Evaluation of prolidase activity and oxidative status in patients with knee osteoarthritis: relationships with radiographic severity and clinical parameters

2015 ◽  
Vol 35 (10) ◽  
pp. 1725-1731 ◽  
Author(s):  
Mehmet Akif Altay ◽  
Cemil Ertürk ◽  
Ali Bilge ◽  
Metin Yaptı ◽  
Ali Levent ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Oxidative Status ◽  
Clinical Parameters ◽  
Radiographic Severity ◽  
Prolidase Activity

The body composition of patients with knee osteoarthritis: relationship with clinical parameters and radiographic severity

2015 ◽  
Vol 27 (5) ◽  
pp. 673-679 ◽  
Author(s):  
Cemil Ertürk ◽  
Mehmet Akif Altay ◽  
Cemil Sert ◽  
Ali Levent ◽  
Metin Yaptı ◽  
...  
Keyword(s):  
Body Composition ◽  
Knee Osteoarthritis ◽  
The Body ◽  
Clinical Parameters ◽  
Radiographic Severity

Soluble P selectin in synovial fluid level is correlated with the radiographic severity of knee osteoarthritis

2010 ◽  
Vol 411 (19-20) ◽  
pp. 1529-1531 ◽  
Author(s):  
Tao Cheng ◽  
Feng-Feng Li ◽  
Song Zhao ◽  
Xiao-Chun Peng ◽  
Xian-Long Zhang
Keyword(s):  
Synovial Fluid ◽  
Knee Osteoarthritis ◽  
Fluid Level ◽  
Synovial Fluid Level ◽  
Radiographic Severity ◽  
Soluble P

Convolutional Neural Network-Based Automatic Measurement of Joint Space Width to Predict Radiographic Severity and Progression of Knee Osteoarthritis

2021 ◽  
Author(s):  
James Chung Wai Cheung ◽  
Yiu Chow TAM ◽  
Lok Chun CHAN ◽  
Ping Keung CHAN ◽  
Chunyi WEN
Keyword(s):  
Neural Network ◽  
Knee Osteoarthritis ◽  
Convolutional Neural Network ◽  
Pearson Correlation ◽  
Joint Space Width ◽  
Joint Space ◽  
Receiver Operating Curve ◽  
Radiographic Severity ◽  
X Ray ◽  
Space Width

Abstract Objectives To develop a deep convolutional neural network (CNN) for the segmentation of femur and tibia on plain x-ray radiographs, hence enabling an automated measurement of joint space width (JSW) to predict the severity and progression of knee osteoarthritis (KOA). Methods A CNN with ResU-Net architecture was developed for knee X-ray imaging segmentation. The efficiency was evaluated by the Intersection over Union (IoU) score by comparing the outputs with the annotated contour of the distal femur and proximal tibia. By leveraging imaging segmentation, the minimal and multiple JSWs in the tibiofemoral joint were estimated and then validated by radiologists’ measurements in the Osteoarthritis Initiative (OAI) dataset using Pearson correlation and Bland–Altman plot. The estimated JSWs were deployed to predict the radiographic severity and progression of KOA defined by Kellgren-Lawrence (KL) grades using the XGBoost model. The classification performance was assessed using F1 and area under receiver operating curve (AUC). Results The network has attained a segmentation efficiency of 98.9% IoU. Meanwhile, the agreement between the CNN-based estimation and radiologist’s measurement of minimal JSW reached 0.7801 (p < 0.0001). Moreover, the 32-point multiple JSW obtained the highest AUC score of 0.656 to classify KL-grade of KOA. Whereas the 64-point multiple JSWs achieved the best performance in predicting KOA progression defined by KL grade change within 48 months, with AUC of 0.621. The multiple JSWs outperform the commonly used minimum JSW with 0.587 AUC in KL-grade classification and 0.554 AUC in disease progression prediction. Conclusion Fine-grained characterization of joint space width of KOA yields comparable performance to the radiologist in assessing disease severity and progression. We provide a fully automated and efficient radiographic assessment tool for KOA.

Involvement of BDNF in knee osteoarthritis: the relationship with inflammation and clinical parameters

2014 ◽  
Vol 34 (8) ◽  
pp. 1153-1157 ◽  
Author(s):  
Adriano Prado Simão ◽  
Vanessa Amaral Mendonça ◽  
Tássio Málber de Oliveira Almeida ◽  
Sérgio Antunes Santos ◽  
Wellington Fabiano Gomes ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Clinical Parameters ◽  
The Relationship

scholarly journals Gender Differences in the Correlation between Symptom and Radiographic Severity in Patients with Knee Osteoarthritis

2010 ◽  
Vol 468 (7) ◽  
pp. 1749-1758 ◽  
Author(s):  
Hyung Joon Cho ◽  
Chong Bum Chang ◽  
Jae Ho Yoo ◽  
Sung Ju Kim ◽  
Tae Kyun Kim
Keyword(s):  
Gender Differences ◽  
Knee Osteoarthritis ◽  
Radiographic Severity

scholarly journals Does the radiographic severity of knee osteoarthritis correlates with the duration of symptoms, pain intensity and medication use?

2018 ◽  
Vol 26 ◽  
pp. S255-S256 ◽  
Author(s):  
L. De Polo ◽  
M. Choinière ◽  
N.J. Bureau ◽  
M. Durand ◽  
A. Cagnin ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Pain Intensity ◽  
Medication Use ◽  
Duration Of Symptoms ◽  
Radiographic Severity

Serum prolidase activity and oxidative status in Helicobacter pylori infection

2007 ◽  
Vol 40 (1-2) ◽  
pp. 37-40 ◽  
Author(s):  
Mehmet Aslan ◽  
Yasar Nazligul ◽  
Mehmet Horoz ◽  
Cengiz Bolukbas ◽  
Fusun F. Bolukbas ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Oxidative Status ◽  
Helicobacter Pylori Infection ◽  
Prolidase Activity

Association of plasma and synovial fluid interferon-γ inducible protein-10 with radiographic severity in knee osteoarthritis

2011 ◽  
Vol 44 (14-15) ◽  
pp. 1218-1222 ◽  
Author(s):  
Natthaphon Saetan ◽  
Sittisak Honsawek ◽  
Aree Tanavalee ◽  
Saran Tantavisut ◽  
Pongsak Yuktanandana ◽  
...  
Keyword(s):  
Synovial Fluid ◽  
Knee Osteoarthritis ◽  
Interferon Γ ◽  
Radiographic Severity ◽  
Inducible Protein
Sign in / Sign up

Export Citation Format

Share Document