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Phase I study of chidamide (CS055/HBI-8000), a new histone deacetylase inhibitor, in patients with advanced solid tumors and lymphomas
Cancer Chemotherapy and Pharmacology
◽
10.1007/s00280-012-1847-5
◽
2012
◽
Vol 69
(6)
◽
pp. 1413-1422
◽
Cited By ~ 51
Author(s):
Mei Dong
◽
Zhi-Qiang Ning
◽
Pu-Yuan Xing
◽
Jia-Lian Xu
◽
Hai-Xiang Cao
◽
...
Keyword(s):
Phase I
◽
Solid Tumors
◽
Histone Deacetylase
◽
Histone Deacetylase Inhibitor
◽
Phase I Study
◽
Advanced Solid Tumors
◽
Deacetylase Inhibitor
Download Full-text
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A Phase I Study of Quisinostat (JNJ-26481585), an Oral Hydroxamate Histone Deacetylase Inhibitor with Evidence of Target Modulation and Antitumor Activity, in Patients with Advanced Solid Tumors
Clinical Cancer Research
◽
10.1158/1078-0432.ccr-13-0312
◽
2013
◽
Vol 19
(15)
◽
pp. 4262-4272
◽
Cited By ~ 63
Author(s):
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◽
Richard Baird
◽
Rebecca S. Kristeleit
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Antitumor Activity
◽
Phase I
◽
Solid Tumors
◽
Histone Deacetylase
◽
Histone Deacetylase Inhibitor
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First-in-human, Pharmacokinetic and Pharmacodynamic Phase I Study of Resminostat, an Oral Histone Deacetylase Inhibitor, in Patients with Advanced Solid Tumors
Clinical Cancer Research
◽
10.1158/1078-0432.ccr-13-0735
◽
2013
◽
Vol 19
(19)
◽
pp. 5494-5504
◽
Cited By ~ 34
Author(s):
André T. Brunetto
◽
Joo Ern Ang
◽
Rohit Lal
◽
David Olmos
◽
L. Rhoda Molife
◽
...
Keyword(s):
Phase I
◽
Solid Tumors
◽
Histone Deacetylase
◽
Histone Deacetylase Inhibitor
◽
Phase I Study
◽
Advanced Solid Tumors
◽
Deacetylase Inhibitor
◽
Human Pharmacokinetic
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586 Phase I study of pan-histone deacetylase inhibitor abexinostat in combination with cisplatin in patients with advanced solid tumors
European Journal of Cancer
◽
10.1016/s0959-8049(14)70712-9
◽
2014
◽
Vol 50
◽
pp. 189
Author(s):
M. Campone
◽
N. Isambert
◽
R. Sabatier
◽
H. Castanie
◽
S. Zanetta
◽
...
Keyword(s):
Phase I
◽
Solid Tumors
◽
Histone Deacetylase
◽
Histone Deacetylase Inhibitor
◽
Phase I Study
◽
Advanced Solid Tumors
◽
Deacetylase Inhibitor
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Faculty of 1000 evaluation for A phase I study of histone deacetylase inhibitor, pracinostat (SB939), in pediatric patients with refractory solid tumors: IND203 a trial of the NCIC IND program/C17 pediatric phase I consortium.
F1000 - Post-publication peer review of the biomedical literature
◽
10.3410/f.718050520.793482822
◽
2013
◽
Author(s):
Burton Eisenberg
Keyword(s):
Phase I
◽
Solid Tumors
◽
Histone Deacetylase
◽
Histone Deacetylase Inhibitor
◽
Phase I Study
◽
Pediatric Patients
◽
Deacetylase Inhibitor
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Abstract 1172: Phase I study of histone deacetylase inhibitor belinostat in combination with warfarin in patients with solid tumors or hematological malignancies.
10.1158/1538-7445.am2013-1172
◽
2013
◽
Cited By ~ 2
Author(s):
Neeraj Agarwal
◽
Mark L. Wade
◽
Julia Batten
◽
Cynthia Davidson
◽
Show-Li Sun
◽
...
