scholarly journals Efek Red Wine Terhadap Kesehatan Kardiovaskular

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Thalia W. Malingkas ◽  
Stefana H. M. Kaligis ◽  
Murniati Tiho

Abstract: Many studies showed that antioxidants contained polyphenols and flavonoids such as red wine could reduce the risk of cardiovascular disease. This study’s purpose is to determine the effect of red wine on cardiovascular health. This is a literature review using three databases: Pubmed, Google Scholar and Clinical Key. The keywords using to search the articles are red wine AND cardiovascular disease AND antioxidant OR antioksidan AND flavonoid. After being selected based on inclusion and exclusion criteria, ten literatures were found. The research methods using in the literatures were very varied, which were a cross-over study, single blind cross-over, double-blinded, comprised two study days, parallel four-armed intervention, experimental, randomized, and prospective study. The subjects in these studies were also varied, from healthy people to people with cardiovascular disorders and with other health problems. Besides red wine, interventions with dealcoholized red wine and red grape polyphenol extract (RGPE) also were used in some studies. However, the results from all studies showed that consuming red wine has a good effect on cardiovascular health, measured from LDL and HDL blood level, FMD and systolic blood pressure. In conclusion, red wine consumption has beneficial effects on cardiovascular health.Keywords: red wine, antioxidant, cardiovascular health, polyphenol, flavonoid  Abstrak: Banyak penelitian menunjukkan bahwa antioksidan yang mengandung polifenol dan flavonoid seperti red wine dapat menurunkan risiko penyakit kardiovaskular. Tujuan penelitian ini untuk mengetahui efek red wine terhadap kesehatan kardiovaskular. Penelitian ini berbentuk literature review menggunakan tiga database yaitu Pubmed, Google Scholar, dan Clinical Key.  Kata kunci yang digunakan dalam pencarian artikel yaitu red wine AND cardiovascular disease AND antioxidant OR antioksidan AND flavonoid. Setelah diseleksi berdasarkan kriteria inklusi dan eksklusi, didapatkan 10 literatur yang memenuhi kriteria. Literatur-literatur yang ditemukan menggunakan metode penelitian beragam yaitu cross-over study, single blind cross-over, double-blinded, comprised two study days, parallel four-armed intervention, experimental, randomized, dan prospective study. Subjek yang berpartisipasi dalam studi-studi tersebut juga bervariasi, yaitu terdiri dari orang yang sehat, orang dengan ganguan kardiovaskular dan orang dengan gangguan kesehatan lainnya. Selain red wine, intervensi menggunakan dealcoholized red wine, dan red grape polyphenol extract (RGPE) juga dilakukan pada beberapa studi. Meskipun demikian, hasil yang didapatkan dari semua studi menunjukkan bahwa mengonsumsi red wine memberikan efek yang baik terhadap kesehatan kardiovaskular, yang dilihat dari pengukuran LDL dan HDL darah, FMD dan systolic blood pressure. Sebagai simpulan konsumsi red wine memberikan efek yang bermanfaat bagi kesehatan kardiovaskular.Kata Kunci: red wine, antioksidan, kesehatan kardiovaskular, polifenol, flavonoid

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Mei Zhang ◽  
Yu Shi ◽  
Oumin Shi ◽  
Zhenping Zhao ◽  
Xiao Zhang ◽  
...  

Background: Cardiovascular disease is the leading cause of death in China. Objectives: We aimed to evaluate the levels of cardiovascular health among Chinese adults and to understand the geographic patterns based on a nationally and provincially representative survey. Methods: In 2015, a total of 74,771 respondents aged ≥ 20 years with no history of cardiovascular disease were randomly sampled from 298 counties/districts of 31 provinces in mainland China and were interviewed. Seven metrics, including smoking, body mass index, physical activity, diet, total cholesterol, blood pressure, and fasting glucose, were determined. Ideal cardiovascular health was defined as the simultaneous presence of all metrics at the ideal level. A score ranging from 0 to 14 was calculated as the sum of all seven metrics for each province. Scores for four health behaviors and four health factors were also calculated. Results: The age-adjusted prevalence of ideal cardiovascular health was only 1.13% among Chinese adults above 20 years old in 2015 (0.50% among men and 1.77% among women; 1.63% among urban residents and 0.68% among rural residents). The age-adjusted prevalence varied greatly across provinces, ranging from 0.05% in Qinghai to 2.97% in Heilongjiang. Ideal diet (7.4%) was the least common among seven cardiovascular health metrics and ideal blood pressure (32.2%) was the second least one. We also saw significant heterogeneity among provinces in age-adjusted cardiovascular health score, health behavior score, and health factors score. In all provinces, women had higher scores than men for cardiovascular health, health behaviors and health factors. Differences in cardiovascular health and health behavior scores between urban and rural areas were associated with levels of socio-economic development. Conclusions: Strategies for addressing poor cardiovascular health require geographic targeting and localized consideration.


