebut juga bervariasi, yaitu terdiri dari orang yang sehat, orang dengan ganguan kardiovaskular dan orang dengan gangguan kesehatan lainnya. Selain red wine, intervensi menggunakan dealcoholized red wine, dan red grape polyphenol extract (RGPE) juga dilakukan pada beberapa studi. Meskipun demikian, hasil yang didapatkan dari semua studi menunjukkan bahwa mengonsumsi red wine memberikan efek yang baik terhadap kesehatan kardiovaskular, yang dilihat dari pengukuran LDL dan HDL darah, FMD dan systolic blood pressure. Sebagai simpulan konsumsi red wine memberikan efek yang bermanfaat bagi kesehatan kardiovaskular.Kata Kunci: red wine, antioksidan, kesehatan kardiovaskular, polifenol, flavonoid


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