Real-time cancer diagnosis during prostate biopsy: ex vivo evaluation of full-field optical coherence tomography (FFOCT) imaging on biopsy cores

2015 ◽  
Vol 34 (2) ◽  
pp. 237-243 ◽  
Author(s):  
Jonathan Lopater ◽  
Pierre Colin ◽  
Frédéric Beuvon ◽  
Mathilde Sibony ◽  
Eugénie Dalimier ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Real Time ◽  
Cancer Diagnosis ◽  
Prostate Biopsy ◽  
Ex Vivo ◽  
Optical Coherence ◽  
Full Field

scholarly journals Polarization-sensitive optical coherence tomography monitoring of percutaneous radiofrequency ablation in left atrium of living swine

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xiaowei Zhao ◽  
Ohad Ziv ◽  
Reza Mohammadpour ◽  
Benjamin Crosby ◽  
Walter J. Hoyt ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Radiofrequency Ablation ◽  
Left Atrium ◽  
Real Time ◽  
Wall Thickness ◽  
Ex Vivo ◽  
Optical Coherence ◽  
Percutaneous Radiofrequency Ablation ◽  
Cardiac Wall

AbstractRadiofrequency ablation (RFA) is commonly used to treat atrial fibrillation (AF). However, the outcome is often compromised due to the lack of direct real-time feedback to assess lesion transmurality. In this work, we evaluated the ability of polarization-sensitive optical coherence tomography (PSOCT) to measure cardiac wall thickness and assess RF lesion transmurality during left atrium (LA) RFA procedures. Quantitative transmural lesion criteria using PSOCT images were determined ex vivo using an integrated PSOCT-RFA catheter and fresh swine hearts. LA wall thickness of living swine was measured with PSOCT and validated with a micrometer after harvesting the heart. A total of 38 point lesions were created in the LA of 5 living swine with the integrated PSOCT-RFA catheter using standard clinical RFA procedures. For all lesions with analyzable PSOCT images, lesion transmurality was assessed with a sensitivity of 89% (17 of 19 tested positive) and a specificity of 100% (5 of 5 tested negative) using the quantitative transmural criteria. This is the first report of using PSOCT to assess LA RFA lesion transmurality in vivo. The results indicate that PSOCT may potentially provide direct real-time feedback for LA wall thickness and lesion transmurality.

Applying RGB LED in full-field optical coherence tomography for real-time full-color tissue imaging

2014 ◽  
Vol 53 (22) ◽  
pp. E56 ◽  
Author(s):  
Bor-Wen Yang ◽  
Yu-Yen Wang ◽  
Yu-Min Lin ◽  
Yu-Shan Juan ◽  
Hung-Te Chen ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Real Time ◽  
Tissue Imaging ◽  
Optical Coherence ◽  
Full Field ◽  
Full Color

Rapid evaluation of fresh ex vivo kidney tissue with full field optical coherence tomography

Pathology ◽  
2014 ◽  
Vol 46 ◽  
pp. S77-S78
Author(s):  
Manu Jain ◽  
Brian Dale Robinson ◽  
Maria M. Shevchuk ◽  
Bekheit Salamoon ◽  
Douglas S. Scherr ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Ex Vivo ◽  
Kidney Tissue ◽  
Rapid Evaluation ◽  
Optical Coherence ◽  
Full Field

Anterior segment imaging in vivo in rats and ex vivo in mice using full-field optical coherence tomography

2006 ◽  
Author(s):  
Kate Grieve ◽  
Petr Kuchynka ◽  
Manuel Simonutti ◽  
Arnaud Dubois ◽  
Jean-François Le Gargasson ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Ex Vivo ◽  
Anterior Segment ◽  
Optical Coherence ◽  
Full Field ◽  
Anterior Segment Imaging
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