Keyword(s):
Phase I
◽
Solid Tumors
◽
Histone Deacetylase
◽
Histone Deacetylase Inhibitor
◽
Phase I Study
◽
Hematological Malignancies
◽
Deacetylase Inhibitor
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Faculty of 1000 evaluation for A phase I study of histone deacetylase inhibitor, pracinostat (SB939), in pediatric patients with refractory solid tumors: IND203 a trial of the NCIC IND program/C17 pediatric phase I consortium.
F1000 - Post-publication peer review of the biomedical literature
◽
10.3410/f.718050520.793482405
◽
2013
◽
Author(s):
Daniel Indelicato
Keyword(s):
Phase I
◽
Solid Tumors
◽
Histone Deacetylase
◽
Histone Deacetylase Inhibitor
◽
Phase I Study
◽
Pediatric Patients
◽
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A phase I pharmacokinetic (PK) and pharmacodynamic (PD) study of CHR-3996, a class 1 selective histone deacetylase inhibitor (HDACi), in patients with advanced solid tumors.
Journal of Clinical Oncology
◽
10.1200/jco.2010.28.15_suppl.2552
◽
2010
◽
Vol 28
(15_suppl)
◽
pp. 2552-2552
◽
Cited By ~ 3
Author(s):
U. Banerji
◽
L. van Doorn
◽
D. Papadatos-Pastos
◽
P. Debnam
◽
M. Tall
◽
...
Keyword(s):
Phase I
◽
Solid Tumors
◽
Histone Deacetylase
◽
Histone Deacetylase Inhibitor
◽
Advanced Solid Tumors
◽
Deacetylase Inhibitor
◽
Class 1
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Abstract A185: Phase I clinical, pharmacokinetic, and pharmacodynamic study of SB939, an oral histone deacetylase inhibitor (HDACi), in patients with advanced solid tumors
10.1158/1535-7163.targ-09-a185
◽
2009
◽
Author(s):
Lillian L. Siu
◽
Sebastien J. Hotte
◽
Eric X. Chen
◽
Hal W. Hirte
◽
Jean Powers
◽
...
Keyword(s):
Phase I
◽
Solid Tumors
◽
Histone Deacetylase
◽
Clinical Pharmacokinetic
◽
Histone Deacetylase Inhibitor
◽
Advanced Solid Tumors
◽
Deacetylase Inhibitor
◽
Pharmacodynamic Study
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A phase I study of histone deacetylase inhibitor, pracinostat (SB939), in pediatric patients with refractory solid tumors: IND203 a trial of the NCIC IND program/C17 pediatric phase I consortium
Pediatric Blood & Cancer
◽
10.1002/pbc.24694
◽
2013
◽
Vol 60
(11)
◽
pp. 1868-1874
◽
Cited By ~ 22
Author(s):
Alexandra P. Zorzi
◽
Mark Bernstein
◽
Yvan Samson
◽
Donna A. Wall
◽
Sunil Desai
◽
...
Keyword(s):
Phase I
◽
Solid Tumors
◽
Histone Deacetylase
◽
Histone Deacetylase Inhibitor
◽
Phase I Study
◽
Pediatric Patients
◽
Deacetylase Inhibitor
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Phase I Pharmacokinetic and Pharmacodynamic Study of LAQ824, a Hydroxamate Histone Deacetylase Inhibitor with a Heat Shock Protein-90 Inhibitory Profile, in Patients with Advanced Solid Tumors
Clinical Cancer Research
◽
10.1158/1078-0432.ccr-08-0376
◽
2008
◽
Vol 14
(20)
◽
pp. 6663-6673
◽
Cited By ~ 83
Author(s):
Johann S. de Bono
◽
Rebecca Kristeleit
◽
Anthony Tolcher
◽
Peter Fong
◽
Simon Pacey
◽
...
Keyword(s):
Heat Shock
◽
Heat Shock Protein
◽
Phase I
◽
Solid Tumors
◽
Histone Deacetylase
◽
Histone Deacetylase Inhibitor
◽
Heat Shock Protein 90
◽
Advanced Solid Tumors
◽
Deacetylase Inhibitor
◽
Pharmacodynamic Study
Download Full-text
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