2020 ◽  
Vol 16 (1) ◽  
pp. 53-60
Author(s):  
Enrique Gómez-Álvarez ◽  
Juan Verdejo ◽  
Salvador Ocampo ◽  
Emilio Ruiz ◽  
Marco A Martinez-Rios

Aim: To determine the effectiveness of Centro Nacional de Investigaciones Cardiovasculares (CNIC)-polypill (acetylsalicylic acid 100 mg, ramipril 5/10 mg, simvastatin 40 mg) in achieving blood pressure (BP) goals. Patients & methods: A multicenter, observational, one cohort, prospective study. BP targets were analyzed in patients with cardiovascular disease after 12-months treatment with the CNIC polypill. Results: A total of 572 patients (59.4 ± 13.9 years, 57.3% men) were analyzed. At baseline, BP was 147.1 ± 18.1/88.3 ± 10.6 mmHg, 97.1% of patients were taken renin-angiotensin system inhibitors, 5.4% calcium antagonists, 1.9% diuretics and 13.1% β-blockers. The proportion of patients who achieved BP targets increased from 20.1 to 55.4% (p < 0.001). Conclusion: In routine practice, switching from usual care to the CNIC-polypill in patients with cardiovascular disease could facilitate achieving BP goals.


2021 ◽  
Vol 3 ◽  
Author(s):  
Joe Steinman ◽  
Andrew Barszczyk ◽  
Hong-Shuo Sun ◽  
Kang Lee ◽  
Zhong-Ping Feng

Regular blood pressure (BP) monitoring enables earlier detection of hypertension and reduces cardiovascular disease. Cuff-based BP measurements require equipment that is inconvenient for some individuals and deters regular home-based monitoring. Since smartphones contain sensors such as video cameras that detect arterial pulsations, they could also be used to assess cardiovascular health. Researchers have developed a variety of image processing and machine learning techniques for predicting BP via smartphone or video camera. This review highlights research behind smartphone and video camera methods for measuring BP. These methods may in future be used at home or in clinics, but must be tested over a larger range of BP and lighting conditions. The review concludes with a discussion of the advantages of the various techniques, their potential clinical applications, and future directions and challenges. Video cameras may potentially measure multiple cardiovascular metrics including and beyond BP, reducing the risk of cardiovascular disease.


Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Luc Djousse ◽  
Andrew Petrone ◽  
Chad Blackshear ◽  
Michael Griswold ◽  
Jane Harman ◽  
...  

Background: While the prevalence of cardiovascular health metrics or Life’s Simple Seven (LSS) has been shown to be far from optimal in the US, such information has been predominantly reported in Caucasians. The burden of cardiovascular disease among African Americans underscores the need to evaluate the prevalence and secular trends of LSS in other ethnic groups. Objective: To test the hypothesis that the prevalence of the LSS is far from ideal among participants of the Jackson Heart Study. Methods: We analyzed LSS with 3,500 African Americans from the Jackson Heart Study, using data from their first clinic visit (2000-2004). Standard methods were used to measure blood pressure, glucose, body mass index (BMI), and cholesterol. Information on physical activity, smoking, and diet was collected with interviewer-administered questionnaires. Each of the LSS metrics (smoking status, diet, physical activity, BMI, fasting blood glucose, total cholesterol, and blood pressure) was categorized as poor, intermediate, or ideal, as defined by the AHA guidelines. Results: The mean age at baseline was 56.9 ± 12.2 years and 2,350 participants (67%) were women. Among men, the prevalence of having 0, 1, 2, 3, 4, 5, 6, and 7 ideal cardiovascular health metrics was 6.6%, 25.8%, 32.7%, 21.6%, 10.6%, 2.3%, 0.4%, and 0%, respectively. Corresponding values for women were 3.2%, 28.1%, 32.9%, 22.3%, 10.1%, 2.9%, 0.38%, and 0%. While about two-thirds of men and women reported ideal smoking status, almost none reported ideal diet quality, and few met recommendations for BMI and blood pressure ( Figure) . Conclusions: Our data are consistent with less than optimal prevalence of cardiovascular health metrics in both men and women from the Jackson Heart Study. The lower prevalence of meeting ideal recommendations for diet, physical activity, BMI, and blood pressure underscores the need for targeted interventions to improve these modifiable lifestyle factors in order to reduce the burden of cardiovascular disease among African-Americans.


1989 ◽  
Vol 130 (4) ◽  
pp. 646-654 ◽  
Author(s):  
NICHOLAS H. FLEBACH ◽  
PATRICIA R. HEBERT ◽  
MELR J STAMPFER ◽  
GRAHAM A. COLDITZ ◽  
WALTER C. WILLETT ◽  
...  

