A facile synthesis of polyaniline/polyethylene glycol/polyaniline terpolymers: preparation of electrospun conducting nanofibers by blending of the terpolymers with polycaprolactone

2013 ◽  
Vol 70 (12) ◽  
pp. 3529-3545 ◽  
Author(s):  
Leyla Shadi ◽  
Mohammad Karimi ◽  
Ali Akbar Entezami ◽  
Kazem Dindar Safa
2016 ◽  
Vol 7 (40) ◽  
pp. 6154-6158 ◽  
Author(s):  
Da Huang ◽  
Fei Yang ◽  
Xing Wang ◽  
Hong Shen ◽  
Yezi You ◽  
...  

Well-defined POSS hybrid polyacetal dendrimers functionalized with terminal polyethylene glycol and zwitterion could assemble into pH-responsive degradable micelles and nanofibers.


2018 ◽  
Vol 13 (6) ◽  
pp. 06D407 ◽  
Author(s):  
Sean Harvey ◽  
David Yuen Wah Ng ◽  
Jolanta Szelwicka ◽  
Lisa Hueske ◽  
Lothar Veith ◽  
...  

2009 ◽  
Vol 50 (1) ◽  
pp. 43-47 ◽  
Author(s):  
Feifei Tao ◽  
Cuiling Gao ◽  
Zheng Xu ◽  
Ziling Xue

Author(s):  
Zhendong Liu ◽  
Chunling Hu ◽  
Sainan Liu ◽  
Lihan Cai ◽  
Ying Zhou ◽  
...  

Fe(II)-baicalein-polyethylene glycol (Fe-BaP) nanoparticles were synthesized by a room temperature wet chemical method via coordination between Fe(II) and baicalein. Fe-BaP possessed high photothermal conversion efficiency (η=45.6%) and excellent antitumor efficacy...


2020 ◽  
Vol 6 (4) ◽  
pp. eaay8514 ◽  
Author(s):  
Anjali Sharma ◽  
Rishi Sharma ◽  
Zhi Zhang ◽  
Kevin Liaw ◽  
Siva P. Kambhampati ◽  
...  

Poor transport of neuropharmaceutics through central nervous system (CNS) barriers limits the development of effective treatments for CNS disorders. We present the facile synthesis of a novel neuroinflammation-targeting polyethylene glycol–based dendrimer (PEGOL-60) using an efficient click chemistry approach. PEGOL-60 reduces synthetic burden by achieving high hydroxyl surface density at low generation, which plays a key role in brain penetration and glia targeting of dendrimers in CNS disorders. Systemically administered PEGOL-60 crosses impaired CNS barriers and specifically targets activated microglia/macrophages at the injured site in diverse animal models for cerebral palsy, glioblastoma, and age-related macular degeneration, demonstrating its potential to overcome impaired blood-brain, blood-tumor-brain, and blood-retinal barriers and target key cells in the CNS. PEGOL-60 also exhibits powerful intrinsic anti-oxidant and anti-inflammatory effects in inflamed microglia in vitro. Therefore, PEGOL-60 is an effective vehicle to specifically deliver therapies to sites of CNS injury for enhanced therapeutic outcomes in a range of neuroinflammatory diseases.


2017 ◽  
Vol 8 (14) ◽  
pp. 2152-2163 ◽  
Author(s):  
Na Liu ◽  
Cui-Hong Ma ◽  
Rui-Wen Sun ◽  
Jian Huang ◽  
Chonglong Li ◽  
...  

A new Pd(ii) initiator bearing an alkyne headgroup was designed and synthesized.


Author(s):  
Kuixiong Gao ◽  
Randal E. Morris ◽  
Bruce F. Giffin ◽  
Robert R. Cardell

Several enzymes are involved in the regulation of anabolic and catabolic pathways of carbohydrate metabolism in liver parenchymal cells. The lobular distribution of glycogen synthase (GS), phosphoenolpyruvate carboxykinase (PEPCK) and glycogen phosphorylase (GP) was studied by immunocytochemistry using cryosections of normal fed and fasted rat liver. Since sections of tissue embedded in polyethylene glycol (PEG) show good morphological preservation and increased detectability for immunocytochemical localization of antigenic sites, and semithin sections of Visio-Bond (VB) embedded tissue provide higher resolution of cellular structure, we applied these techniques and immunogold-silver stain (IGSS) for a more accurate localization of hepatic carbohydrate metabolic enzymes.


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