Primary metastasized extraskeletal Ewing sarcoma of the vulva: report of a case and review of the literature

2011 ◽  
Vol 285 (3) ◽  
pp. 785-789 ◽  
Author(s):  
Katharina Kelling ◽  
Frank Noack ◽  
Christopher Altgassen ◽  
Peter Kujath ◽  
Michael K. Bohlmann ◽  
...  
2003 ◽  
Vol 48 (1) ◽  
pp. 85 ◽  
Author(s):  
Kijun Kim ◽  
Hyun Seouk Jung ◽  
Jae Hee Lee ◽  
Kyung Myung Sohn ◽  
Sung Yong Lee

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Hyma Polimera ◽  
Prashanth Moku ◽  
Shady Piedra Abusharar ◽  
Monali Vasekar ◽  
Jayakrishna Chintanaboina

Ewing sarcoma (ES) is a highly aggressive malignant bone cancer. ES is part of the Ewing sarcoma family of tumors (ESFT), which express characteristic t(11;22) translocation as well as higher levels of CD99. Given that metastasis and tumor burden are significant prognostic factors in patient’s response to treatment, prompt diagnosis is needed to effectively treat ESFT patients. However, the challenges in classifying and characterizing ESFT complicate effective management and treatment of ES. In this report, we present a rare case of ES metastasis to the pancreas. Upon review of the literature, we found 39 cases of ESFT involving the pancreas, but only 3 were metastatic to the pancreas while the remaining cases of ESFT primarily originated from the pancreas. Given the rarity of such metastasis, the positive outcome in our patient’s case may explain the importance of prompt diagnosis in order to initiate appropriate treatment.


2021 ◽  
Vol 80 ◽  
pp. 105676
Author(s):  
Tomohiko Sakuda ◽  
Taisuke Furuta ◽  
Muhammad Phetrus Johan ◽  
Koji Arihiro ◽  
Nobuo Adachi

2020 ◽  
pp. 311-316
Author(s):  
Simone Mocellin

2019 ◽  
Vol 18 (3) ◽  
pp. 177 ◽  
Author(s):  
Sonal Saran ◽  
Annu Kharbanda ◽  
Sunil Malik

2021 ◽  
pp. 55-56
Author(s):  
K Pratyusha ◽  
Satish Arakeri ◽  
Surekha Arakeri

Introduction: Extraskeletal Ewing sarcoma/PNET is a small round cell sarcoma showing gene fusions of EWSR1-FLI1. A 28-year-old male patient presented with right ank pain and low gr Case Report: ade fever since 15 days. On examination: a mass was palpable in the right hypochondrium. Provisional diagnosis of Liver abscess has been made. USG abdomen shows features cystic lesion in the liver with internal septation ?Liver abscess /Hydatid cyst. Intraoperatively, tumor was seen attached to upper pole of kidney. Since tumor was large, it was ruptured intraoperatively and debulking surgery has been done. Under microscopy, tumor was arranged in sheets with intervening stroma showing desmoplastic reaction. Perivascular pseudorosettes are seen. The diagnosis of malignant small round cell tumor has been given. On immunohistochemistry, tumor cells are positive for Vimentin, CD99, NKX2.2 , FLI1, Neurolaments, Synaptophysin with focal immunoreactivity for EMA, Pancytokeratin. Final diagnosis was EXTRASKELETAL EWING SARCOMA/PNET. Discussion: Extra-skeletal Ewing sarcoma/PNET is malignant soft tissue tumor seen in chest wall, thigh, paravertebal region etc. Retroperitoneum is a least common site. Most common presentation is swelling in the soft tissue with compressive symptoms. Histologically, it is composed of undifferentiated small round cells. Conclusion: Clinical examination and radiological ndings leads to ambiguous diagnosis in Ewing sarcoma/PNET. Hence proper histopathological study is essential for nal diagnosis.


2012 ◽  
Vol 5 (3) ◽  
pp. 153-159 ◽  
Author(s):  
Tariq S. Hakky ◽  
Americo A. Gonzalvo ◽  
Jorge L. Lockhart ◽  
Alejandro R. Rodriguez

2004 ◽  
Vol 78 (2) ◽  
pp. 715-717 ◽  
Author(s):  
Atilla Eroğlu ◽  
İbrahim Can Kürkçüoğlu ◽  
Nurettin Karaoğlanoğlu ◽  
Fatih Alper ◽  
Cemal Gündoğdu

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