Molecular classification of tumors with special reference to EGFR mutation in lung cancer

2006 ◽  
Vol 58 (S1) ◽  
pp. 17-23 ◽  
Author(s):  
Yasushi Yatabe
Author(s):  
Jaime Rodriguez-Canales ◽  
Edwin Parra-Cuentas ◽  
Ignacio I. Wistuba

Cancer ◽  
2011 ◽  
Vol 118 (6) ◽  
pp. 1607-1618 ◽  
Author(s):  
Valsamo K. Anagnostou ◽  
Anastasios T. Dimou ◽  
Taxiarchis Botsis ◽  
Elizabeth J. Killiam ◽  
Mark D. Gustavson ◽  
...  

Author(s):  
Mark E. Sherman ◽  
Melissa A. Troester ◽  
Katherine A. Hoadley ◽  
William F. Anderson

Accurate and reproducible classification of tumors is essential for clinical management, cancer surveillance, and studies of pathogenesis and etiology. Tumor classification has historically been based on the primary anatomic site or organ in which the tumor occurs and on its morphologic and histologic phenotype. While pathologic criteria are useful in predicting the average behavior of a group of tumors, histopathology alone cannot accurately predict the prognosis and treatment response of individual cancers. Traditional measures such as tumor stage and grade do not take into account molecular events that influence tumor aggressiveness or changes in the tumor composition during treatment. This chapter provides a primer on approaches that use pathology and molecular biology to classify and subclassify cancers. It describes the features of carcinomas, sarcomas, and malignant neoplasms of the immune system and blood, as well as various high-throughput genomic platforms that characterize the molecular profile of tumors.


2004 ◽  
Vol 10 (9) ◽  
pp. 2922-2927 ◽  
Author(s):  
Giovanni Parmigiani ◽  
Elizabeth S. Garrett-Mayer ◽  
Ramaswamy Anbazhagan ◽  
Edward Gabrielson

Diagnostics ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 2326
Author(s):  
David Creytens

Soft tissue and bone tumors constitute a large and heterogeneous group of tumors comprising >100 distinct histological types and subtypes, which are diagnosed and classified using criteria from the World Health Organization (WHO) Classification of Tumors [...]


CHEST Journal ◽  
2004 ◽  
Vol 125 (5) ◽  
pp. 103S ◽  
Author(s):  
Giovanni Parmigiani ◽  
Elizabeth Garrett ◽  
Ramaswamy Anbazhagan ◽  
Edward Gabrielson

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