Proton magnetic resonance spectroscopy of the brain of a neonate with nonketotic hyperglycinemia: in vivo–in vitro (ex vivo) correlation

2001 ◽  
Vol 12 (4) ◽  
pp. 858-861 ◽  
Author(s):  
T. Huisman ◽  
T. Thiel ◽  
B. Steinmann ◽  
G. Zeilinger ◽  
E. Martin
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Proton Magnetic Resonance ◽  
Proton Magnetic Resonance Spectroscopy ◽  
Ex Vivo ◽  
Resonance Spectroscopy ◽  
Nonketotic Hyperglycinemia ◽  
The Brain

In vivo proton magnetic resonance spectroscopy of intraventricular tumours of the brain

2009 ◽  
Vol 19 (8) ◽  
pp. 2049-2059 ◽  
Author(s):  
Carles Majós ◽  
Carles Aguilera ◽  
Mònica Cos ◽  
Àngels Camins ◽  
Ana P. Candiota ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Proton Magnetic Resonance ◽  
Proton Magnetic Resonance Spectroscopy ◽  
Resonance Spectroscopy ◽  
Intraventricular Tumours ◽  
The Brain

Brain Macromolecules: In Vivo Measurement by Proton Magnetic Resonance Spectroscopy

1996 ◽  
Vol 2 (6) ◽  
pp. 309-312 ◽  
Author(s):  
Glenn D. Graham
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Proton Magnetic Resonance ◽  
Proton Magnetic Resonance Spectroscopy ◽  
Cell Activity ◽  
Resonance Spectroscopy ◽  
Brain Lipids ◽  
Subacute Stroke

New single- and multiple-volume in vivo proton magnetic resonance spectroscopy techniques detect signals from brain macromolecules and can separate them from overlapping small molecule resonances. In vitro and animal studies have identified these resonances as arising from cytosolic proteins and mobile lipids. Increased macromolecule signals from lipids have been detected in both subacute stroke and in active multiple sclerosis plaques that reflect tissue breakdown and, in conjunction with elevated lactate, can be used to monitor phagocytic cell activity. The ability to follow changes in brain lipids and proteins should help to elucidate biochemical abnormalities accompanying a variety of pathological conditions.

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