Physiologically based pharmacokinetic modeling and simulation to predict drug–drug interactions of ivosidenib with CYP3A perpetrators in patients with acute myeloid leukemia

Chandra Prakash; Bin Fan; Alice Ke; Kha Le; Hua Yang

doi:10.1007/s00280-020-04148-3

Physiologically based pharmacokinetic modeling and simulation to predict drug–drug interactions of ivosidenib with CYP3A perpetrators in patients with acute myeloid leukemia

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-020-04148-3 ◽

2020 ◽

Vol 86 (5) ◽

pp. 619-632

Author(s):

Chandra Prakash ◽

Bin Fan ◽

Alice Ke ◽

Kha Le ◽

Hua Yang

Keyword(s):

Acute Myeloid Leukemia ◽

Drug Interactions ◽

Modeling And Simulation ◽

Myeloid Leukemia ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Acute Myeloid ◽

Pharmacokinetic Modeling And Simulation

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Physiologically-Based Pharmacokinetic Modeling and Simulation to Assess Potential Cytochrome P450 3A4 and Transporter-Mediated Drug−drug Interactions with Prucalopride as Victim

10.26226/morressier.57d6b2b9d462b8028d88ea6f ◽

2016 ◽

Author(s):

Aiqun Li

Keyword(s):

Cytochrome P450 ◽

Drug Interactions ◽

Modeling And Simulation ◽

Pharmacokinetic Modeling ◽

Cytochrome P450 3A4 ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pharmacokinetic Modeling And Simulation

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Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach

ACS Nano ◽

10.1021/acsnano.9b08142 ◽

2020 ◽

Vol 14 (3) ◽

pp. 3075-3095 ◽

Cited By ~ 16

Author(s):

Yi-Hsien Cheng ◽

Chunla He ◽

Jim E. Riviere ◽

Nancy A. Monteiro-Riviere ◽

Zhoumeng Lin

Keyword(s):

Modeling And Simulation ◽

Meta Analysis ◽

Pharmacokinetic Modeling ◽

Simulation Approach ◽

Physiologically Based Pharmacokinetic Modeling ◽

Nanoparticle Delivery ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pharmacokinetic Modeling And Simulation

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Evaluation of Exposure Change of Nonrenally Eliminated Drugs in Patients With Chronic Kidney Disease Using Physiologically Based Pharmacokinetic Modeling and Simulation

The Journal of Clinical Pharmacology ◽

10.1177/0091270011415528 ◽

2012 ◽

Vol 52 (S1) ◽

Cited By ~ 69

Author(s):

Ping Zhao ◽

Manuela de L. T. Vieira ◽

Joseph A. Grillo ◽

Pengfei Song ◽

Ta‐Chen Wu ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Modeling And Simulation ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pharmacokinetic Modeling And Simulation

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Physiologically Based Pharmacokinetic Modeling and Simulation in Pediatric Drug Development

CPT Pharmacometrics & Systems Pharmacology ◽

10.1038/psp.2014.45 ◽

2014 ◽

Vol 3 (11) ◽

pp. 1-13 ◽

Cited By ~ 77

Author(s):

A R Maharaj ◽

A N Edginton

Keyword(s):

Drug Development ◽

Modeling And Simulation ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Pediatric Drug ◽

Pediatric Drug Development ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pharmacokinetic Modeling And Simulation

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Best Practice in the Use of Physiologically Based Pharmacokinetic Modeling and Simulation to Address Clinical Pharmacology Regulatory Questions

Clinical Pharmacology & Therapeutics ◽

10.1038/clpt.2012.68 ◽

2012 ◽

Vol 92 (1) ◽

pp. 17-20 ◽

Cited By ~ 127

Author(s):

P Zhao ◽

M Rowland ◽

S-M Huang

Keyword(s):

Clinical Pharmacology ◽

Modeling And Simulation ◽

Best Practice ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pharmacokinetic Modeling And Simulation

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Assessing drug interaction risk of the grapefruit juice component and dietary supplement 6′,7′‐dihydroxybergamottin via physiologically‐based pharmacokinetic modeling and simulation

The FASEB Journal ◽

10.1096/fasebj.27.1_supplement.1103.4 ◽

2013 ◽

Vol 27 (S1) ◽

Author(s):

Garrett Robert Ainslie ◽

Brandon T Gufford ◽

Christina S Won ◽

Kristina K Wolf ◽

Mary F Paine

Keyword(s):

Drug Interaction ◽

Modeling And Simulation ◽

Dietary Supplement ◽

Grapefruit Juice ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pharmacokinetic Modeling And Simulation

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Physiologically Based Pharmacokinetic Modeling and Simulation of Sunitinib in Pediatrics

The AAPS Journal ◽

10.1208/s12248-020-0423-x ◽

2020 ◽

Vol 22 (2) ◽

Author(s):

Yanke Yu ◽

Steven G. DuBois ◽

Cynthia Wetmore ◽

Reza Khosravan

Keyword(s):

Modeling And Simulation ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pharmacokinetic Modeling And Simulation

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Predicting Nonlinear Pharmacokinetics of Omeprazole Enantiomers and Racemic Drug Using Physiologically Based Pharmacokinetic Modeling and Simulation: Application to Predict Drug/Genetic Interactions

Pharmaceutical Research ◽

10.1007/s11095-013-1293-z ◽

2014 ◽

Vol 31 (8) ◽

pp. 1919-1929 ◽

Cited By ~ 15

Author(s):

Fang Wu ◽

Lu Gaohua ◽

Ping Zhao ◽

Masoud Jamei ◽

Shiew-Mei Huang ◽

...

Keyword(s):

Modeling And Simulation ◽

Pharmacokinetic Modeling ◽

Genetic Interactions ◽

Nonlinear Pharmacokinetics ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pharmacokinetic Modeling And Simulation

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Investigating the Impact of Drug Crystallinity in Amorphous Tacrolimus Capsules on Pharmacokinetics and Bioequivalence Using Discriminatory In Vitro Dissolution Testing and Physiologically Based Pharmacokinetic Modeling and Simulation

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2017.12.024 ◽

2018 ◽

Vol 107 (5) ◽

pp. 1330-1341 ◽

Cited By ~ 22

Author(s):

Hitesh S. Purohit ◽

Niraj S. Trasi ◽

Dajun D. Sun ◽

Edwin C.Y. Chow ◽

Hong Wen ◽

...

Keyword(s):

Modeling And Simulation ◽

Pharmacokinetic Modeling ◽

In Vitro Dissolution ◽

Dissolution Testing ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

The Impact ◽

Pharmacokinetic Modeling And Simulation

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Dose Adjustment of Quetiapine and Aripiprazole for Pregnant Women Using Physiologically Based Pharmacokinetic Modeling and Simulation

Clinical Pharmacokinetics ◽

10.1007/s40262-020-00962-3 ◽

2020 ◽

Author(s):

Liang Zheng ◽

Shiwei Tang ◽

Rui Tang ◽

Miao Xu ◽

Xuehua Jiang ◽

...

Keyword(s):

Modeling And Simulation ◽

Pregnant Women ◽

Dose Adjustment ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pharmacokinetic Modeling And Simulation

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