2019 ◽  
Vol 11 (3) ◽  
pp. 68
Author(s):  
Naa-Solo Tettey

INTRODUCTION: Chronic illnesses, such as heart disease, affect African Americans at disproportionately higher rates due in part to low health literacy and a lack of comprehensive health education programs. PURPOSE: The purpose of this research is to demonstrate the effectiveness of HeartSmarts, a culturally tailored, comprehensive cardiovascular health education program, in improving cardiovascular health literacy. METHODS: Peer health educators were trained to deliver an extensive curriculum focused on cardiovascular disease and its risk factors. Upon completion, they delivered this curriculum in their churches and communities. Pre- and post-assessments were administered for blood pressure, weight, waist circumference, and knowledge of cardiovascular disease. RESULTS: Fourteen predominantly African American churches in New York City participated, and 199 participants completed the program. Participants experienced decreases in blood pressure and weight, improved their health-related behaviors, and significantly increased their knowledge of cardiovascular health. CONCLUSION: The HeartSmarts program demonstrates the effectiveness of using a comprehensive health education approach to help combat these issues. Programs that use strategies similar to HeartSmarts should be implemented for other health conditions to decrease health disparities.


2021 ◽  
Author(s):  
Bamba Gaye ◽  
Donald Lloyd-Jones ◽  
Eugenie Valentin ◽  
Joshua J Joseph ◽  
Xavier Jouven ◽  
...  

Abstract Objective: To describe patterns of change in cardiovascular health (CVH) measured by the Life’s Simple 7 (LS7) over 6 years in participants with diabetes, and assess the association of these patterns of change with subsequent cardiovascular disease (CVD) and all-cause mortality.Methods: We conducted a long-term prospective cohort analysis (median follow-up 19 years) using the ARIC study, a community-based, biracial cohort with participants aged 45-64 years at baseline in 1987–1989. The LS7 metrics (smoking, body mass index, physical activity, diet, total cholesterol, blood glucose, and blood pressure) were collected at baseline and 6 years later. At both time points, participants were classified as low (0-2 ideal metrics), moderate (3-4), and favorable (5-7) CVH, and 6-year CVH change categories were created. Cox proportional hazards regressions were used to estimate the association between change categories and CVD and mortality. Results: The majority (62.2%) of participants with diabetes had a stable-low CVH at both visits, whereas 12.1% had stable-moderate and 0.4% stable-favorable, 14.9% improved, and 10.5% worsened. Compared to participants with stable-low CVH, CVD and mortality risk was lower for those who improved CVH 6 years later, or stable-moderate, or even high- or moderate-to-low CVH. This was driven by favorable changes in blood pressure, cholesterol, physical activity and smoking. Compared to participants free of diabetes with a stable-favorable CVH change, participants with diabetes had higher CVD and mortality risk regardless of their CVH trajectory. However, those with a favorable CVH trajectory displayed the same excess risk as participants without diabetes with stable-low CVH. Conclusions: Among individuals with diabetes, maintaining or reaching ideal levels of LS7 metrics can help reduce the excess CVD incidence and mortality. A favorable CVH trajectory in people with diabetes carried approximately the same excess CVD and mortality risk than an unfavorable CVH trajectory in people free of diabetes.


2005 ◽  
Vol 59 (3) ◽  
pp. 449-455 ◽  
Author(s):  
A S Hansen ◽  
P Marckmann ◽  
L O Dragsted ◽  
I -L Finné Nielsen ◽  
S E Nielsen ◽  
...  

BMJ Open ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. e036394
Author(s):  
Wuxiang Xie ◽  
Yanfang Wang ◽  
Jianqin Sun ◽  
Guo Zeng ◽  
Huilian Zhu ◽  
...  

IntroductionUnhealthy diet has been identified as the number one attributor of total mortality in China, accounting for more than 20% of total deaths. Although the Dietary Approach to Stop Hypertension (DASH) and Mediterranean diets have been proven beneficial in managing cardiovascular risk factors in Western countries, whether healthy diets with similar cardiovascular benefits can be developed that are consistent with Chinese food culture remains unknown.Methods/designThe Diet, ExerCIse and CarDiovascular hEalth (DECIDE)-Diet trial is a multicentre, single-blind, randomised controlled feeding trial to evaluate the effect of the Chinese Healthy Heart (CHH) diet, in comparison with the Chinese usual diet, in lowering cardiovascular risk factors among community residents with the increased cardiovascular risk. A total of 360 adults aged between 25 and 75 years old and with systolic blood pressure between 130 and 159 mm Hg will be recruited from four centres located in four areas representing four major Chinese cuisines: Beijing, Shanghai, Guangzhou and Chengdu. After 1 week of run-in period with local usual diet, the compliant participants will be randomised to the intervention group with the CHH diet or the control group with the usual local diet, on a 1:1 ratio, for 4 weeks. Body weight of study participants will be maintained during the entire study period. The primary outcome is the change in SBP from the baseline to the end of the study. DECIDE-Diet trial will be the first randomised controlled feeding trial to evaluate the effect of a CHH diet in lowering cardiovascular risk factors. This trial will provide compelling evidence on the CHH diet in effect of improving cardiovascular health among Chinese food consumers all around the world.Ethics and disseminationThis trial adheres to the Declaration of Helsinki and guidelines of Good Clinical Practice. Signed informed consent will be obtained from all participants. The trial has been approved by the Peking University Institutional Review Board (approval number: IRB00001052-18094). The results will be disseminated through academic conferences and publications in international peer-reviewed journals.Trail registration numberClinicalTrials.gov Registry (NCT03882645); Pre-results.


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