Age-dependent differences in clinical phenotype and prognosis in heart failure with mid-range ejection compared with heart failure with reduced or preserved ejection fraction

2019 ◽  
Vol 108 (12) ◽  
pp. 1394-1405 ◽  
Author(s):  
Xiaojing Chen ◽  
Gianluigi Savarese ◽  
Ulf Dahlström ◽  
Lars H. Lund ◽  
Michael Fu
Author(s):  
Evandro Tinoco Mesquita ◽  
Antonio José Lagoeiro Jorge ◽  
Celso Vale Souza Junior ◽  
Thais Ribeiro de Andrade

2012 ◽  
Vol 110 (6) ◽  
pp. 870-876 ◽  
Author(s):  
Venkatesh Y. Anjan ◽  
Timothy M. Loftus ◽  
Michael A. Burke ◽  
Nausheen Akhter ◽  
Gregg C. Fonarow ◽  
...  

2008 ◽  
Vol 7 ◽  
pp. 62-63
Author(s):  
J NUNEZ ◽  
L MAINAR ◽  
G MINANA ◽  
R ROBLES ◽  
J SANCHIS ◽  
...  

2010 ◽  
Vol 6 (2) ◽  
pp. 33 ◽  
Author(s):  
Christopher R deFilippi ◽  
G Michael Felker ◽  
◽  

For many with heart failure, including the elderly and those with a preserved ejection fraction, both risk stratification and treatment are challenging. For these large populations and others there is increasing recognition of the role of cardiac fibrosis in the pathophysiology of heart failure. Galectin-3 is a novel biomarker of fibrosis and cardiac remodelling that represents an intriguing link between inflammation and fibrosis. In this article we review the biology of galectin-3, recent clinical research and its application in the management of heart failure patients.


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