scholarly journals A possible role for ghrelin, leptin, brain-derived neurotrophic factor and docosahexaenoic acid in reducing the quality of life of coeliac disease patients following a gluten-free diet

2015 ◽  
Vol 56 (2) ◽  
pp. 807-818 ◽  
Author(s):  
Francesco Russo ◽  
Guglielmina Chimienti ◽  
Caterina Clemente ◽  
Carla Ferreri ◽  
Antonella Orlando ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Docosahexaenoic Acid ◽  
Coeliac Disease ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Gluten Free Diet ◽  
Gluten Free

scholarly journals The impact of symptoms on quality of life before and after diagnosis of coeliac disease: the results from a Polish population survey and comparison with the results from the United Kingdom

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Emilia Majsiak ◽  
Magdalena Choina ◽  
Dominik Golicki ◽  
Alastair M. Gray ◽  
Bożena Cukrowska
Keyword(s):  
Quality Of Life ◽  
United Kingdom ◽  
Coeliac Disease ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
The United Kingdom ◽  
Before And After ◽  
The Mean ◽  
The Uk

Abstract Background Coeliac disease (CD) is characterised by diverse clinical symptoms, which may cause diagnostic problems and reduce the patients’ quality of life. A study conducted in the United Kingdom (UK) revealed that the mean time between the onset of coeliac symptoms and being diagnosed was above 13 years. This study aimed to analyse the diagnostic process of CD in Poland and evaluate the quality of life of patients before and after CD diagnosis. In addition, results were compared to the results of the original study conducted in the UK. Methods The study included 2500 members of the Polish Coeliac Society. The patients were asked to complete a questionnaire containing questions on socio-demographic factors, clinical aspects and quality of life, using the EQ-5D questionnaire. Questionnaires received from 796 respondents were included in the final analysis. Results The most common symptoms reported by respondents were bloating (75%), abdominal pain (72%), chronic fatigue (63%) and anaemia (58%). Anaemia was the most persistent symptom, with mean duration prior to CD diagnosis of 9.2 years, whereas diarrhoea was observed for the shortest period (4.7 years). The mean duration of any symptom before CD diagnosis was 7.3 years, compared to 13.2 years in the UK. CD diagnosis and the introduction of a gluten-free diet substantially improved the quality of life in each of the five EQ-5D-5L health dimensions: pain and discomfort, anxiety and depression, usual activities, self-care and mobility (p < 0.001), the EQ-Index by 0.149 (SD 0.23) and the EQ-VAS by 30.4 (SD 28.3) points. Conclusions Duration of symptoms prior to the diagnosis of CD in Poland, although shorter than in the UK, was long with an average of 7.3 years from first CD symptoms. Faster CD diagnosis after the onset of symptoms in Polish respondents may be related to a higher percentage of children in the Polish sample. Introduction of a gluten-free diet improves coeliac patients’ quality of life. These results suggest that doctors should be made more aware of CD and its symptoms across all age groups.

scholarly journals Effectiveness of nutritional supplementation for children with coeliac disease who are on a gluten-free diet

2019 ◽  
pp. 138-146
Author(s):  
V. A. Kur’yaninova ◽  
M. V. Stoyan ◽  
I. N. Zakharova ◽  
L. Ya. Klimov ◽  
V. S. Kashnikov ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Coeliac Disease ◽  
Physical Development ◽  
Nutritional Supplementation ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Nutrient Deficiencies ◽  
Quality Of Life Indicators ◽  
Enteric Nutrition

Patients on a gluten-free diet are at risk of developing polyhypoavitaminosis and deficiency states, which requires the supplementation of their diet to prevent nutrient deficiencies. The aim of the study: to analyze the dynamics of anthropometric and laboratory parameters, components of the quality of life in children with coeliac disease on the background of a month-long course of administration of hypercaloric mixture for enteric nutrition. Materials and methods: 45 children with coeliac disease aged 2-10 years (mean age 6.3 ± 0.3 years) on a strict gluten-free diet for more than one year. All patients received additional enteric nutrition with a hypercaloric mixture in the volume of 200 ml/day (300 kcal/day) for 1 month as a supplement to the main food ration. Two groups of patients receiving the supplement in 2012-2013 and 2017-2018 were identified. Physical development was assessed under the WHO AnthroPlus programme. The quality of life indicators were assessed using the PedQL 4.0 questionnaire. Results: the total frequency of protein-сalorie deficiency (PCD) before the course of nutritional supplementation was 13 (28.9%) cases, while acute PCD was diagnosed in 6 (13.3%) and chronic PCD in 7 (15.6%) patients. Against the background of the course of nutritious supplementation in children with coeliac disease, there was a significant reduction in weight, height and BMI in both groups. Patients in 2012-2013 initially had a greater gap in weight and height compared to children in 2017-2018. There was an improvement in the sum of the quality of life indicators by 6.3% for children in the first group and by 4.3% for children in the second group against the background of nutritional supplementation. Conclusions: Enrichment of children’s diets with a hypercaloric blend of dietary fiber helps to accelerate the pace of physical development, reduce the number of children with diabetes mellitus, improve hemogram rates and most components of quality of life.

scholarly journals Evaluation of the quality of life by means of WHOQOL-BREF questionnaire among people with coeliac disease, allergy and oversensitivity to gluten who follow the gluten-free diet

2014 ◽  
Vol 20 (3) ◽  
pp. 241-244
Author(s):  
Anna Brończyk-Puzoń ◽  
Joanna Bieniek ◽  
Aneta Koszowska ◽  
Justyna Nowak ◽  
Anna Dittfeld ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Coeliac Disease ◽  
Gluten Free Diet ◽  
Gluten Free

Effect of an oats‐containing gluten‐free diet on symptoms and quality of life in coeliac disease. A randomized study

2004 ◽  
Vol 39 (1) ◽  
pp. 27-31 ◽  
Author(s):  
M. Peräaho ◽  
K. Kaukinen ◽  
K. Mustalahti ◽  
N. Vuolteenaho ◽  
M. Mäki ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Coeliac Disease ◽  
Randomized Study ◽  
Gluten Free Diet ◽  
Gluten Free

scholarly journals Predictors of adherence to a gluten-free diet in coeliac disease: do knowledge, attitudes, beliefs, quality of life and symptoms play a role?

2020 ◽  
Vol 79 (OCE1) ◽  
Author(s):  
Eirini Dimidi ◽  
Bonita Amilah ◽  
Aikaterini Ageridou ◽  
Charlotte Foster ◽  
Jaspreet Singh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Coeliac Disease ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Predictors Of Adherence

Affective disorders and quality of life in adult coeliac disease patients on a gluten-free diet

2003 ◽  
Vol 15 (12) ◽  
pp. 1287-1292 ◽  
Author(s):  
Tiziana Fera ◽  
Barbara Cascio ◽  
Guiseppe Angelini ◽  
Silvia Martini ◽  
Carla Sategna Guidetti
Keyword(s):  
Quality Of Life ◽  
Coeliac Disease ◽  
Affective Disorders ◽  
Gluten Free Diet ◽  
Gluten Free

Coeliac disease and psychiatric comorbidity: epidemiology, pathophysiological mechanisms, quality-of-life, and gluten-free diet effects

2017 ◽  
Vol 29 (5) ◽  
pp. 489-503 ◽  
Author(s):  
Giulia Cossu ◽  
Mauro Giovanni Carta ◽  
Federico Contu ◽  
Quirico Mela ◽  
Luigi Demelia ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Coeliac Disease ◽  
Psychiatric Comorbidity ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Pathophysiological Mechanisms
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