Risk stratification of ductal carcinoma in situ using whole-lesion histogram analysis of the apparent diffusion coefficient

2018 ◽  
Vol 29 (2) ◽  
pp. 485-493 ◽  
Author(s):  
Jin You Kim ◽  
Jin Joo Kim ◽  
Ji Won Lee ◽  
Nam Kyung Lee ◽  
Geewon Lee ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Risk Stratification ◽  
Apparent Diffusion Coefficient ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Histogram Analysis ◽  
Apparent Diffusion

Low diffusion level within a fibroadenoma as the sole sign of ductal carcinoma in situ: A case report

2021 ◽  
pp. 1-4
Author(s):  
Corrado Tagliati ◽  
Giuseppe Lanni ◽  
Federico Cerimele ◽  
Antonietta Di Martino ◽  
Valentina Calamita ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Surgical Excision ◽  
Small Region ◽  
Apparent Diffusion Coefficient Value ◽  
Apparent Diffusion

We present a case of ductal carcinoma in situ within a fibroadenoma. Breast cancer arising within fibroadenoma incidence ranges from 0.125% to 0.02%, and ductal carcinoma in situ is not the most frequent malignancy that can be found within a fibroadenoma. Dynamic contrast-enhanced magnetic resonance imaging showed an oval mass with circumscribed margins and dark internal septations, suspicious for fibroadenoma. According to European Society of Breast Radiology diffusion-weighted imaging consensus, mean apparent diffusion coefficient value obtained by drawing a small region of interest on the lesion apparent diffusion coefficient map showed a low diffusion level. Therefore, ductal carcinoma in situ within a fibroadenoma was diagnosed at final pathology after surgical excision.

scholarly journals Apparent Diffusion Coefficient as an MR Imaging Biomarker of Low-Risk Ductal Carcinoma in Situ: A Pilot Study

Radiology ◽  
2011 ◽  
Vol 260 (2) ◽  
pp. 364-372 ◽  
Author(s):  
Mami Iima ◽  
Denis Le Bihan ◽  
Ryosuke Okumura ◽  
Tomohisa Okada ◽  
Koji Fujimoto ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Pilot Study ◽  
Mr Imaging ◽  
Apparent Diffusion Coefficient ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Imaging Biomarker ◽  
Apparent Diffusion

Evaluation of Apparent Diffusion Coefficient to Predict Grade, Microinvasion, and Invasion in Ductal Carcinoma In Situ of the Breast

2015 ◽  
Vol 22 (12) ◽  
pp. 1483-1488 ◽  
Author(s):  
Heba Hussein ◽  
Caroline Chung ◽  
Hadas Moshonov ◽  
Naomi Miller ◽  
Supriya R. Kulkarni ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Apparent Diffusion

Detection of invasive components in cases of breast ductal carcinoma in situ on biopsy by using apparent diffusion coefficient MR parameters

2013 ◽  
Vol 23 (10) ◽  
pp. 2705-2712 ◽  
Author(s):  
Naoko Mori ◽  
Hideki Ota ◽  
Shunji Mugikura ◽  
Chiaki Takasawa ◽  
Junya Tominaga ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Apparent Diffusion

Histogram analysis of volume-based apparent diffusion coefficient in breast cancer

2017 ◽  
Vol 58 (11) ◽  
pp. 1294-1302 ◽  
Author(s):  
Ga Eun Park ◽  
Sung Hun Kim ◽  
Eun Jeong Kim ◽  
Bong Joo Kang ◽  
Mi Sun Park
Keyword(s):  
Breast Cancer ◽  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Ductal Carcinoma ◽  
Histogram Analysis ◽  
Invasive Ductal Cancer ◽  
Diffusion Weighted Images ◽  
Apparent Diffusion ◽  
Adc Values ◽  
Magnetic Resonance Imaging Mri

Background Breast cancer is a heterogeneous disease. Recent studies showed that apparent diffusion coefficient (ADC) values have various association with tumor aggressiveness and prognosis. Purpose To evaluate the value of histogram analysis of ADC values obtained from the whole tumor volume in invasive ductal cancer (IDC) and ductal carcinoma in situ (DCIS). Material and Methods This retrospective study included 201 patients with confirmed DCIS (n = 37) and IDC (n = 164). The IDC group was divided into two groups based on the presence of a DCIS component: IDC–DCIS (n = 76) and pure IDC (n = 88). All patients underwent preoperative breast magnetic resonance imaging (MRI) with diffusion-weighted images at 3.0 T. Histogram parameters of cumulative ADC values, skewness, and kurtosis were calculated and statistically analyzed. Results The differences between DCIS, IDC–DCIS, and pure IDC were significant in all percentiles of ADC values, in descending order of DCIS, IDC–DCIS, and pure IDC. IDC showed significantly lower ADC values than DCIS, and ADC50 was the best indicator for discriminating IDC from DCIS, with a threshold of 1.185 × 10–3 mm2/s (sensitivity of 82.9%, specificity of 75.7%). However, multivariate analysis of obtained ADC values showed no significant differences between DCIS, IDC–DCIS, and pure IDC ( P > 0.05). Conclusion Volume-based ADC values showed association with heterogeneity of breast cancer. However, there was no additional diagnostic performance in histogram analysis for differentiating between DCIS, IDC–DCIS, and pure IDC.

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